Agitation

Also known as: Agitations / Excitement abnormal / Feeling agitated / Agitated

DrugDrug NameDrug Description
DB00543AmoxapineA tricyclic antidepressant used in the treatment of neurotic or reactive depressive disorders and endogenous or psychotic depression.
DB01238AripiprazoleAn atypical antipsychotic used in the treatment of a wide variety of mood and psychotic disorders, such as schizophrenia, bipolar I, major depressive disorder, irritability associated with autism, and Tourette's syndrome.
DB00450DroperidolA butyrophenone derivative and dopamine antagonist used to prevent and treat postoperative nausea and vomiting.
DB00186LorazepamA long-acting benzodiazepine commonly used to treat panic disorders, severe anxiety, and seizures.
DB00457PrazosinAn alpha-blocker that causes a decrease in total peripheral resistance and is used to treat hypertension.
DB00734RisperidoneA second-generation antipsychotic medication used to treat a number of mental health disorders including schizophrenia, bipolar mania, psychosis, or as an adjunct in severe depression.
DB00831TrifluoperazineA phenothiazine used to treat depression, anxiety, and agitation.
DB00246ZiprasidoneAn atypical antipsychotic used to manage schizophrenia, bipolar mania, and agitation in patients with schizophrenia.
DrugDrug NameTargetType
DB00543AmoxapineSodium-dependent serotonin transportertarget
DB00543AmoxapineSodium-dependent noradrenaline transportertarget
DB00543AmoxapineAlpha-2A adrenergic receptortarget
DB00543AmoxapineDopamine D2 receptortarget
DB00543AmoxapineAlpha-1A adrenergic receptortarget
DB00543AmoxapineDopamine D1 receptortarget
DB00543AmoxapineMuscarinic acetylcholine receptor M1target
DB00543AmoxapineGamma-aminobutyric acid receptor subunit alpha-1target
DB00543AmoxapineAlpha-1-acid glycoprotein 1carrier
DB00543AmoxapineCytochrome P450 2D6enzyme
DB00543Amoxapine5-hydroxytryptamine receptor 2Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 2Ctarget
DB00543Amoxapine5-hydroxytryptamine receptor 6target
DB00543Amoxapine5-hydroxytryptamine receptor 7target
DB00543AmoxapineDopamine D3 receptortarget
DB00543AmoxapineDopamine D4 receptortarget
DB00543AmoxapineHistamine H1 receptortarget
DB00543AmoxapineAlpha-1 adrenergic receptorstarget
DB00543AmoxapineMuscarinic acetylcholine receptortarget
DB00543Amoxapine5-hydroxytryptamine receptor 2Btarget
DB00543Amoxapine5-hydroxytryptamine receptor 3Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 1Atarget
DB00543Amoxapine5-hydroxytryptamine receptor 1Btarget
DB00543AmoxapineAlpha-2 adrenergic receptorstarget
DB00543AmoxapineHistamine H4 receptortarget
DB00543AmoxapineGABA-A receptor (anion channel)target
DB00543AmoxapineSodium-dependent dopamine transportertarget
DB01238AripiprazoleDopamine D2 receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Atarget
DB01238AripiprazoleCytochrome P450 3A4enzyme
DB01238AripiprazoleCytochrome P450 2D6enzyme
DB01238Aripiprazole5-hydroxytryptamine receptor 1Btarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Dtarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Etarget
DB01238AripiprazoleDopamine D1 receptortarget
DB01238AripiprazoleDopamine D5 receptortarget
DB01238AripiprazoleDopamine D3 receptortarget
DB01238AripiprazoleDopamine D4 receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Ctarget
DB01238Aripiprazole5-hydroxytryptamine receptor 3Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 6target
DB01238Aripiprazole5-hydroxytryptamine receptor 7target
