One to five years postmenopausal

Also known as: Post-Menopausal / Postmenopause / Postmenopausal

DrugDrug NameDrug Description
DB05084AbaloparatideA parathyroid hormone-related protein (PTHrP) analog used for the treatment of osteoporosis in postmenopausal women with a high risk of fracture.
DB00630Alendronic acidA bisphosphonate drug that prevents osteoclastic bone resorption and is used for the prevention and treatment of osteoporosis.
DB00286Conjugated estrogensA mixture of estrogens used in estrogen replacement therapy for menopause and hypoestrogenism, used in the treatment of various malignancies, and used in the treatment of postmenopausal osteoporosis.
DB06643DenosumabA RANK ligand (RANKL) inhibitor used for the management of osteoporosis in patients at high risk for bone fractures.
DB00990ExemestaneAn aromatase inhibitor used to treat breast cancer in postmenopausal women after treatment with tamoxifen.
DB00947FulvestrantAn estrogen receptor antagonist used to treat HR+ breast cancer that may also be HER2-.
DB01259LapatinibAn antineoplastic agent and tyrosine kinase inhibitor used for the treatment of advanced or metastatic HER-negative breast cancer in patients who received prior chemotherapeutic treatments.
DB01006LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
DB09073PalbociclibAn endocrine-based chemotherapeutic agent used in combination with other antineoplastic agents to treat HER2-negative and HR-positive advanced or metastatic breast cancer.
DB00396ProgesteroneA hormone used for a variety of functions, including contraception, control of abnormal uterine bleeding, maintenance of pregnancy, and prevention of endometrial hyperplasia.
DB11730RibociclibA kinase inhibitor used to treat HR+, HER2- advanced or metastatic breast cancer.
DB00884Risedronic acidA bisphosphonate used to treat osteoporosis and Paget's disease.
DB00017Salmon CalcitoninA synthetic peptide form of calcitonin used to inhibit bone resorption in the treatment of hypercalcemia, osteoporosis, and Paget's disease.
DB00539ToremifeneA first generation nonsteroidal selective estrogen receptor modulator used to treat certain breast cancers.
DB00285VenlafaxineA selective serotonin and norepinephrine reuptake inhibitor (SNRI) used for the treatment of major depression.
DrugDrug NameTargetType
DB05084AbaloparatideParathyroid hormone/parathyroid hormone-related peptide receptortarget
DB00630Alendronic acidFarnesyl pyrophosphate synthasetarget
DB00630Alendronic acidTyrosine-protein phosphatase non-receptor type 4target
DB00630Alendronic acidReceptor-type tyrosine-protein phosphatase Starget
DB00630Alendronic acidReceptor-type tyrosine-protein phosphatase epsilontarget
DB00630Alendronic acidV-type proton ATPase catalytic subunit Atarget
DB00630Alendronic acidHydroxylapatitetarget
DB00286Conjugated estrogensEstrogen receptor alphatarget
DB00286Conjugated estrogensCytochrome P450 3A4enzyme
DB00286Conjugated estrogensCytochrome P450 1A2enzyme
DB00286Conjugated estrogensCatechol O-methyltransferaseenzyme
DB00286Conjugated estrogensCanalicular multispecific organic anion transporter 2transporter
DB00286Conjugated estrogensMultidrug resistance-associated protein 4transporter
DB00286Conjugated estrogensMultidrug resistance-associated protein 1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1A2transporter
DB00286Conjugated estrogensSodium/bile acid cotransportertransporter
DB00286Conjugated estrogensSolute carrier family 22 member 10transporter
DB00286Conjugated estrogensSolute carrier family 22 member 8transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1C1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1B1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 2B1transporter
DB00286Conjugated estrogensP-glycoprotein 1transporter
DB00286Conjugated estrogensSolute carrier family 22 member 6transporter
DB00286Conjugated estrogensOrganic solute transporter subunit alphatransporter
DB00286Conjugated estrogensOrganic solute transporter subunit betatransporter
DB00286Conjugated estrogensCanalicular multispecific organic anion transporter 1transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 4A1transporter
