Type 1 Mucopolysaccharidosis

Also known as: Mucopolysaccharidosis I / Mucopolysaccharidosis Is / Gargoylism / Mucopolysaccharidosis, type I

DrugDrug NameDrug Description
DB00090LaronidaseHuman recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human a-L-iduronidase. It contains 6 N-linked oligosaccharide modification sites.
DrugDrug NameTargetType
DB00090LaronidaseIduronic acidtarget
DrugDrug NamePhaseStatusCount
DB00030Insulin human1Active Not Recruiting1
DB00030Insulin human1Completed1
DB00090Laronidase1Terminated2
DB15336Valanafusp alfa1Active Not Recruiting1
DB15336Valanafusp alfa1Completed1
DB00051Adalimumab1 / 2Recruiting1
DB00993Azathioprine1 / 2Completed1
DB00091Cyclosporine1 / 2Completed1
DB00090Laronidase1 / 2Completed1
DB15336Valanafusp alfa1 / 2Completed2
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB01008Busulfan2Completed1
DB00531Cyclophosphamide2Completed1
DB00090Laronidase2Completed2
DB00052Somatotropin2 / 3Terminated1
DB00090Laronidase3Completed3
DB00090Laronidase4Completed2
DB00090Laronidase4Recruiting1
DB00090LaronidaseNot AvailableCompleted1
DB00090LaronidaseNot AvailableEnrolling by Invitation1