Angioedema

Also known as: Allergic angioedema / Urticaria / Angioneurotic edema / Angioneurotic oedema / Oedema angioneurotic / Quincke's edema / Angioedemas / Edema angioneurotic / Angio-oedema / Angioedema and urticaria / Angio-edema / Oedema Quincke's / Quincke's oedema / Giant urticaria / Edema Quincke's / Urticaria giant / Giant hives / Hives giant

DrugDrug NameDrug Description
DB00748CarbinoxamineCarbinoxamine is a first generation antihistamine that competes with free histamine for binding at HA-receptor sites. This antagonizes the effects of histamine on HA-receptors, leading to a reduction of the negative symptoms brought on by histamine HA-receptor binding. The product label for carbinoxamine as an over the counter cough and cold medicine is being modified to state "do not use" in children under 4 years of age in order to prevent and reduce misuse, as many unapproved carbinoxamine-containing preparations contained inappropriate labeling, which promoted unapproved uses (including management of congestion, cough, the common cold, and the use in children under 2 years of age), which can potentially cause serious health risks.
DB00283ClemastineAn ethanolamine-derivative, first generation histamine H1 antagonist used in hay fever, rhinitis, allergic skin conditions, and pruritus. It causes drowsiness.
DB09555Dexchlorpheniramine maleateDexchlorpheniramine is the S-enantiomer of chlorpheniramine which is a 1st generation anti-histamine. Dexchlorpheniramine has more pharmacological activity than the R and so is more potent than the racemic mixture.
DB01075DiphenhydramineA histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
DrugDrug NamePhaseStatusCount
DB01380Cortisone acetate2Completed1
DB00668Epinephrine2Recruiting1
DB00741Hydrocortisone2Completed1
DB06196Icatibant2Completed1
DB00043Omalizumab2Recruiting1
DB06196Icatibant3Completed1
DB00043Omalizumab3Completed1
DB00169CholecalciferolNot AvailableCompleted1
DB01109HeparinNot AvailableCompleted1