DB00286Conjugated estrogensATP-binding cassette sub-family C member 11transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 1B3transporter
DB00286Conjugated estrogensSolute carrier family 22 member 11transporter
DB00286Conjugated estrogensSolute carrier organic anion transporter family member 3A1transporter
DB00286Conjugated estrogensATP-binding cassette sub-family G member 2transporter
DB00286Conjugated estrogensThyroxine-binding globulincarrier
DB00286Conjugated estrogensSex hormone-binding globulincarrier
DB00286Conjugated estrogensSerum albumincarrier
DB00286Conjugated estrogensEstrogen receptor betatarget
DB06643DenosumabTumor necrosis factor ligand superfamily member 11target
DB00990ExemestaneCytochrome P450 19A1target
DB00990ExemestaneCytochrome P450 3A4enzyme
DB00990ExemestaneCytochrome P450 19A1enzyme
DB00947FulvestrantEstrogen receptor alphatarget
DB00947FulvestrantCytochrome P450 3A4enzyme
DB00947FulvestrantUDP-glucuronosyltransferase 1-1enzyme
DB01259LapatinibEpidermal growth factor receptortarget
DB01259LapatinibReceptor tyrosine-protein kinase erbB-2target
DB01259LapatinibCytochrome P450 3A4enzyme
DB01259LapatinibCytochrome P450 2C8enzyme
DB01259LapatinibP-glycoprotein 1transporter
DB01259LapatinibAntigen peptide transporter 1transporter
DB01259LapatinibCytochrome P450 3A5enzyme
DB01259LapatinibCytochrome P450 2C19enzyme
DB01006LetrozoleCytochrome P450 19A1target
DB01006LetrozoleCytochrome P450 3A4enzyme
DB01006LetrozoleCytochrome P450 2A6enzyme
DB01006LetrozoleCytochrome P450 19A1enzyme
DB09073PalbociclibCyclin-dependent kinase 4target
DB09073PalbociclibCyclin-dependent kinase 6target
DB09073PalbociclibCytochrome P450 3A4enzyme
DB09073PalbociclibBile salt sulfotransferaseenzyme
DB09073PalbociclibP-glycoprotein 1transporter
DB09073PalbociclibATP-binding cassette sub-family G member 2transporter
DB09073PalbociclibSerum albumincarrier
DB09073PalbociclibSolute carrier family 22 member 1transporter
DB00396ProgesteroneProgesterone receptortarget
DB00396ProgesteroneEstrogen receptor alphatarget
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB00396ProgesteroneCytochrome P450 2C19enzyme
DB00396ProgesteroneCytochrome P450 2C9enzyme
DB00396ProgesteroneCytochrome P450 3A4enzyme
DB00396ProgesteroneCytochrome P450 3A5enzyme
DB00396ProgesteroneCytochrome P450 3A7enzyme
DB00396ProgesteroneP-glycoprotein 1transporter
DB00396ProgesteroneSolute carrier family 22 member 2transporter
DB00396ProgesteroneSolute carrier family 22 member 1transporter
DB00396ProgesteroneSolute carrier family 22 member 3transporter
DB00396ProgesteroneBile salt export pumptransporter
DB00396ProgesteroneMultidrug resistance-associated protein 1transporter
DB00396ProgesteroneSodium/bile acid cotransportertransporter
DB00396ProgesteroneSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB00396ProgesteroneCytochrome P450 1A1enzyme
DB00396ProgesteroneCytochrome P450 1B1enzyme
DB00396ProgesteroneCytochrome P450 2A6enzyme
DB00396ProgesteroneCytochrome P450 2D6enzyme
DB00396ProgesteroneMineralocorticoid receptortarget
DB00396ProgesteroneKappa-type opioid receptortarget
DB00396ProgesteroneAlpha-1-acid glycoprotein 1target
DB00396ProgesteroneGlucocorticoid receptortarget
DB00396ProgesteroneAndrogen receptortarget
DB00396ProgesteroneSex hormone-binding globulintarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B1transporter
DB00396ProgesteroneATP-binding cassette sub-family G member 2transporter
DB00396ProgesteroneEstrogen receptor betatarget
DB00396ProgesteroneSolute carrier organic anion transporter family member 1B3transporter
DB11730RibociclibCyclin-dependent kinase 4target
DB11730RibociclibCyclin-dependent kinase 6target
DB11730RibociclibCytochrome P450 3A4enzyme
DB00884Risedronic acidFarnesyl pyrophosphate synthasetarget
DB00884Risedronic acidHydroxylapatitetarget
DB00884Risedronic acidProstaglandin G/H synthase 2enzyme
DB00017Salmon CalcitoninCalcitonin receptortarget
DB00539ToremifeneEstrogen receptor alphatarget
DB00539ToremifeneCytochrome P450 3A4enzyme
DB00539ToremifeneP-glycoprotein 1transporter
