Opiate withdrawal symptoms

Also known as: Opiate withdrawal / Opioid Withdrawal / Drug withdrawal syndrome / Drug withdrawal

DrugDrug NameDrug Description
DB01563Chloral hydrateA hypnotic and sedative used in the treatment of insomnia. The safety margin is too narrow for chloral hydrate to be used as a general anesthetic in humans, but it is commonly used for that purpose in animal experiments. It is no longer considered useful as an anti-anxiety medication.
DB00575ClonidineClonidine, an imidazoline-derivative hypotensive agent is a centrally-acting α2-adrenergic agonist. It crosses the blood-brain barrier and acts in the hypothalamus to induce a decrease in blood pressure. It may also be administered as an epidural infusion as an adjunct treatment in the management of severe cancer pain that is not relieved by opiate analgesics alone. Clonidine may be used for differential diagnosis of pheochromocytoma in hypertensive patients. Other uses for clonidine include prophylaxis of vascular migraine headaches, treatment of severe dysmenorrhea, management of vasomotor symptoms associated with menopause, rapid detoxification in the management of opiate withdrawal, treatment of alcohol withdrawal used in conjunction with benzodiazepines, management of nicotine dependence, topical use to reduce intraocular pressure in the treatment of open-angle and secondary glaucoma and hemorrhagic glaucoma associated with hypertension, and in the treatment of attention-deficit hyperactivity disorder (ADHD). Clonidine also exhibits some peripheral activity.
DrugDrug NamePhaseStatusCount
DB00921Buprenorphine0Completed1
DB00107Oxytocin1 / 2Enrolling by Invitation1
DB00921Buprenorphine2Completed1
DB00996Gabapentin2Completed1
DB01183Naloxone2Completed1
DB09034Suvorexant2Not Yet Recruiting1
DB00921Buprenorphine3Not Yet Recruiting1
DB04948Lofexidine3Completed1
DB00295Morphine3Not Yet Recruiting1
DB01183Naloxone3Not Yet Recruiting1
DB00193Tramadol3Not Yet Recruiting1
DB12537Benzodiazepine4Recruiting1
DB00921Buprenorphine4Completed1
DB00575Clonidine4Completed1
DB00575Clonidine4Recruiting1
DB00465Ketorolac4Recruiting1
DB00836Loperamide4Recruiting1
DB01233Metoclopramide4Recruiting1
DB00230Pregabalin4Recruiting1
DB00295MorphineNot AvailableCompleted1
DB01183NaloxoneNot AvailableCompleted1
DB00904OndansetronNot AvailableCompleted1