Skin-structure infections

Also known as: Skin Infection / Skin Infections / Minor skin infection / Perleche / Skin infection NOS / Skin Diseases, Infectious

DrugDrug NameDrug Description
DB00355AztreonamA beta-lactam antibiotic used to treat select aztreonam sensitive gram negative bacteria.
DB00537CiprofloxacinA second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB00254DoxycyclineA tetracycline antibiotic used to treat a wide variety of bacterial infections.
DB00303ErtapenemA carbapenem antibiotic used for the treatment of moderate to severe bacterial infections caused by specific sensitive organisms.
DB14112Human vaccinia virus immune globulinA purified gamma globulin used to treat vaccinia infections where skin is compromised, or infections of the eyes, mouth, or other areas where vaccinia infections present a special hazard.
DB00218MoxifloxacinA fluoroquinolone antibiotic used to treat various bacterial infections.
DB06812Povidone-iodineA topical antiseptic agent used for the treatment and prevention of infection in wounds.
DB13503TyrothricinA topical antibiotic with broad spectrum activity against Gram positive bacteria and some fungal infections.
DrugDrug NameTargetType
DB00355AztreonamPenicillin-binding protein 3target
DB00355AztreonamBeta-lactamasetarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 2-alphatarget
DB00537CiprofloxacinCytochrome P450 1A2enzyme
DB00537CiprofloxacinCytochrome P450 3A4enzyme
DB00537CiprofloxacinCytochrome P450 3A5enzyme
DB00537CiprofloxacinCytochrome P450 3A7enzyme
DB00537CiprofloxacinP-glycoprotein 1transporter
DB00537CiprofloxacinPotassium voltage-gated channel subfamily H member 2target
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Atarget
DB00537CiprofloxacinDNA topoisomerase 4 subunit Btarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug resistance protein MdtKtarget
DB00537CiprofloxacinGyrase Atarget
DB00537CiprofloxacinDNA gyrase subunit Atarget
DB00537CiprofloxacinMultidrug and toxin extrusion protein 1transporter
DB00537CiprofloxacinMultidrug and toxin extrusion protein 2transporter
DB00537CiprofloxacinSerum albumincarrier
DB00254Doxycycline16S ribosomal RNAtarget
DB00254DoxycyclineSolute carrier family 22 member 6transporter
DB00254DoxycyclineCytochrome P450 3A4enzyme
DB00254DoxycyclineATP-binding cassette sub-family B member 5transporter
DB00303ErtapenemPenicillin-binding protein 2target
DB00303ErtapenemPeptidoglycan synthase FtsItarget
DB00303ErtapenemPenicillin-binding protein 1Atarget
DB00303ErtapenemD-alanyl-D-alanine carboxypeptidase DacCtarget
DB00303ErtapenemD-alanyl-D-alanine carboxypeptidase DacBtarget
DB00303ErtapenemPenicillin-binding protein 1Btarget
DB00303ErtapenemPeptidoglycan synthase FtsItarget
DB00303ErtapenemPenicillin-binding protein 2target
DB00218MoxifloxacinDNA gyrase subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 4 subunit Atarget
DB00218MoxifloxacinDNA topoisomerase 2-alphatarget
DB00218MoxifloxacinCytochrome P450 1A2enzyme
DB13503TyrothricinAcetylcholinesterasetarget
DB13503TyrothricinBeta-galactosidasetarget
DB13503TyrothricinPhospholipid membranetarget
DrugDrug NamePhaseStatusCount
DB12997Brilacidin2Completed1
DB12347CG-4005492Completed1
DB00080Daptomycin2Completed1
DB00254Doxycycline2Not Yet Recruiting1
DB12587Razupenem2Completed1
DB01015Sulfamethoxazole2Not Yet Recruiting1
DB00440Trimethoprim2Not Yet Recruiting1
DB01597Cilastatin3Completed1
DB00898Ethanol3Recruiting1
DB01598Imipenem3Completed1
DB00760Meropenem3Completed1
DB00626Bacitracin4Recruiting1
DB06219Dalbavancin4Recruiting1
DB00080Daptomycin4Completed1
DB14242Honey4Recruiting1
DB00512Vancomycin4Completed1