Thromboembolism

Also known as: Thrombus / Thromboembolic event / Thromboembolism NOS / Embolism and thrombosis of unspecified site / Embolism / Embolism NOS

Drug	Drug Name	Drug Description
DB00945	Acetylsalicylic acid	A salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB01109	Heparin	An anticoagulant indicated for thromboprophylaxis and to treat thrombosis associated with a variety of conditions such as pulmonary embolism and atrial fibrillation.
DB00682	Warfarin	A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.

Drug	Drug Name	Target	Type
DB00945	Acetylsalicylic acid	Prostaglandin G/H synthase 1	target
DB00945	Acetylsalicylic acid	Prostaglandin G/H synthase 2	target
DB00945	Acetylsalicylic acid	Aldo-keto reductase family 1 member C1	target
DB00945	Acetylsalicylic acid	Solute carrier family 22 member 6	transporter
DB00945	Acetylsalicylic acid	P-glycoprotein 1	transporter
DB00945	Acetylsalicylic acid	Cytochrome P450 2C19	enzyme
DB00945	Acetylsalicylic acid	Cytochrome P450 2C9	enzyme
DB00945	Acetylsalicylic acid	5'-AMP-activated protein kinase	target
DB00945	Acetylsalicylic acid	Endothelin-1 receptor	target
DB00945	Acetylsalicylic acid	Cellular tumor antigen p53	target
DB00945	Acetylsalicylic acid	78 kDa glucose-regulated protein	target
DB00945	Acetylsalicylic acid	Ribosomal protein S6 kinase alpha-3	target
DB00945	Acetylsalicylic acid	NF-kappa-B inhibitor alpha	target
DB00945	Acetylsalicylic acid	Tumor necrosis factor-inducible gene 6 protein	target
DB00945	Acetylsalicylic acid	Caspase-1	target
DB00945	Acetylsalicylic acid	Caspase-3	target
DB00945	Acetylsalicylic acid	Inhibitor of nuclear factor kappa-B kinase subunit beta	target
DB00945	Acetylsalicylic acid	Extracellular signal-regulated kinase (ERK)	target
DB00945	Acetylsalicylic acid	G1/S-specific cyclin-D1	target
DB00945	Acetylsalicylic acid	Myc proto-oncogene protein	target
DB00945	Acetylsalicylic acid	Proliferating cell nuclear antigen	target
DB00945	Acetylsalicylic acid	Cyclin A	target
DB00945	Acetylsalicylic acid	UDP-glucuronosyltransferase 1-6	enzyme
DB00945	Acetylsalicylic acid	Arylamine N-acetyltransferase 2	enzyme
DB00945	Acetylsalicylic acid	Solute carrier family 22 member 8	transporter
DB01109	Heparin	Antithrombin-III	target
DB01109	Heparin	Coagulation factor X	target
DB01109	Heparin	P-selectin	target
DB01109	Heparin	Heparanase	enzyme
DB01109	Heparin	Fibroblast growth factor receptor 4	target
DB01109	Heparin	Fibroblast growth factor 4	target
DB01109	Heparin	Fibroblast growth factor 19	target
DB01109	Heparin	Fibroblast growth factor receptor 1	target
DB01109	Heparin	Fibroblast growth factor 1	target
DB01109	Heparin	Fibroblast growth factor receptor 2	target
DB01109	Heparin	Fibroblast growth factor 2	target
DB01109	Heparin	Platelet factor 4	target
DB01109	Heparin	Hepatocyte growth factor	target
DB01109	Heparin	Thyroxine-binding globulin	carrier
DB00682	Warfarin	Vitamin K epoxide reductase complex subunit 1	target
DB00682	Warfarin	Cytochrome P450 2C8	enzyme
DB00682	Warfarin	Cytochrome P450 1A2	enzyme
DB00682	Warfarin	Cytochrome P450 2C9	enzyme
DB00682	Warfarin	Alpha-1-acid glycoprotein 1	carrier
DB00682	Warfarin	Serum albumin	carrier
DB00682	Warfarin	Cytochrome P450 2C19	enzyme
DB00682	Warfarin	Cytochrome P450 3A4	enzyme
DB00682	Warfarin	Cytochrome P450 2C18	enzyme
DB00682	Warfarin	Nuclear receptor subfamily 1 group I member 2	target

