Also known as: Refractory Langerhans cell histiocytosis
DrugDrug NameDrug Description
DB00631ClofarabineClofarabine is a purine nucleoside antimetabolite that is being studied in the treatment of cancer. It is marketed in the U.S. and Canada as Clolar. In Europe and Australia/New Zealand the product is marketed under the name Evoltra. Clofarabine is used in paediatrics to treat a type of leukaemia called relapsed or refractory acute lymphoblastic leukaemia (ALL), only after at least two other types of treatment have failed. It is not known if the drug extends life expectancy. Some investigations of effectiveness in cases of acute myeloid leukaemia (AML) and juvenile myelomonocytic leukaemia (JMML) have been carried out.
DrugDrug NamePhaseStatusCount
DB12147Erdafitinib2Not Yet Recruiting1
DB12167LY-30234142Recruiting2
DB09074Olaparib2Recruiting2
DB12887Tazemetostat2Recruiting1
DB08881Vemurafenib2Recruiting1