Ascites

DrugDrug NameDrug Description
DB00594AmilorideA pyrizine compound used to treat hypertension and congestive heart failure.
DB00903Etacrynic acidA diuretic used to treat ascites and edema in congestive heart failure, liver cirrhosis, and renal disease.
DB00999HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DB00421SpironolactoneAn aldosterone receptor antagonist used for the treatment of hypertension, hyperaldosteronism, edema due to various conditions, hirsutism (off-label) and hypokalemia.
DrugDrug NameTargetType
DB00594AmilorideAmiloride-sensitive sodium channel subunit betatarget
DB00594AmilorideAcid-sensing ion channel 1target
DB00594AmilorideAmiloride-sensitive amine oxidase [copper-containing]target
DB00594AmilorideAmiloride-sensitive sodium channel subunit alphatarget
DB00594AmilorideAmiloride-sensitive sodium channel subunit gammatarget
DB00594AmilorideSodium/hydrogen exchanger 1target
DB00594AmilorideAcid-sensing ion channel 2target
DB00594AmilorideAmiloride-sensitive sodium channel subunit deltatarget
DB00594AmilorideUrokinase-type plasminogen activatortarget
DB00594AmilorideSolute carrier family 22 member 2transporter
DB00594AmilorideSolute carrier family 22 member 4transporter
DB00594AmilorideAmiloride-sensitive amine oxidase [copper-containing]enzyme
DB00594AmilorideAmiloride-sensitive amine oxidase [copper-containing]enzyme
DB00903Etacrynic acidSolute carrier family 12 member 1target
DB00903Etacrynic acidSodium/potassium-transporting ATPase subunit alpha-1target
DB00903Etacrynic acidGlutathione S-transferase A2enzyme
DB00903Etacrynic acidSerum albumincarrier
DB00903Etacrynic acidSolute carrier family 22 member 6transporter
DB00903Etacrynic acidLymphoid enhancer-binding factor 1target
DB00903Etacrynic acidGlutathione S-transferase Ptarget
DB00999HydrochlorothiazideSolute carrier family 12 member 3target
DB00999HydrochlorothiazideSolute carrier family 22 member 6transporter
DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
DB00999HydrochlorothiazideSerum albumincarrier
DB00999HydrochlorothiazideSolute carrier family 22 member 11transporter
DB00999HydrochlorothiazideMultidrug resistance-associated protein 4transporter
DB00999HydrochlorothiazideSolute carrier family 22 member 8transporter
DB00421SpironolactoneMineralocorticoid receptortarget
DB00421SpironolactoneCytochrome P450 2C8enzyme
DB00421SpironolactoneCanalicular multispecific organic anion transporter 1transporter
DB00421SpironolactoneP-glycoprotein 1transporter
DB00421SpironolactoneSolute carrier organic anion transporter family member 1A2transporter
DB00421SpironolactoneCytochrome P450 11B1, mitochondrialenzyme
DB00421SpironolactoneAndrogen receptortarget
DB00421SpironolactoneProgesterone receptortarget
DB00421SpironolactoneGlucocorticoid receptortarget
DB00421SpironolactoneCytochrome P450 11B2, mitochondrialtarget
DB00421SpironolactoneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00421Spironolactone3-oxo-5-alpha-steroid 4-dehydrogenasetarget
DB00421SpironolactoneSex hormone-binding globulintarget
DB00421SpironolactoneVoltage-dependent calcium channeltarget
DB00421SpironolactoneNuclear receptor subfamily 1 group I member 2target
DB00421SpironolactoneBile salt export pumptransporter
DB00421SpironolactoneSerum albumincarrier
DB00421Spironolactonealpha1-acid glycoproteincarrier
DrugDrug NamePhaseStatusCount
DB06212Tolvaptan1Completed1
DB06403Ambrisentan2Recruiting1
DB14825Danvatirsen2Terminated1
DB00700Eplerenone2Withdrawn1
DB00695Furosemide2Completed1
DB00104Octreotide2Completed1
DB14923Satavaptan2Completed3
DB01268Sunitinib2Terminated1
DB06212Tolvaptan2Completed1
DB08885Aflibercept2 / 3Completed1
DB00438Ceftazidime2 / 3Terminated1
DB00080Daptomycin2 / 3Terminated1
DB00760Meropenem2 / 3Terminated1
DB02638Terlipressin2 / 3Completed1
DB02638Terlipressin2 / 3Not Yet Recruiting1
DB01059Norfloxacin3Recruiting1
DB00571Propranolol3Recruiting1
DB01220Rifaximin3Recruiting2
DB14923Satavaptan3Completed1
DB14923Satavaptan3Terminated2
DB06212Tolvaptan3Completed1
DB00062Albumin human4Completed2
DB01136Carvedilol4Completed1
DB00537Ciprofloxacin4Withdrawn1
DB00695Furosemide4Completed2
DB00678Losartan4Unknown Status1
DB00211Midodrine4Completed1
DB00104Octreotide4Completed1
DB01132Pioglitazone4Completed1
DB00571Propranolol4Completed1
DB01220Rifaximin4Completed1
DB00421Spironolactone4Completed1
DB06212Tolvaptan4Completed1
DB06212Tolvaptan4Unknown Status1
DB00062Albumin humanNot AvailableActive Not Recruiting1
DB00062Albumin humanNot AvailableSuspended1
DB00211MidodrineNot AvailableWithdrawn1