DB01238AripiprazoleHistamine H1 receptortarget
DB01238AripiprazoleAlpha-1A adrenergic receptortarget
DB01238AripiprazoleAlpha-1B adrenergic receptortarget
DB01238AripiprazoleAlpha-2A adrenergic receptortarget
DB01238AripiprazoleAlpha-2B adrenergic receptortarget
DB01238AripiprazoleAlpha-2C adrenergic receptortarget
DB01238AripiprazoleCytochrome P450 3A5enzyme
DB01238AripiprazoleCytochrome P450 3A7enzyme
DB01238AripiprazoleSerum albumincarrier
DB01238Aripiprazole5-hydroxytryptamine receptor 2Btarget
DB01238Aripiprazole5-hydroxytryptamine receptor 5Atarget
DB01238AripiprazoleBeta-1 adrenergic receptortarget
DB01238AripiprazoleBeta-2 adrenergic receptortarget
DB01238AripiprazoleHistamine H2 receptortarget
DB01238AripiprazoleHistamine H3 receptortarget
DB01238AripiprazoleHistamine H4 receptortarget
DB01238AripiprazoleMuscarinic acetylcholine receptor M1target
DB01238AripiprazoleMuscarinic acetylcholine receptor M2target
DB01238AripiprazoleMuscarinic acetylcholine receptor M3target
DB01238AripiprazoleMuscarinic acetylcholine receptor M4target
DB01238AripiprazoleMuscarinic acetylcholine receptor M5target
DB01238AripiprazoleKappa-type opioid receptortarget
DB01238AripiprazoleMu-type opioid receptortarget
DB01238AripiprazoleDelta-type opioid receptortarget
DB01238AripiprazoleGlutamate (NMDA) receptortarget
DB01238AripiprazoleSodium-dependent dopamine transportertarget
DB01238AripiprazoleSodium-dependent serotonin transportertarget
DB00450DroperidolDopamine D2 receptortarget
DB00450DroperidolAlpha-1A adrenergic receptortarget
DB00186LorazepamTranslocator proteintarget
DB00186LorazepamUDP-glucuronosyltransferase 2B15enzyme
DB00186LorazepamGABA-A receptor (anion channel)target
DB00186LorazepamCytochrome P450 3A4enzyme
DB00457PrazosinAlpha-1A adrenergic receptortarget
DB00457PrazosinAlpha-1B adrenergic receptortarget
DB00457PrazosinAlpha-1D adrenergic receptortarget
DB00457PrazosinPotassium voltage-gated channel subfamily H member 2target
DB00457PrazosinAlpha-1-acid glycoprotein 1carrier
DB00457PrazosinSolute carrier family 22 member 1transporter
DB00457PrazosinSolute carrier family 22 member 3transporter
DB00457PrazosinP-glycoprotein 1transporter
DB00457PrazosinATP-binding cassette sub-family G member 2transporter
DB00457PrazosinAlpha-2A adrenergic receptortarget
DB00457PrazosinAlpha-2B adrenergic receptortarget
DB00457PrazosinAlpha-1 adrenergic receptorstarget
DB00734RisperidoneHistamine H1 receptortarget
DB00734RisperidoneDopamine D2 receptortarget
DB00734RisperidoneAlpha-1A adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 2Atarget
DB00734RisperidoneAlpha-1B adrenergic receptortarget
DB00734RisperidoneCytochrome P450 2D6enzyme
DB00734RisperidoneDopamine D1 receptortarget
DB00734RisperidoneAlpha-2A adrenergic receptortarget
DB00734RisperidoneAlpha-2B adrenergic receptortarget
DB00734RisperidoneAlpha-2C adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 1Atarget
DB00734Risperidone5-hydroxytryptamine receptor 1Dtarget
DB00734Risperidone5-hydroxytryptamine receptor 2Ctarget
DB00734RisperidoneDopamine D3 receptortarget
DB00734RisperidoneDopamine D4 receptortarget
DB00734RisperidoneCytochrome P450 3A4enzyme
DB00734Risperidone5-hydroxytryptamine receptor 7target
DB00734RisperidoneP-glycoprotein 1transporter
DB00831TrifluoperazineDopamine D2 receptortarget
DB00831TrifluoperazineAlpha-1A adrenergic receptortarget
DB00831TrifluoperazineNeuron-specific vesicular protein calcyontarget
DB00831TrifluoperazineXanthine dehydrogenase/oxidaseenzyme