Drug	Drug Name	Phase	Status	Count
DB06605	Apixaban	1	Recruiting	1
DB06228	Rivaroxaban	1 / 2	Completed	1
DB00945	Acetylsalicylic acid	2	Completed	1
DB03496	Alvocidib	2	Completed	1
DB12364	Betrixaban	2	Completed	1
DB00758	Clopidogrel	2	Completed	1
DB06695	Dabigatran etexilate	2	Terminated	1
DB06779	Dalteparin	2	Completed	1
DB12289	Darexaban	2	Completed	2
DB01248	Docetaxel	2	Completed	1
DB00997	Doxorubicin	2	Completed	1
DB09075	Edoxaban	2	Completed	2
DB01225	Enoxaparin	2	Completed	4
DB01196	Estramustine	2	Completed	1
DB00569	Fondaparinux	2	Completed	1
DB00441	Gemcitabine	2	Completed	1
DB01026	Ketoconazole	2	Completed	1
DB06228	Rivaroxaban	2	Completed	1
DB00682	Warfarin	2	Completed	2
DB00682	Warfarin	2	Terminated	1
DB06779	Dalteparin	2 / 3	Completed	1
DB06822	Tinzaparin	2 / 3	Completed	1
DB09261	Certoparin	3	Completed	1
DB14726	Dabigatran	3	Completed	2
DB14726	Dabigatran	3	Not Yet Recruiting	1
DB06695	Dabigatran etexilate	3	Completed	6
DB06779	Dalteparin	3	Terminated	1
DB06779	Dalteparin	3	Unknown Status	1
DB09075	Edoxaban	3	Completed	1
DB01225	Enoxaparin	3	Completed	4
DB00569	Fondaparinux	3	Completed	3
DB11728	Fondaparinux	3	Completed	2
DB00569	Fondaparinux	3	Terminated	1
DB00441	Gemcitabine	3	Terminated	1
DB01109	Heparin	3	Completed	3
DB01109	Heparin	3	Terminated	1
DB01109	Heparin	3	Unknown Status	1
DB13616	Melagatran	3	Terminated	1
DB06228	Rivaroxaban	3	Completed	2
DB12823	Tecarfarin	3	Not Yet Recruiting	1
DB00682	Warfarin	3	Completed	7
DB00682	Warfarin	3	Not Yet Recruiting	1
DB00682	Warfarin	3	Terminated	1
DB04898	Ximelagatran	3	Terminated	1
DB00945	Acetylsalicylic acid	4	Completed	1
DB00009	Alteplase	4	Completed	1
DB00009	Alteplase	4	Recruiting	1
DB06605	Apixaban	4	Recruiting	1
DB06695	Dabigatran etexilate	4	Withdrawn	1
DB06779	Dalteparin	4	Terminated	1
DB09075	Edoxaban	4	Recruiting	1
DB01225	Enoxaparin	4	Unknown Status	1
DB01109	Heparin	4	Completed	1
DB08813	Nadroparin	4	Completed	1
DB08813	Nadroparin	4	Unknown Status	1
DB06228	Rivaroxaban	4	Withdrawn	1
DB01098	Rosuvastatin	4	Completed	1
DB00936	Salicylic acid	4	Completed	1
DB06822	Tinzaparin	4	Completed	2
DB00013	Urokinase	4	Completed	1
DB00682	Warfarin	4	Completed	2
DB00945	Acetylsalicylic acid	Not Available	Completed	1
DB06605	Apixaban	Not Available	Recruiting	1
DB01225	Enoxaparin	Not Available	Completed	3
DB11728	Fondaparinux	Not Available	Completed	1
DB01109	Heparin	Not Available	Completed	1
DB09264	Idarucizumab	Not Available	Recruiting	1
DB06228	Rivaroxaban	Not Available	No Longer Available	1
DB00682	Warfarin	Not Available	Completed	1