Endophthalmitis

Also known as: Ophthalmitis / Eye inflammation / Eye inflammation NOS

DrugDrug NameDrug Description
DB00479AmikacinAmikacin is a semi-synthetic aminoglycoside antibiotic derived from kanamycin A. Similar to other aminoglycosides, amikacin disrupts bacterial protein synthesis by binding to the 30S ribosomal subunit of susceptible organisms. Binding interferes with mRNA binding and tRNA acceptor sites, which leads to the production of non-functional or toxic peptides. Other mechanisms not fully understood may contribute to the bactericidal effects of amikacin. Amikacin is also nephrotoxic and ototoxic [FDA label].
DrugDrug NameTargetType
DB00479Amikacin30S ribosomal protein S12target
DrugDrug NamePhaseStatusCount
DB00218Moxifloxacin2Completed1
DB00218Moxifloxacin2 / 3Not Yet Recruiting1
DB00218Moxifloxacin3Not Yet Recruiting1
DB00218Moxifloxacin3Terminated1
DB00512Vancomycin3Not Yet Recruiting1
DB01327Cefazolin4Unknown Status1
DB01190Clindamycin4Completed1
DB00668Epinephrine4Unknown Status1
DB00281Lidocaine4Unknown Status1
DB00218Moxifloxacin4Recruiting1
DB01112CefuroximeNot AvailableCompleted2
DB01044GatifloxacinNot AvailableWithdrawn1
DB01137LevofloxacinNot AvailableCompleted1
DB09153Sodium ChlorideNot AvailableCompleted1