Infertility, Female

Also known as: Female infertility / Infertility female / Infertility, female, of unspecified origin

DrugDrug NameDrug Description
DB00396ProgesteroneProgesterone is a hormone that occurs naturally in females, and is essential for endometrial receptivity, embryo implantation, and the successful establishment of pregnancy. A low progesterone concentration or an insufficient response to progesterone can cause infertility and pregnancy loss [A175609]. Progesterone is used in various contraceptive preparations to prevent ovulation and fertilization [T481], [A175612] as well as in other formulations to promote and support pregnancy. Please see [Medroxyprogesterone acetate], [Megestrol acetate], [Dydrogesterone] and [Hydroxyprogesterone] entries for information on various other forms of progesterone. Pharmaceutical progesterone is made from a plant source as a starting material and is chemically identical to progesterone of human ovarian origin [FDA label]. Progesterone is available in gelatinized capsule form, vaginal gel form, tablet form, vaginal insert form, and injection form, all used for various purposes [Label,F3898,F3904,F3901,F3907].
DrugDrug NameTargetType
DB00396ProgesteroneProgesterone receptortarget
DB00396ProgesteroneEstrogen receptor alphatarget
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00396ProgesteroneCytochrome P450 2C19enzyme
DB00396ProgesteroneCytochrome P450 2C9enzyme
DB00396ProgesteroneCytochrome P450 3A4enzyme
DB00396ProgesteroneCytochrome P450 3A5enzyme
DB00396ProgesteroneCytochrome P450 3A7enzyme
DB00396ProgesteroneMultidrug resistance protein 1transporter
DB00396ProgesteroneSolute carrier family 22 member 2transporter
DB00396ProgesteroneSolute carrier family 22 member 1transporter
DB00396ProgesteroneSolute carrier family 22 member 3transporter
DB00396ProgesteroneBile salt export pumptransporter
DB00396ProgesteroneMultidrug resistance-associated protein 1transporter
DB00396ProgesteroneSodium/bile acid cotransportertransporter
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB00396ProgesteroneCytochrome P450 1A1enzyme
DB00396ProgesteroneCytochrome P450 1B1enzyme
DB00396ProgesteroneCytochrome P450 2A6enzyme
DB00396ProgesteroneCytochrome P450 2D6enzyme
DB00396ProgesteroneMineralocorticoid receptortarget
DB00396ProgesteroneKappa-type opioid receptortarget
DB00396ProgesteroneAlpha-1-acid glycoprotein 1target
DB00396ProgesteroneGlucocorticoid receptortarget
DB00396ProgesteroneAndrogen receptortarget
DB00396ProgesteroneSex hormone-binding globulintarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
DB00396ProgesteroneATP-binding cassette sub-family G member 2transporter
DB00396ProgesteroneEstrogen receptor betatarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB00945Acetylsalicylic acid0Completed1
DB01132Pioglitazone0Completed1
DB00052Somatotropin0Recruiting1
DB00066Follitropin1Not Yet Recruiting1
DB01708Prasterone1Completed1
DB06825Triptorelin1Recruiting1
DB00099Filgrastim1 / 2Completed1
DB00099Filgrastim1 / 2Terminated1
DB00019Pegfilgrastim1 / 2Completed1
DB00019Pegfilgrastim1 / 2Terminated1
DB09153Sodium chloride1 / 2Completed1
DB09153Sodium chloride1 / 2Terminated1
DB00043Omalizumab2Recruiting1
DB00882Clomifene2 / 3Unknown Status1
DB06825Triptorelin2 / 3Recruiting1
DB06151Acetylcysteine3Completed1
DB00050Cetrorelix3Recruiting1
DB09066Corifollitropin alfa3Recruiting1
DB00304Desogestrel3Recruiting1
DB00378Dydrogesterone3Completed2
DB00965Ethiodized oil3Recruiting1
DB00158Folic Acid3Recruiting1
DB00066Follitropin3Completed1
DB09024Follitropin3Completed1
DB00066Follitropin3Recruiting2
DB13178Inositol3Recruiting1
DB01006Letrozole3Recruiting1
DB00007Leuprolide3Withdrawn1
DB00044Lutropin alfa3Recruiting1
DB01083Orlistat3Active Not Recruiting1
DB09153Sodium chloride3Withdrawn1
DB00864Tacrolimus3Recruiting1
DB06825Triptorelin3Recruiting1
DB00316Acetaminophen4Not Yet Recruiting1
DB00050Cetrorelix4Active Not Recruiting1
DB00882Clomifene4Completed1
DB00882Clomifene4Recruiting1
DB09066Corifollitropin alfa4Recruiting1
DB00378Dydrogesterone4Not Yet Recruiting1
DB00813Fentanyl4Not Yet Recruiting1
DB00066Follitropin4Not Yet Recruiting1
DB09024Follitropin4Not Yet Recruiting1
DB00066Follitropin4Recruiting3
DB09024Follitropin4Recruiting1
DB00044Lutropin alfa4Not Yet Recruiting1
DB00044Lutropin alfa4Recruiting3
DB00032Menotropins4Not Yet Recruiting1
DB00032Menotropins4Recruiting2
DB00134Methionine4Completed1
DB00396Progesterone4Not Yet Recruiting1
DB00818Propofol4Not Yet Recruiting1
DB09153Sodium chloride4Recruiting1
DB09422Soybean oil4Completed1
DB00624Testosterone4Recruiting1
DB06825Triptorelin4Not Yet Recruiting1
DB06825Triptorelin4Recruiting1
DB06825Triptorelin4Unknown Status1
DB00094Urofollitropin4Recruiting1
DB09059AtosibanNot AvailableRecruiting1
DB00050CetrorelixNot AvailableRecruiting1
DB09126Chorionic Gonadotropin (Human)Not AvailableNot Yet Recruiting2
DB09126Chorionic Gonadotropin (Human)Not AvailableRecruiting1
DB01190ClindamycinNot AvailableRecruiting1
DB09066Corifollitropin alfaNot AvailableCompleted1
DB01234DexamethasoneNot AvailableNot Yet Recruiting1
DB00066FollitropinNot AvailableTerminated1
DB06785GanirelixNot AvailableRecruiting1
DB00281LidocaineNot AvailableRecruiting1
DB06655LiraglutideNot AvailableRecruiting1
DB00032MenotropinsNot AvailableEnrolling by Invitation1
DB00032MenotropinsNot AvailableRecruiting2
DB06825TriptorelinNot AvailableEnrolling by Invitation1
DB06825TriptorelinNot AvailableRecruiting1
DB08867UlipristalNot AvailableCompleted1