Scabies

Also known as: Sarcoptic itch / Infestation by Sarcoptes scabiei var hominis (disorder) / Scabies infestation / Sarcoptes scabeii infestation / Acarodermatitis

Drug	Drug Name	Drug Description
DB00676	Benzyl benzoate	A topical treatment for scabies and lice.
DB00265	Crotamiton	A topical scabicidal and antipruritic agent used for scabies eradication and for the relief of pruritus.
DB00602	Ivermectin	An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
DB00431	Lindane	An ectoparasiticide and ovicide used in the treatment of Pediculosis humanis capitis (head lice) and Phthirus pubis (crab lice).
DB04930	Permethrin	An insecticide used to prevent infestation with Sarcoptes scabiei (scabies).
DB08823	Spinosad	A pediculicide used topically to treat head lice.

Drug	Drug Name	Target	Type
DB00602	Ivermectin	P-glycoprotein 1	transporter
DB00602	Ivermectin	Multidrug resistance-associated protein 1	transporter
DB00602	Ivermectin	Canalicular multispecific organic anion transporter 1	transporter
DB00602	Ivermectin	ATP-binding cassette sub-family G member 2	transporter
DB00602	Ivermectin	Cytochrome P450 3A4	enzyme
DB00602	Ivermectin	Solute carrier organic anion transporter family member 1B1	transporter
DB00602	Ivermectin	Solute carrier organic anion transporter family member 1B3	transporter
DB00602	Ivermectin	Cytochrome P450 2D6	enzyme
DB00602	Ivermectin	Cytochrome P450 2E1	enzyme
DB00431	Lindane	Gamma-aminobutyric acid receptor subunit beta-1	target
DB00431	Lindane	Glycine receptor subunit alpha-1	target
DB00431	Lindane	Glycine receptor subunit alpha-2	target
DB00431	Lindane	Glycine receptor subunit alpha-3	target
DB00431	Lindane	Glycine receptor subunit beta	target
DB00431	Lindane	Gamma-aminobutyric acid receptor subunit beta-3	target
DB00431	Lindane	Gamma-aminobutyric acid receptor subunit rho-1	target
DB00431	Lindane	Progesterone receptor	target
DB00431	Lindane	Estrogen receptor alpha	target
DB00431	Lindane	Nuclear receptor subfamily 1 group I member 2	target
DB04930	Permethrin	Cytochrome P450 2B6	enzyme
DB04930	Permethrin	Sodium channel protein type 1 subunit alpha	target
DB04930	Permethrin	Estrogen receptor alpha	target
DB04930	Permethrin	Nuclear receptor subfamily 1 group I member 2	target

Drug	Drug Name	Phase	Status	Count
DB00602	Ivermectin	1	Completed	1
DB09353	Octasulfur	1	Completed	1
DB04930	Permethrin	1	Completed	2
DB00602	Ivermectin	2	Active Not Recruiting	1
DB00602	Ivermectin	2	Completed	1
DB00602	Ivermectin	2	Recruiting	1
DB11431	Moxidectin	2	Completed	1
DB11431	Moxidectin	2	Recruiting	1
DB04930	Permethrin	2	Completed	2
DB04930	Permethrin	2	Recruiting	1
DB00518	Albendazole	3	Completed	1
DB11638	Artenimol	3	Recruiting	1
DB00207	Azithromycin	3	Completed	1
DB00711	Diethylcarbamazine	3	Completed	1
DB00602	Ivermectin	3	Completed	2
DB00602	Ivermectin	3	Recruiting	1
DB00602	Ivermectin	3	Unknown Status	1
DB00772	Malathion	3	Completed	1
DB04930	Permethrin	3	Completed	5
DB04930	Permethrin	3	Recruiting	1
DB04930	Permethrin	3	Unknown Status	1
DB13941	Piperaquine	3	Recruiting	1
DB08823	Spinosad	3	Completed	2
DB00207	Azithromycin	4	Completed	1
DB06770	Benzyl alcohol	4	Recruiting	1
DB00676	Benzyl benzoate	4	Completed	1
DB00602	Ivermectin	4	Completed	2
DB04930	Permethrin	4	Completed	2
DB08823	Spinosad	4	Recruiting	1
DB00602	Ivermectin	Not Available	Completed	3
DB04930	Permethrin	Not Available	Completed	2