Cardiac valve replacement

Also known as: Heart Valve Replacement / Heart valve replacement (procedure) / Heart valve replacement NOS

Drug	Drug Name	Drug Description
DB00975	Dipyridamole	A phosphodiesterase inhibitor used to prevent postoperative thromboembolic events.
DB00682	Warfarin	A vitamin K antagonist used to treat venous thromboembolism, pulmonary embolism, thromboembolism with atrial fibrillation, thromboembolism with cardiac valve replacement, and thromboembolic events post myocardial infarction.

Drug	Drug Name	Target	Type
DB00975	Dipyridamole	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	target
DB00975	Dipyridamole	cGMP-specific 3',5'-cyclic phosphodiesterase	target
DB00975	Dipyridamole	cAMP-specific 3',5'-cyclic phosphodiesterase 4A	target
DB00975	Dipyridamole	Adenosine deaminase	target
DB00975	Dipyridamole	Multidrug resistance-associated protein 4	transporter
DB00975	Dipyridamole	Multidrug resistance-associated protein 5	transporter
DB00975	Dipyridamole	P-glycoprotein 1	transporter
DB00975	Dipyridamole	Calcipressin-1	target
DB00975	Dipyridamole	Alpha-1-acid glycoprotein 1	target
DB00975	Dipyridamole	Solute carrier organic anion transporter family member 1B1	transporter
DB00975	Dipyridamole	Solute carrier organic anion transporter family member 1B3	transporter
DB00975	Dipyridamole	Solute carrier organic anion transporter family member 2B1	transporter
DB00975	Dipyridamole	Bile salt export pump	transporter
DB00682	Warfarin	Vitamin K epoxide reductase complex subunit 1	target
DB00682	Warfarin	Cytochrome P450 2C8	enzyme
DB00682	Warfarin	Cytochrome P450 1A2	enzyme
DB00682	Warfarin	Cytochrome P450 2C9	enzyme
DB00682	Warfarin	Alpha-1-acid glycoprotein 1	carrier
DB00682	Warfarin	Serum albumin	carrier
DB00682	Warfarin	Cytochrome P450 2C19	enzyme
DB00682	Warfarin	Cytochrome P450 3A4	enzyme
DB00682	Warfarin	Cytochrome P450 2C18	enzyme
DB00682	Warfarin	Nuclear receptor subfamily 1 group I member 2	target

Drug	Drug Name	Phase	Status	Count
DB00016	Erythropoietin	1 / 2	Terminated	1
DB00682	Warfarin	Not Available	Unknown Status	1