DB00831TrifluoperazineUDP-glucuronosyltransferase 1-4enzyme
DB00831TrifluoperazineCytochrome P450 1A2enzyme
DB00831TrifluoperazineP-glycoprotein 1transporter
DB00831TrifluoperazineCalmodulintarget
DB00831TrifluoperazineTroponin C, slow skeletal and cardiac musclestarget
DB00831TrifluoperazineProtein S100-A4target
DB00246ZiprasidoneAlpha-1A adrenergic receptortarget
DB00246ZiprasidoneDopamine D2 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Ctarget
DB00246ZiprasidoneDopamine D3 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Dtarget
DB00246ZiprasidoneHistamine H1 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Atarget
DB00246ZiprasidoneDopamine D4 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 7target
DB00246ZiprasidoneCytochrome P450 3A4enzyme
DB00246ZiprasidoneAlpha-2A adrenergic receptortarget
DB00246ZiprasidoneAlpha-1B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2C adrenergic receptortarget
DB00246ZiprasidoneDopamine D1 receptortarget
DB00246ZiprasidoneDopamine D5 receptortarget
DB00246ZiprasidoneMuscarinic acetylcholine receptor M1target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M2target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M3target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M4target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M5target
DB00246Ziprasidone5-hydroxytryptamine receptor 1Btarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Etarget
DB00246Ziprasidone5-hydroxytryptamine receptor 3Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 6target
DB00246ZiprasidoneAldehyde oxidaseenzyme
DrugDrug NamePhaseStatusCount
DB00633Dexmedetomidine1Recruiting1
DB00633Dexmedetomidine2Completed1
DB00633Dexmedetomidine2Unknown Status1
DB00514Dextromethorphan2Completed1
DB00502Haloperidol2Completed1
DB14509Lithium carbonate2Recruiting1
DB04870Oleoyl-estrone2Recruiting1
DB00908Quinidine2Completed1
DB00316Acetaminophen2 / 3Completed1
DB00921Buprenorphine2 / 3Completed1
DB00633Dexmedetomidine2 / 3Recruiting1
DB00502Haloperidol2 / 3Completed1
DB00295Morphine2 / 3Completed1
DB00486Nabilone2 / 3Completed1
DB00230Pregabalin2 / 3Completed1
DB00215Citalopram3Completed1
DB00633Dexmedetomidine3Completed1
DB00633Dexmedetomidine3Recruiting1
DB00502Haloperidol3Completed1
DB00186Lorazepam3Completed1
DB00334Olanzapine3Completed1
DB01224Quetiapine3Terminated1
DB00313Valproic acid3Terminated1
DB06216Asenapine4Completed1
DB00245Benzatropine4Completed1
DB00477Chlorpromazine4Completed1
DB00633Dexmedetomidine4Completed2
DB00633Dexmedetomidine4Recruiting1
DB00633Dexmedetomidine4Unknown Status2
DB01175Escitalopram4Completed1
DB00813Fentanyl4Recruiting1
DB00502Haloperidol4Completed3
DB00502Haloperidol4Withdrawn1
DB01221Ketamine4Completed1
DB01221Ketamine4Withdrawn1
DB00186Lorazepam4Completed1
DB00653Magnesium sulfate4Unknown Status1
DB01069Promethazine4Completed1
DB00818Propofol4Completed1
DB00818Propofol4Recruiting1
DB01224Quetiapine4Completed1
DB00899Remifentanil4Completed1
DB00899Remifentanil4Unknown Status1
DB00734Risperidone4Completed3
DB00734Risperidone4Withdrawn1
DB00296Ropivacaine4Completed1
DB01236Sevoflurane4Completed1
DB00656Trazodone4Withdrawn1
DB00246Ziprasidone4Withdrawn1
DB00611ButorphanolNot AvailableRecruiting1
DB00633DexmedetomidineNot AvailableUnknown Status1
DB00813FentanylNot AvailableCompleted1
DB00502HaloperidolNot AvailableCompleted1
DB00502HaloperidolNot AvailableTerminated1
DB00683MidazolamNot AvailableCompleted1
DB00334OlanzapineNot AvailableTerminated1