Painful musculoskeletal conditions

Also known as: Orthopaedic Related Pain (Musculoskeletal Pain) / Musculoskeletal Pain Disorder / Pain, Musculoskeletal / Musculoskeletal Pain / Rheumatic pain

DrugDrug NameDrug Description
DB06774CapsaicinCapsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements. Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations. The most recent capsaicin FDA approval was Qutenza, an 8% capsaicin patch dermal-delivery system, indicated for neuropathic pain associated with post-herpetic neuralgia.
DB00924CyclobenzaprineCyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. Cyclobenzaprine acts on the locus coeruleus where it results in increased norepinephrine release, potentially through the gamma fibers which innervate and inhibit the alpha motor neurons in the ventral horn of the spinal cord. It is structurally similar to Amitriptyline, differing by only one double bond.
DrugDrug NamePhaseStatusCount
DB00316Acetaminophen0Withdrawn1
DB00956Hydrocodone0Withdrawn1
DB11228Methylcellulose0Withdrawn1
DB00482Celecoxib1Completed1
DB00586Diclofenac1Not Yet Recruiting1
DB01009Ketoprofen1Completed1
DB00316Acetaminophen2Recruiting1
DB00318Codeine2Recruiting1
DB00956Hydrocodone2Recruiting1
DB01050Ibuprofen2Recruiting1
DB00497Oxycodone2Recruiting1
DB02789Pregnenolone2Active Not Recruiting1
DB00924Cyclobenzaprine3Not Yet Recruiting1
DB01009Ketoprofen3Completed1
DB01009Ketoprofen3Not Yet Recruiting2
DB12335Tanezumab3Recruiting1
DB00316Acetaminophen4Completed2
DB00297Bupivacaine4Completed1
DB00297Bupivacaine4Not Yet Recruiting1
DB09214Dexketoprofen4Completed2
DB01221Ketamine4Not Yet Recruiting1
DB01002Levobupivacaine4Recruiting1
DB00281Lidocaine4Completed1
DB01283Lumiracoxib4Completed1
DB09153Sodium chloride4Recruiting1