Advanced Endometrial Cancer

Drug	Drug Name	Drug Description
DB00958	Carboplatin	A alkylating agent used to treat advanced ovarian cancer.
DB00997	Doxorubicin	A medication used to treat various cancers, including AIDS-associated Kaposi's Sarcoma and metastatic cancers.
DB09037	Pembrolizumab	A PD-1 blocking antibody used to treat various types of cancer, including metastatic melanoma, non small-cell lung cancer, cervical cancer, head and neck cancer, and Hodgkin's lymphoma.

Drug	Drug Name	Target	Type
DB00958	Carboplatin	DNA	target
DB00958	Carboplatin	High affinity copper uptake protein 1	transporter
DB00958	Carboplatin	Probable low affinity copper uptake protein 2	transporter
DB00958	Carboplatin	Xanthine dehydrogenase/oxidase	enzyme
DB00958	Carboplatin	Myeloperoxidase	enzyme
DB00958	Carboplatin	Glutathione S-transferase theta-1	enzyme
DB00958	Carboplatin	Metallothionein-1A	enzyme
DB00958	Carboplatin	Metallothionein-2	enzyme
DB00958	Carboplatin	Superoxide dismutase [Cu-Zn]	enzyme
DB00958	Carboplatin	Glutathione S-transferase P	enzyme
DB00958	Carboplatin	Glutathione S-transferase Mu 1	enzyme
DB00958	Carboplatin	NAD(P)H dehydrogenase [quinone] 1	enzyme
DB00958	Carboplatin	Copper-transporting ATPase 1	transporter
DB00958	Carboplatin	Copper-transporting ATPase 2	transporter
DB00958	Carboplatin	ATP-binding cassette sub-family G member 2	transporter
DB00958	Carboplatin	Canalicular multispecific organic anion transporter 1	transporter
DB00997	Doxorubicin	DNA topoisomerase 2-alpha	target
DB00997	Doxorubicin	DNA	target
DB00997	Doxorubicin	Cytochrome P450 3A4	enzyme
DB00997	Doxorubicin	Cytochrome P450 2D6	enzyme
DB00997	Doxorubicin	Cytochrome P450 2B6	enzyme
DB00997	Doxorubicin	P-glycoprotein 1	transporter
DB00997	Doxorubicin	Canalicular multispecific organic anion transporter 2	transporter
DB00997	Doxorubicin	Multidrug resistance-associated protein 6	transporter
DB00997	Doxorubicin	Multidrug resistance-associated protein 1	transporter
DB00997	Doxorubicin	Multidrug resistance-associated protein 7	transporter
DB00997	Doxorubicin	ATP-binding cassette sub-family G member 2	transporter
DB00997	Doxorubicin	Bile salt export pump	transporter
DB00997	Doxorubicin	Solute carrier family 22 member 16	transporter
DB00997	Doxorubicin	ATP-binding cassette sub-family B member 8, mitochondrial	transporter
DB00997	Doxorubicin	Cytochrome P450 1B1	enzyme
DB00997	Doxorubicin	Carbonyl reductase [NADPH] 1	enzyme
DB00997	Doxorubicin	Carbonyl reductase [NADPH] 3	enzyme
DB00997	Doxorubicin	Alcohol dehydrogenase [NADP(+)]	enzyme
DB00997	Doxorubicin	Aldo-keto reductase family 1 member C3	enzyme
DB00997	Doxorubicin	NAD(P)H dehydrogenase [quinone] 1	enzyme
DB00997	Doxorubicin	Xanthine dehydrogenase/oxidase	enzyme
DB00997	Doxorubicin	Nitric oxide synthase, endothelial	enzyme
DB00997	Doxorubicin	Nitric oxide synthase, inducible	enzyme
DB00997	Doxorubicin	Nitric oxide synthase, brain	enzyme
DB00997	Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial	enzyme
DB00997	Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial	enzyme
DB00997	Doxorubicin	NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrial	enzyme
DB00997	Doxorubicin	NADPH--cytochrome P450 reductase	enzyme
DB00997	Doxorubicin	RalA-binding protein 1	transporter
DB00997	Doxorubicin	Canalicular multispecific organic anion transporter 1	transporter
DB00997	Doxorubicin	Serum albumin	carrier
DB00997	Doxorubicin	Nucleolar and coiled-body phosphoprotein 1	target
DB00997	Doxorubicin	DNA topoisomerase 1	target
DB00997	Doxorubicin	DNA topoisomerase 2-beta	target
DB00997	Doxorubicin	Aldose reductase	enzyme
DB00997	Doxorubicin	Aldo-keto reductase family 1 member B10	enzyme
DB00997	Doxorubicin	Aldo-keto reductase family 1 member C4	enzyme
DB09037	Pembrolizumab	Programmed cell death protein 1	target
DB09037	Pembrolizumab	Programmed cell death 1 ligand 1	target

Drug	Drug Name	Phase	Status	Count
DB17473	APL-502	2	Recruiting	2
DB11885	Anlotinib	2	Recruiting	2
DB11666	Buparlisib	2	Completed	1
DB00958	Carboplatin	2	Recruiting	1
DB01248	Docetaxel	2	Recruiting	1
DB00997	Doxorubicin	2	Recruiting	1
DB15769	Envafolimab	2	Recruiting	1
DB00441	Gemcitabine	2	Recruiting	1
DB09078	Lenvatinib	2	Not Yet Recruiting	1
DB09078	Lenvatinib	2	Recruiting	1
DB01229	Paclitaxel	2	Recruiting	1
DB09037	Pembrolizumab	2	Not Yet Recruiting	2
DB09078	Lenvatinib	3	Not Yet Recruiting	1
DB09037	Pembrolizumab	3	Not Yet Recruiting	1