Prophylaxis of radiation therapy induced nausea and vomiting

Also known as: Prophylaxis against radiation induced nausea and vomiting / Prophylaxis of radiation induced nausea and vomiting / Prophylaxis of nausea and vomiting

Drugs
Drugs and Targets

Drug	Drug Name	Drug Description
DB00985	Dimenhydrinate	A medication used to prevent and treat nausea, vomiting, vertigo, and motion sickness.
DB01233	Metoclopramide	An antiemetic agent and dopamine D2 antagonist used in the treatment of gastroesophageal reflux disease, prevention of nausea and vomiting, and to stimulate gastric emptying.
DB00904	Ondansetron	A serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting in cancer chemotherapy and postoperatively.

Drug	Drug Name	Target	Type
DB00985	Dimenhydrinate	Histamine H1 receptor	target
DB01233	Metoclopramide	Muscarinic acetylcholine receptor M1	target
DB01233	Metoclopramide	Dopamine D2 receptor	target
DB01233	Metoclopramide	Cytochrome P450 2D6	enzyme
DB01233	Metoclopramide	5-hydroxytryptamine receptor 4	target
DB01233	Metoclopramide	5-hydroxytryptamine receptor 3A	target
DB01233	Metoclopramide	Cytochrome P450 3A4	enzyme
DB01233	Metoclopramide	Cytochrome P450 1A2	enzyme
DB01233	Metoclopramide	P-glycoprotein 1	transporter
DB01233	Metoclopramide	Alpha-1-acid glycoprotein 1	carrier
DB00904	Ondansetron	5-hydroxytryptamine receptor 3A	target
DB00904	Ondansetron	Cytochrome P450 3A4	enzyme
DB00904	Ondansetron	Cytochrome P450 1A2	enzyme
DB00904	Ondansetron	Cytochrome P450 2D6	enzyme
DB00904	Ondansetron	Cytochrome P450 3A5	enzyme
DB00904	Ondansetron	Cytochrome P450 3A7	enzyme
DB00904	Ondansetron	5-hydroxytryptamine receptor 4	target
DB00904	Ondansetron	5-hydroxytryptamine receptor 1A	target
DB00904	Ondansetron	5-hydroxytryptamine receptor 1B	target
DB00904	Ondansetron	Mu-type opioid receptor	target
DB00904	Ondansetron	Cytochrome P450 2C9	enzyme
DB00904	Ondansetron	Cytochrome P450 2E1	enzyme

Drug	Drug Name	Phase	Status	Count