Hypercalcemia

Also known as: Hypercalcaemia / Familial hypocalciuric hypercalcemia / Blood calcium increased / Calcium blood increased

DrugDrug NameDrug Description
DB01012CinacalcetA calcium sensing receptor agonist used to treat secondary hyperparathyroidism in chronic kidney disease and hypercalcemia in parathyroid carcinoma.
DB01234DexamethasoneA glucocorticoid available in various modes of administration that is used for the treatment of various inflammatory conditions, including bronchial asthma, as well as endocrine and rheumatic disorders.
DB14600Edetate disodium anhydrousA polyvalent ion chelator indicated for emergency treatment of hypercalcemia and digitalis toxicity associated ventricular arrhythmias.
DB00959MethylprednisoloneA corticosteroid used to treat inflammation or immune reactions across a variety of organ systems, endocrine conditions, and neoplastic diseases.
DB00017Salmon calcitoninA synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
DB00620TriamcinoloneA glucocorticoid used to treat a wide variety of inflammatory conditions of organ systems and tissues.
DrugDrug NameTargetType
DB01012CinacalcetExtracellular calcium-sensing receptortarget
DB01012CinacalcetCytochrome P450 3A4enzyme
DB01012CinacalcetCytochrome P450 2D6enzyme
DB01012CinacalcetCytochrome P450 1A2enzyme
DB01234DexamethasoneGlucocorticoid receptortarget
DB01234DexamethasoneAnnexin A1target
DB01234DexamethasoneNitric oxide synthase, inducibletarget
DB01234DexamethasoneNuclear receptor subfamily 0 group B member 1target
DB01234DexamethasoneCytochrome P450 3A4enzyme
DB01234DexamethasoneCytochrome P450 3A5enzyme
DB01234DexamethasoneCytochrome P450 3A7enzyme
DB01234DexamethasoneBile salt export pumptransporter
DB01234DexamethasoneP-glycoprotein 1transporter
DB01234DexamethasoneCanalicular multispecific organic anion transporter 1transporter
DB01234DexamethasoneSolute carrier organic anion transporter family member 1A2transporter
DB01234DexamethasoneATP-binding cassette sub-family G member 2transporter
DB01234DexamethasoneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB01234DexamethasoneCytochrome P450 1A1enzyme
DB01234DexamethasoneCytochrome P450 2A6enzyme
DB01234DexamethasoneCytochrome P450 2B6enzyme
DB01234DexamethasoneCytochrome P450 2C19enzyme
DB01234DexamethasoneCytochrome P450 2C8enzyme
DB01234DexamethasoneCytochrome P450 2E1enzyme
DB01234DexamethasoneCytochrome P450 3A43enzyme
DB01234DexamethasoneCytochrome P450 4A11enzyme
DB01234DexamethasoneNuclear receptor subfamily 1 group I member 2target
DB01234DexamethasoneCytochrome P450 11B1, mitochondrialenzyme
DB01234DexamethasoneSerum albumincarrier
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB01234DexamethasoneCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB01234DexamethasoneSolute carrier family 22 member 8transporter
DB14600Edetate disodium anhydrousLeadtarget
DB14600Edetate disodium anhydrousIrontarget
DB14600Edetate disodium anhydrousManganese cationtarget
DB14600Edetate disodium anhydrousAdenosine deaminaseenzyme
DB14600Edetate disodium anhydrousSerum paraoxonase/lactonase 3enzyme
DB14600Edetate disodium anhydrousCytochrome P450 19A1enzyme
DB14600Edetate disodium anhydrousCytochrome P450 3A4enzyme
DB14600Edetate disodium anhydrousSerum paraoxonase/arylesterase 1enzyme
DB00959MethylprednisoloneGlucocorticoid receptortarget
DB00959MethylprednisoloneCytochrome P450 3A4enzyme
DB00959MethylprednisoloneP-glycoprotein 1transporter
DB00959MethylprednisoloneCytochrome P450 3A Subfamilyenzyme
DB00959MethylprednisoloneCytochrome P450 2A6enzyme
DB00959MethylprednisoloneCytochrome P450 1B1enzyme
DB00959MethylprednisoloneCytochrome P450 2B6enzyme
DB00959MethylprednisoloneCytochrome P450 2C8enzyme
DB00959MethylprednisoloneCytochrome P450 2C9enzyme
DB00959MethylprednisoloneCytochrome P450 2C19enzyme
DB00959MethylprednisoloneAnnexin A1target
DB00959Methylprednisolone20-ketosteroid reductase (20-hydroxysteroid dehydrogenase)enzyme
DB00959Methylprednisolone11beta-hydroxysteroid dehydrogenaseenzyme
DB00959MethylprednisoloneSerum albumincarrier
DB00017Salmon calcitoninCalcitonin receptortarget
DB00620TriamcinoloneCorticosteroid-binding globulincarrier
DB00620TriamcinoloneGlucocorticoid receptortarget
DB00620TriamcinoloneCytochrome P450 3A4enzyme
DB00620TriamcinoloneProstaglandin G/H synthase 2enzyme
DB00620TriamcinoloneCholinesteraseenzyme
DB00620TriamcinoloneCytochrome P450 3A5enzyme
DB00620TriamcinoloneCytochrome P450 3A7enzyme
DB00620TriamcinoloneSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB01373Calcium2Completed1
DB06132Nivolumab2Completed1
DB09035Nivolumab2Completed1
DB00169Cholecalciferol2 / 3Completed1
DB11094Vitamin D2 / 3Completed1
DB01012Cinacalcet3Completed2
DB00136Calcitriol4Terminated1
DB00153Ergocalciferol4Completed1
DB00910Paricalcitol4Completed1
DB00910Paricalcitol4Terminated1
DB00017Salmon calcitonin4Recruiting1
DB11094Vitamin D4Completed1
DB01012CinacalcetNot AvailableWithdrawn1
DB00399Zoledronic acidNot AvailableCompleted1