Prophylaxis of preeclampsia

Also known as: Pre-eclampsia / Toxemia of pregnancy / Pre Eclampsia / Unspecified pre-eclampsia, unspecified trimester / Toxaemia of pregnancy / Pre-eclamptic toxaemia / Pre-eclampsia toxaemia / Pre-eclampsia toxemia

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB00999HydrochlorothiazideA thiazide diuretic used to treat edema associated with a number of conditions, and hypertension.
DB00653Magnesium sulfateA drug used to treat convulsions during pregnancy, nephritis in children, magnesium deficiency, and tetany.
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00999HydrochlorothiazideSolute carrier family 12 member 3target
DB00999HydrochlorothiazideSolute carrier family 22 member 6transporter
DB00999HydrochlorothiazideCalcium-activated potassium channel subunit alpha-1target
DB00999HydrochlorothiazideSerum albumincarrier
DB00999HydrochlorothiazideSolute carrier family 22 member 11transporter
DB00999HydrochlorothiazideMultidrug resistance-associated protein 4transporter
DB00999HydrochlorothiazideSolute carrier family 22 member 8transporter
DB00653Magnesium sulfateVoltage-dependent calcium channel gamma-1 subunittarget
DB00653Magnesium sulfateVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Ctarget
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-1target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit beta-2target
DB00653Magnesium sulfateVoltage-dependent L-type calcium channel subunit alpha-1Starget
DrugDrug NamePhaseStatusCount
DB05794Serelaxin1Suspended1
DB00126Ascorbic acid1 / 2Completed1
DB06755Beta carotene1 / 2Completed1
DB00121Biotin1 / 2Completed1
DB01373Calcium1 / 2Completed1
DB00169Cholecalciferol1 / 2Completed1
DB09129Chromic chloride1 / 2Completed1
DB11134Cupric oxide1 / 2Completed1
DB00115Cyanocobalamin1 / 2Completed1
DB14491Ferrous fumarate1 / 2Completed1
DB00158Folic acid1 / 2Completed1
DB14513Magnesium1 / 2Completed1
DB00653Magnesium sulfate1 / 2Completed1
DB06757Manganese1 / 2Completed1
DB02701Nicotinamide1 / 2Completed1
DB01783Pantothenic acid1 / 2Completed1
DB06715Potassium Iodide1 / 2Completed1
DB00165Pyridoxine1 / 2Completed1
DB00140Riboflavin1 / 2Completed1
DB11068Selenic acid1 / 2Completed1
DB14496Sodium molybdate1 / 2Completed1
DB00152Thiamine1 / 2Completed1
DB00162Vitamin A1 / 2Completed1
DB01593Zinc1 / 2Completed1
DB14003alpha-Tocopherol acetate1 / 2Completed1
DB00945Acetylsalicylic acid2Recruiting1
DB01373Calcium2Completed1
DB00390Digoxin2Completed1
DB00076Digoxin Immune Fab (Ovine)2Completed1
DB00055Drotrecogin alfa2Completed1
DB01275Hydralazine2Completed1
DB00598Labetalol2Completed1
DB00175Pravastatin2Recruiting1
DB00203Sildenafil2Terminated1
DB00945Acetylsalicylic acid2 / 3Recruiting1
DB00155Citrulline2 / 3Recruiting1
DB00633Dexmedetomidine2 / 3Completed1
DB04465Lactose2 / 3Recruiting1
DB00945Acetylsalicylic acid3Not Yet Recruiting1
DB00945Acetylsalicylic acid3Terminated1
DB00125Arginine3Completed1
DB01076Atorvastatin3Completed1
DB01373Calcium3Completed1
DB00736Esomeprazole3Recruiting1
DB00999Hydrochlorothiazide3Recruiting1
DB00281Lidocaine3Withdrawn1
DB00653Magnesium sulfate3Completed1
DB00929Misoprostol3Completed1
DB00296Ropivacaine3Completed1
DB00316Acetaminophen4Active Not Recruiting1
DB00316Acetaminophen4Completed1
DB00945Acetylsalicylic acid4Completed3
DB00207Azithromycin4Recruiting1
DB01364Ephedrine4Recruiting1
DB01050Ibuprofen4Active Not Recruiting1
DB01050Ibuprofen4Completed1
DB00598Labetalol4Recruiting1
DB00968Methyldopa4Recruiting1
DB01115Nifedipine4Recruiting1
DB00388Phenylephrine4Recruiting1
DB00899Remifentanil4Unknown Status1
DB00125ArginineNot AvailableCompleted1
DB00297BupivacaineNot AvailableRecruiting1
DB01364EphedrineNot AvailableRecruiting1
DB00736EsomeprazoleNot AvailableRecruiting1
DB00813FentanylNot AvailableRecruiting1
DB06789Hydroxyprogesterone caproateNot AvailableWithdrawn1
DB00653Magnesium sulfateNot AvailableCompleted2
DB00653Magnesium sulfateNot AvailableEnrolling by Invitation1
DB00653Magnesium sulfateNot AvailableNot Yet Recruiting1
DB00331MetforminNot AvailableRecruiting1
DB00968MethyldopaNot AvailableCompleted1
DB00929MisoprostolNot AvailableNot Yet Recruiting1
DB01115NifedipineNot AvailableCompleted1
DB00393NimodipineNot AvailableCompleted1
DB00107OxytocinNot AvailableNot Yet Recruiting1
DB00107OxytocinNot AvailableRecruiting1
DB00396ProgesteroneNot AvailableWithdrawn1