Fibromyalgia

Also known as: Fibromyalgias / Fibromyositis / Fibrositis / Muscular rheumatism / Fibromyalgia syndrome

DrugDrug NameDrug Description
DB00476DuloxetineA serotonin norepinephrine reuptake inhibitor used to treat generalized anxiety disorder, neuropathic pain, osteoarthritis, and stress incontinence.
DB04896MilnacipranA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of fibromyalgia and a short-term treatment of major depressive disorder.
DB00370MirtazapineA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
DB00230PregabalinAn anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.
DB00656TrazodoneA serotonin uptake inhibitor used to treat major depressive disorder.
DrugDrug NameTargetType
DB00476DuloxetineSodium-dependent serotonin transportertarget
DB00476DuloxetineSodium-dependent dopamine transportertarget
DB00476DuloxetineSodium-dependent noradrenaline transportertarget
DB00476DuloxetineCytochrome P450 1A2enzyme
DB00476DuloxetineCytochrome P450 2D6enzyme
DB00476DuloxetineCytochrome P450 2C9enzyme
DB00476DuloxetineSerum albumincarrier
DB00476Duloxetinealpha1-acid glycoproteincarrier
DB00476DuloxetineP-glycoprotein 1transporter
DB04896MilnacipranSodium-dependent serotonin transportertarget
DB04896MilnacipranSodium-dependent noradrenaline transportertarget
DB04896MilnacipranNMDA receptortarget
DB04896MilnacipranCytochrome P450 3A4enzyme
DB00370Mirtazapine5-hydroxytryptamine receptor 2Atarget
DB00370Mirtazapine5HT3 serotonin receptortarget
DB00370MirtazapineAlpha-2A adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Ctarget
DB00370MirtazapineKappa-type opioid receptortarget
DB00370MirtazapineHistamine H1 receptortarget
DB00370MirtazapineCytochrome P450 1A2enzyme
DB00370MirtazapineCytochrome P450 3A4enzyme
DB00370MirtazapineCytochrome P450 2D6enzyme
DB00370MirtazapineAlpha-1 adrenergic receptorstarget
DB00370MirtazapineSodium-dependent serotonin transportertransporter
DB00230PregabalinExcitatory amino acid transporter 3transporter
DB00230PregabalinVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00230PregabalinLarge neutral amino acids transporter small subunit 1transporter
DB00656Trazodone5-hydroxytryptamine receptor 2Atarget
DB00656TrazodoneSodium-dependent serotonin transportertarget
DB00656TrazodoneAlpha-1A adrenergic receptortarget
DB00656TrazodoneAlpha-2A adrenergic receptortarget
DB00656TrazodoneHistamine H1 receptortarget
DB00656Trazodone5-hydroxytryptamine receptor 1Atarget
DB00656TrazodoneCytochrome P450 2D6enzyme
DB00656TrazodoneCytochrome P450 3A4enzyme
DB00656Trazodone5-hydroxytryptamine receptor 2Ctarget
DB00656TrazodoneCytochrome P450 3A5enzyme
DB00656TrazodoneCytochrome P450 3A7enzyme
DB00656TrazodoneP-glycoprotein 1transporter
DB00656Trazodone5-hydroxytryptamine receptor 1Ctarget
DrugDrug NamePhaseStatusCount
DB00741Hydrocortisone0Completed1
DB15348Ampreloxetine1Completed1
DB00318Codeine1Completed1
DB06700Desvenlafaxine1Completed1
DB12395Esreboxetine1Completed1
DB00281Lidocaine1Completed1
DB04896Milnacipran1Completed1
DB00218Moxifloxacin1Completed1
DB11145Oxyquinoline1Not Yet Recruiting1
DB00715Paroxetine1Completed1
DB00321Amitriptyline1 / 2Completed1
DB00715Paroxetine1 / 2Completed1
DB00285Venlafaxine1 / 2Completed1
DB00321Amitriptyline2Completed1
DB15348Ampreloxetine2Completed1
DB12768BCG vaccine2Not Yet Recruiting1
DB06774Capsaicin2Recruiting1
DB00190Carbidopa2Completed1
DB06700Desvenlafaxine2Terminated1
