Autistic Disorder

Also known as: Autistic disorder / Disorders, Autistic / Childhood autism / Kanner's syndrome / Infantile autism / Early infantile autism / Autism infantile / Autism

DrugDrug NameDrug Description
DB00734RisperidoneSchizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical pathways, respectively [L1212, L1213]. Risperidone inhibits dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain. It is also said to block histamine receptors, and other neural receptors which are currently being studied [L1213,A1115]. Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors [L1212, L1213, A1115].
DrugDrug NamePhaseStatusCount
DB00657Mecamylamine1Completed1
DB00107Oxytocin1Active Not Recruiting1
DB12721RO-50284421Completed1
DB06151Acetylcysteine2Completed1
DB01238Aripiprazole2Completed1
DB00887Bumetanide2Withdrawn1
DB11121Chloroxylenol2Recruiting1
DB00169Cholecalciferol2Completed1
DB00215Citalopram2Completed1
DB00843Donepezil2Completed1
DB00472Fluoxetine2Completed1
DB00650Leucovorin2Terminated1
DB08815Lurasidone2Completed1
DB01043Memantine2Completed2
DB01043Memantine2Terminated1
DB00334Olanzapine2Completed1
DB02789Pregnenolone2Completed1
DB00360Sapropterin2Completed1
DB12422Sulforaphane2Recruiting2
DB00659Acamprosate2 / 3Recruiting1
DB00490Buspirone2 / 3Completed1
DB00115Cyanocobalamin2 / 3Completed1
DB03614Methylcobalamin2 / 3Completed2
DB00360Sapropterin2 / 3Completed1
DB01238Aripiprazole3Completed6
DB01238Aripiprazole3Recruiting1
DB00260Cycloserine3Completed3
DB00472Fluoxetine3Completed1
DB00472Fluoxetine3Terminated1
DB00734Risperidone3Completed2
DB01238Aripiprazole4Completed1
DB00289Atomoxetine4Completed1
DB00028Immune Globulin Human4Active Not Recruiting1
DB00734Risperidone4Completed3
DB06151AcetylcysteineNot AvailableWithdrawn1
DB00802AlfentanilNot AvailableRecruiting1
DB01238AripiprazoleNot AvailableRecruiting1
DB09020BisacodylNot AvailableCompleted1
DB00438CeftazidimeNot AvailableRecruiting1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00363ClozapineNot AvailableRecruiting1
DB00115CyanocobalaminNot AvailableCompleted1
DB01234DexamethasoneNot AvailableRecruiting1
DB00829DiazepamNot AvailableRecruiting1
DB00472FluoxetineNot AvailableCompleted1
DB01320FosphenytoinNot AvailableRecruiting1
DB01018GuanfacineNot AvailableCompleted1
DB00502HaloperidolNot AvailableRecruiting1
DB01109HeparinNot AvailableRecruiting1
DB00327HydromorphoneNot AvailableRecruiting1
DB01202LevetiracetamNot AvailableRecruiting1
DB08815LurasidoneNot AvailableRecruiting1
DB00760MeropenemNot AvailableRecruiting1
DB03614MethylcobalaminNot AvailableCompleted1
DB00422MethylphenidateNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB00683MidazolamNot AvailableRecruiting1
DB01618MolindoneNot AvailableRecruiting1
DB00295MorphineNot AvailableRecruiting1
DB00622NicardipineNot AvailableRecruiting1
DB00334OlanzapineNot AvailableRecruiting1
DB00198OseltamivirNot AvailableRecruiting1
DB00312PentobarbitalNot AvailableRecruiting1
DB00818PropofolNot AvailableRecruiting1
DB01224QuetiapineNot AvailableRecruiting1
DB00734RisperidoneNot AvailableCompleted1
DB00734RisperidoneNot AvailableRecruiting1
DB11365SennosidesNot AvailableCompleted1
DB09072Sodium oxybateNot AvailableCompleted1
DB00373TimololNot AvailableRecruiting1
DB00684TobramycinNot AvailableRecruiting1
DB00273TopiramateNot AvailableRecruiting1
DB00313Valproic AcidNot AvailableRecruiting1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableRecruiting1