Caloric Restriction

Also known as: Low caloric diet / Reduced-calorie diet / Calorie Restriction / Calorie restricted diet (finding) / Low calorie diet / Low-Calorie Diet / Decreased energy diet (regime/therapy) / Diet, Reducing / Weight reduction diet (finding) / Weight loss diet

DrugDrug NameDrug Description
DB00704NaltrexoneA narcotic antagonist used in opioid overdose.
DB01083OrlistatA reversible inhibitor of gastrointestinal lipases indicated for weight loss and weight maintenance.
DB13928SemaglutideA glucagon-like peptide 1 receptor agonist used to improve glycemic control in type 2 diabetes mellitus, treat obesity, and reduce the risk of major adverse cardiovascular events in selected adults.
DB00273TopiramateAn anticonvulsant drug used in the control of epilepsy and in the prophylaxis and treatment of migraines.
DB03229alpha-Ketoisocaproic acidAn amino acid used to manage chronic renal failure and for nutritional therapy in acute renal dysfunction.
DrugDrug NameTargetType
DB00704NaltrexoneMu-type opioid receptortarget
DB00704NaltrexoneKappa-type opioid receptortarget
DB00704NaltrexoneDelta-type opioid receptortarget
DB00704NaltrexoneUDP-glucuronosyltransferase 1-1enzyme
DB00704NaltrexoneSigma non-opioid intracellular receptor 1target
DB01083OrlistatPancreatic triacylglycerol lipasetarget
DB01083OrlistatFatty acid synthasetarget
DB01083OrlistatGastric triacylglycerol lipasetarget
DB01083OrlistatCytochrome P450 3A4enzyme
DB01083OrlistatCytosolic phospholipase A2enzyme
DB01083OrlistatSerum albumincarrier
DB01083OrlistatFatty acid synthaseenzyme
DB13928SemaglutideSerum albumincarrier
DB13928SemaglutideDipeptidyl peptidase 4enzyme
DB13928SemaglutideNeprilysinenzyme
DB13928SemaglutideGlucagon-like peptide 1 receptortarget
DB13928SemaglutideLipoprotein lipaseenzyme
DB13928SemaglutideAlpha-amylase 1enzyme
DB00273TopiramateGamma-aminobutyric acid receptor subunit alpha-1target
DB00273TopiramateVoltage-gated sodium channel alpha subunittarget
DB00273TopiramateCarbonic anhydrase 2target
DB00273TopiramateCarbonic anhydrase 4target
DB00273TopiramateKainate receptorstarget
DB00273TopiramateCytochrome P450 2C19enzyme
DB00273TopiramateCytochrome P450 3A4enzyme
DB00273TopiramateCarbonic anhydrase 1target
DB00273TopiramateCarbonic anhydrase 3target
DB00273TopiramateVoltage gated L-type calcium channeltarget
DB00273TopiramateVoltage-dependent R-type calcium channeltarget
DB00273TopiramateSerum albumincarrier
DB00273TopiramateP-glycoprotein 1transporter
DB00273Topiramate5'-AMP-activated protein kinasetransporter
DB03229alpha-Ketoisocaproic acidDeacetoxycephalosporin C synthasetarget
DB03229alpha-Ketoisocaproic acidD-2-hydroxyisocaproate dehydrogenasetarget
DrugDrug NamePhaseStatusCount
DB11172Sesame oil4Completed2
DB13944Testosterone enanthate4Completed1
DB13946Testosterone undecanoate4Completed1