DB00514Dextromethorphan2Recruiting1
DB06262Droxidopa2Completed1
DB12177Eplivanserin2Completed1
DB09119Eslicarbazepine acetate2Completed1
DB12395Esreboxetine2Completed1
DB08917Ferric carboxymaltose2Completed1
DB00472Fluoxetine2Completed1
DB14041Fremanezumab2Recruiting1
DB14009Medical Cannabis2Recruiting1
DB00331Metformin2Completed1
DB00486Nabilone2Completed1
DB00413Pramipexole2Terminated1
DB00230Pregabalin2Terminated1
DB00230Pregabalin2Unknown Status1
DB00545Pyridostigmine2Completed1
DB12143Rezatomidine2Terminated1
DB15073Ribose2Completed1
DB09072Sodium oxybate2Completed1
DB06417Somatotropin2Completed1
DB00193Tramadol2Completed1
DB00321Amitriptyline2 / 3Unknown Status1
DB06700Desvenlafaxine2 / 3Completed1
DB06700Desvenlafaxine2 / 3Terminated1
DB00996Gabapentin2 / 3Completed1
DB01065Melatonin2 / 3Unknown Status1
DB04896Milnacipran2 / 3Completed1
DB00230Pregabalin2 / 3Completed1
DB00924Cyclobenzaprine3Completed1
DB00924Cyclobenzaprine3Not Yet Recruiting1
DB00924Cyclobenzaprine3Terminated1
DB00757Dolasetron3Completed1
DB00476Duloxetine3Completed8
DB00476Duloxetine3Recruiting1
DB01175Escitalopram3Recruiting1
DB12395Esreboxetine3Withdrawn1
DB00472Fluoxetine3Completed1
DB00996Gabapentin3Completed1
DB00920Ketotifen3Completed1
DB00281Lidocaine3Unknown Status1
DB01043Memantine3Unknown Status1
DB04896Milnacipran3Completed5
DB04896Milnacipran3Terminated2
DB11825Mirogabalin3Completed1
DB00230Pregabalin3Completed14
DB00230Pregabalin3Recruiting1
DB00545Pyridostigmine3Enrolling by Invitation1
DB00234Reboxetine3Completed1
DB00234Reboxetine3Terminated2
DB09072Sodium oxybate3Completed4
DB00052Somatotropin3Completed1
DB00193Tramadol3Completed1
DB00316Acetaminophen4Completed1
DB00321Amitriptyline4Completed2
DB00083Botulinum toxin type A4Completed1
DB00924Cyclobenzaprine4Unknown Status1
DB00476Duloxetine4Completed1
DB00476Duloxetine4Withdrawn2
DB00402Eszopiclone4Completed1
DB01628Etoricoxib4Unknown Status1
DB04841Flunarizine4Recruiting1
DB00472Fluoxetine4Completed1
DB04077Glycerin4Withdrawn1
DB04896Milnacipran4Completed6
DB04896Milnacipran4Unknown Status1
DB04896Milnacipran4Withdrawn1
DB00704Naltrexone4Recruiting1
DB00230Pregabalin4Completed5
DB00230Pregabalin4Recruiting1
DB00230Pregabalin4Withdrawn1
DB01224Quetiapine4Completed3
DB00017Salmon Calcitonin4Withdrawn1
DB09034Suvorexant4Terminated1
DB00193Tramadol4Completed1
DB00656Trazodone4Completed1
DB00909Zonisamide4Withdrawn1
DB00316AcetaminophenNot AvailableCompleted1
DB06594AgomelatineNot AvailableCompleted1
DB00321AmitriptylineNot AvailableCompleted1
DB06634CasopitantNot AvailableCompleted1
DB00215CitalopramNot AvailableUnknown Status1
DB00470DronabinolNot AvailableUnknown Status1
DB00476DuloxetineNot AvailableNo Longer Available1
DB00476DuloxetineNot AvailableNot Yet Recruiting1
DB00476DuloxetineNot AvailableUnknown Status2
DB00783EstradiolNot AvailableTerminated1
DB00996GabapentinNot AvailableCompleted1
DB01202LevetiracetamNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB00603Medroxyprogesterone acetateNot AvailableTerminated1
DB00486NabiloneNot AvailableCompleted1
DB00704NaltrexoneNot AvailableCompleted1
DB00704NaltrexoneNot AvailableUnknown Status1
DB00704NaltrexoneNot AvailableWithdrawn1
DB00230PregabalinNot AvailableCompleted1
DB00230PregabalinNot AvailableNot Yet Recruiting1
DB00230PregabalinNot AvailableRecruiting2
DB00230PregabalinNot AvailableUnknown Status1
DB08839SerotoninNot AvailableUnknown Status1
DB00135TyrosineNot AvailableTerminated1