UTI caused by Escherichia coli

Also known as: Escherichia urinary tract infection

Drug	Drug Name	Drug Description
DB00537	Ciprofloxacin	A second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB00781	Polymyxin B	A polymyxin antibiotic used to treat a wide variety of infections in the body.

Drug	Drug Name	Target	Type
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 2-alpha	target
DB00537	Ciprofloxacin	Cytochrome P450 1A2	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A4	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A5	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A7	enzyme
DB00537	Ciprofloxacin	P-glycoprotein 1	transporter
DB00537	Ciprofloxacin	Potassium voltage-gated channel subfamily H member 2	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit B	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	Multidrug resistance protein MdtK	target
DB00537	Ciprofloxacin	Gyrase A	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	Multidrug and toxin extrusion protein 1	transporter
DB00537	Ciprofloxacin	Multidrug and toxin extrusion protein 2	transporter
DB00537	Ciprofloxacin	Serum albumin	carrier
DB00781	Polymyxin B	Bacterial outer membrane	target
DB00781	Polymyxin B	Solute carrier family 15 member 2	transporter

Drug	Drug Name	Phase	Status	Count