Cluster Headache

Also known as: Cluster headaches / Cluster headache / Headaches, Cluster / Ciliary neuralgia / Headache histamine / Horton's headache / Headache vasomotor / Migrainous neuralgia / Headaches cluster

DrugDrug NameDrug Description
DB00320DihydroergotamineAn ergot alkaloid used in the acute treatment of migraine headache and cluster headache.
DB00696ErgotamineA alpha-1 selective adrenergic agonist vasoconstrictor used to treat migraines with or without aura and cluster headaches.
DB00273TopiramateAn anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines.
DrugDrug NameTargetType
DB00320Dihydroergotamine5-hydroxytryptamine receptor 1Dtarget
DB00320Dihydroergotamine5-hydroxytryptamine receptor 1Btarget
DB00320DihydroergotamineCytochrome P450 3A4enzyme
DB00320DihydroergotamineAlpha-2A adrenergic receptortarget
DB00320Dihydroergotamine5-hydroxytryptamine receptor 2Btarget
DB00320DihydroergotamineP-glycoprotein 1transporter
DB00696ErgotamineAlpha-1A adrenergic receptortarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Dtarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Btarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Atarget
DB00696ErgotamineAlpha-2A adrenergic receptortarget
DB00696ErgotamineDopamine D2 receptortarget
DB00696ErgotamineAlpha-2B adrenergic receptortarget
DB00696ErgotamineSodium-dependent noradrenaline transportertarget
DB00696ErgotamineCytochrome P450 3A4enzyme
DB00696ErgotamineAlpha-1B adrenergic receptortarget
DB00696ErgotamineAlpha-1D adrenergic receptortarget
DB00696ErgotamineP-glycoprotein 1transporter
DB00696ErgotamineD(1) dopamine receptortarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Atarget
DB00696Ergotamine5-hydroxytryptamine receptor 1Ftarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Ctarget
DB00696Ergotamine5-hydroxytryptamine receptor 2Btarget
DB00273TopiramateGamma-aminobutyric acid receptor subunit alpha-1target
DB00273TopiramateSodium channel protein type 1 subunit alphatarget
DB00273TopiramateCarbonic anhydrase 2target
DB00273TopiramateCarbonic anhydrase 4target
DB00273TopiramateGlutamate receptor ionotropic, kainate 1target
DB00273TopiramateCytochrome P450 2C19enzyme
DB00273TopiramateCytochrome P450 3A4enzyme
DB00273TopiramateGABA-A receptor (anion channel)target
DB00273TopiramateCarbonic anhydrase 1target
DB00273TopiramateCarbonic anhydrase 3target
DB00273TopiramateGlutamate receptor 1target
DrugDrug NamePhaseStatusCount
DB06774Capsaicin1Active Not Recruiting1
DB09140Oxygen1Terminated1
DB11664Psilocybine1Recruiting1
DB00669Sumatriptan1Completed1
DB00083Botulinum toxin type A1 / 2Completed1
DB00083Botulinum toxin type A1 / 2Recruiting1
DB11842Angiotensin II2Completed1
DB00796Candesartan cilexetil2Completed1
DB09157Carbon dioxide2Terminated1
DB04829Lysergic acid diethylamide2Recruiting1
DB13003Cortivazol2 / 3Completed1
DB00661Verapamil2 / 3Completed1
DB00315Zolmitriptan2 / 3Recruiting1
DB00083Botulinum toxin type A3Not Yet Recruiting1
DB14041Fremanezumab3Terminated1
DB09153Sodium chloride3Not Yet Recruiting1
DB09072Sodium oxybate3Not Yet Recruiting1
DB00669Sumatriptan3Completed1
DB00273Topiramate4Terminated1
DB00315Zolmitriptan4Not Yet Recruiting1
DB06379Calcitonin gene-related peptideNot AvailableActive Not Recruiting1
DB14041FremanezumabNot AvailableAvailable1
DB00313Valproic acidNot AvailableCompleted1