DB00539ToremifeneCytochrome P450 1A1enzyme
DB00539ToremifeneSex hormone-binding globulintarget
DB00285VenlafaxineSodium-dependent serotonin transportertarget
DB00285VenlafaxineSodium-dependent noradrenaline transportertarget
DB00285VenlafaxineCytochrome P450 2D6enzyme
DB00285VenlafaxineCytochrome P450 3A4enzyme
DB00285VenlafaxineSodium-dependent dopamine transportertarget
DB00285VenlafaxineP-glycoprotein 1transporter
DB00285VenlafaxineATP-binding cassette sub-family G member 2transporter
DrugDrug NamePhaseStatusCount
DB06401Bazedoxifene1Completed3
DB00286Conjugated estrogens1Completed8
DB06643Denosumab1Terminated1
DB00783Estradiol1Completed1
DB00005Etanercept1Terminated1
DB01590Everolimus1Active Not Recruiting1
DB01006Letrozole1Active Not Recruiting1
DB00603Medroxyprogesterone acetate1Completed3
DB00884Risedronic acid1Completed1
DB11866Romosozumab1Completed1
DB05255Ronacaleret1Completed1
DB00877Sirolimus1Active Not Recruiting1
DB00072Trastuzumab1Active Not Recruiting1
DB12483Copanlisib1 / 2Not Yet Recruiting1
DB12483Copanlisib1 / 2Suspended1
DB00783Estradiol1 / 2Completed1
DB00947Fulvestrant1 / 2Not Yet Recruiting1
DB01611Hydroxychloroquine1 / 2Recruiting1
DB01006Letrozole1 / 2Not Yet Recruiting1
DB01006Letrozole1 / 2Recruiting1
DB01006Letrozole1 / 2Suspended1
DB09073Palbociclib1 / 2Recruiting1
DB09073Palbociclib1 / 2Suspended1
DB00396Progesterone1 / 2Completed1
DB11730Ribociclib1 / 2Not Yet Recruiting1
DB00072Trastuzumab1 / 2Not Yet Recruiting1
DB05812Abiraterone2Completed1
DB05220Alisertib2Recruiting1
DB14336Angelica sinensis root2Completed1
DB00125Arginine2Completed1
DB06680Asoprisnil2Completed2
DB01076Atorvastatin2Completed1
DB06401Bazedoxifene2Recruiting1
DB13975Black cohosh2Completed1
DB01156Bupropion2Recruiting1
DB00286Conjugated estrogens2Completed4
DB00286Conjugated estrogens2Recruiting1
DB01395Drospirenone2Completed1
DB00783Estradiol2Completed3
DB00990Exemestane2Active Not Recruiting1
DB00990Exemestane2Completed1
DB00990Exemestane2Recruiting1
DB00947Fulvestrant2Recruiting1
DB01645Genistein2Completed1
DB00619Imatinib2Completed1
DB01006Letrozole2Active Not Recruiting1
DB01006Letrozole2Completed1
DB01006Letrozole2Recruiting1
DB01006Letrozole2Unknown Status1
DB00007Leuprolide2Completed1
DB00603Medroxyprogesterone acetate2Completed1
DB00331Metformin2Completed1
DB06226Nelipepimut-S2Active Not Recruiting1
DB00107Oxytocin2Completed1
DB09073Palbociclib2Recruiting1
DB09037Pembrolizumab2Recruiting1
DB00860Prednisolone2Completed1
DB00635Prednisone2Completed1
DB11787Ralimetinib2Terminated1
DB00481Raloxifene2Completed1
DB11730Ribociclib2Active Not Recruiting1
DB00884Risedronic acid2Completed1
DB00020Sargramostim2Active Not Recruiting1
DB00675Tamoxifen2Terminated1
DB08867Ulipristal2Completed1
DB00783Estradiol2 / 3Completed1
DB00126Ascorbic acid3Completed1
DB06401Bazedoxifene3Completed1
DB06401Bazedoxifene3Terminated1
DB00112Bevacizumab3Active Not Recruiting1
DB01373Calcium3Completed1
DB00286Conjugated estrogens3Completed2
DB01395Drospirenone3Completed2
DB00378Dydrogesterone3Completed2
DB00783Estradiol3Completed10
DB12007Isoflavone3Unknown Status1
DB01006Letrozole3Active Not Recruiting1
DB01006Letrozole3Completed1
DB00603Medroxyprogesterone acetate3Completed3
DB00717Norethisterone3Completed1
DB01708Prasterone3Not Yet Recruiting1
DB00396Progesterone3Completed3
DB00481Raloxifene3Terminated1
DB00017Salmon Calcitonin3Completed1
DB00675Tamoxifen3Active Not Recruiting1
DB11094Vitamin D3Completed1
DB00163Vitamin E3Completed1
DB00399Zoledronic acid3Completed1
DB01217Anastrozole4Withdrawn1
DB00286Conjugated estrogens4Completed1
DB01395Drospirenone4Completed1
DB00783Estradiol4Completed6
DB00990Exemestane4Withdrawn1
DB01006Letrozole4Withdrawn1
DB00396Progesterone4Completed3
DB00675Tamoxifen4Withdrawn1
DB09070Tibolone4Completed1
DB00539Toremifene4Withdrawn1
DB13129Trimegestone4Completed1
DB01395DrospirenoneNot AvailableCompleted1
DB00783EstradiolNot AvailableCompleted4
DB00783EstradiolNot AvailableTerminated1
DB05829Parathyroid hormoneNot AvailableCompleted1
DB00396ProgesteroneNot AvailableCompleted1
DB00396ProgesteroneNot AvailableTerminated1