Glucocorticoid therapy

Also known as: Glucocorticoids / Steroids / Steroid therapy / Glucocorticoid / Corticosteroid use / Corticosteriod use / Corticosteroid therapy / Steroid therapy NOS / Adrenocortical steroid therapy

DrugDrug NameDrug Description
DB00232MethyclothiazideA thiazide diuretic with properties similar to those of hydrochlorothiazide. (From Martindale, The Extra Pharmacopoeia, 30th ed, p825)
DB00621OxandroloneA synthetic hormone with anabolic and androgenic properties.
DB00884Risedronic acidAlendronic acid is a bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959]. It functions by preventing resorption of bone[FDA Label][A959].
DB00384TriamtereneTriamterene (2,4,7-triamino-6-phenylpteridine) is a potassium-sparing diuretic that is used in the management of hypertension. It works by promoting the excretion of sodium ions and water while decreasing the potassium excretion in the distal part of the nephron in the kidneys by working on the lumenal side.[A177985] Since it acts on the distal nephron where only a small fraction of sodium ion reabsorption occurs, triamterene is reported to have limited diuretic efficacy.[T28] Due to its effects on increased serum potassium levels, triamterene is associated with a risk of producing hyperkalemia. Triamterene is a weak antagonist of folic acid, and a photosensitizing drug.[L6163] Triamterene was approved by the Food and Drug Administration in the U.S. in 1964.[L6163] Currently, triamterene is used in the treatment of edema associated with various conditions as monotherapy and is approved for use with other diuretics to enhance diuretic and potassium-sparing effects.[label] It is also found in a combination product with hydrochlorothiazide that is used for the management of hypertension or treatment of edema in patients who develop hypokalemia on hydrochlorothiazide alone.
DB00399Zoledronic acidZoledronate (zoledronic acid, marketed by Novartis under the trade names Zometa and Reclast) is a bisphosphonate. Zometa is used to prevent skeletal fractures in patients with cancers such as multiple myeloma and prostate cancer. It can also be used to treat hypercalcemia of malignancy and can be helpful for treating pain from bone metastases. An annual dose of Zoledronate may also prevent recurring fractures in patients with a previous hip fracture. Zoledronate is a single 5 mg infusion for the treatment of Paget's disease of bone. In 2007, the FDA also approved Reclast for the treatment of postmenopausal osteoporosis.
DrugDrug NamePhaseStatusCount
DB01234Dexamethasone2Completed1
DB00834Mifepristone2Completed1
DB00421Spironolactone2Completed1
DB00959Methylprednisolone3Recruiting1
DB11644Tafamidis3Recruiting1
DB01234Dexamethasone4Completed1
DB00860Prednisolone4Completed1
DB00331MetforminNot AvailableRecruiting1
DB00635PrednisoneNot AvailableNot Yet Recruiting2