Recurrent, IV-B Cervical cancer

Also known as: Cervical cancer stage IV / Metastatic Cervical Cancer / Stage IV Cervical Cancer / Carcinoma uterine cervix stage IV / Ca cervix stage IV / Cervix uteri cancer stage IV / Carcinoma uterine cerix stage IV / Cervical carcinoma stage IV / Cervix carcinoma stage IV / Carcinoma cervix stage IV

DrugDrug NameDrug Description
DB00112BevacizumabA monoclonal anti-vascular endothelial growth factor antibody used in the treatment of many cancer types in combination with other antineoplastics.
DB00762IrinotecanAn antineoplastic enzyme inhibitor used to treat metastatic carcinoma of the colon or rectum.
DB00642PemetrexedA folate analog used to treat mesothelioma and non-small cell lung cancer.
DB01030TopotecanAn antineoplastic agent used to treat ovarian cancer, small cell lung cancer, or cervical cancer.
DB00361VinorelbineA vinca alkaloid used in the treatment of metastatic non-small cell lung carcinoma (NSLC) and in conjunction with other drugs in locally advanced NSCLC.
DrugDrug NameTargetType
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor III-Btarget
DB00112BevacizumabComplement C1r subcomponenttarget
DB00112BevacizumabComplement C1q subcomponent subunit Atarget
DB00112BevacizumabComplement C1q subcomponent subunit Btarget
DB00112BevacizumabComplement C1q subcomponent subunit Ctarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor III-Atarget
DB00112BevacizumabHigh affinity immunoglobulin gamma Fc receptor Itarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-atarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-btarget
DB00112BevacizumabLow affinity immunoglobulin gamma Fc region receptor II-ctarget
DB00112BevacizumabVascular endothelial growth factor Atarget
DB00762IrinotecanDNA topoisomerase I, mitochondrialtarget
DB00762IrinotecanDNA topoisomerase 1target
DB00762IrinotecanCytochrome P450 3A4enzyme
DB00762IrinotecanCytochrome P450 3A5enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-1enzyme
DB00762IrinotecanUDP-glucuronosyltransferase 1-9enzyme
DB00762IrinotecanLiver carboxylesterase 1enzyme
DB00762IrinotecanCytochrome P450 3A7enzyme
DB00762IrinotecanCytochrome P450 2B6enzyme
DB00762IrinotecanSolute carrier family 22 member 3transporter
DB00762IrinotecanSolute carrier organic anion transporter family member 1B1transporter
DB00762IrinotecanMultidrug resistance-associated protein 1transporter
DB00762IrinotecanATP-binding cassette sub-family G member 2transporter
DB00762IrinotecanSerum albumincarrier
DB00762IrinotecanCocaine esteraseenzyme
DB00762IrinotecanCholinesteraseenzyme
DB00762IrinotecanP-glycoprotein 1transporter
DB00762IrinotecanCanalicular multispecific organic anion transporter 1transporter
DB00642PemetrexedThymidylate synthasetarget
DB00642PemetrexedDihydrofolate reductasetarget
DB00642PemetrexedTrifunctional purine biosynthetic protein adenosine-3target
DB00642PemetrexedDeoxycytidine kinaseenzyme
DB00642PemetrexedBifunctional purine biosynthesis protein PURHtarget
DB00642PemetrexedEquilibrative nucleoside transporter 1enzyme
DB00642PemetrexedSolute carrier family 22 member 8transporter
DB01030TopotecanDNA topoisomerase I, mitochondrialtarget
DB01030TopotecanDNA topoisomerase 1target
DB01030TopotecanATP-binding cassette sub-family G member 2transporter
DB01030TopotecanP-glycoprotein 1transporter
DB01030TopotecanCytochrome P450 3A4enzyme
DB01030TopotecanDNAtarget
DB01030TopotecanMultidrug and toxin extrusion protein 1transporter
DB01030TopotecanMultidrug and toxin extrusion protein 2transporter
DB00361VinorelbineTubulin beta chaintarget
DB00361VinorelbineCytochrome P450 3A4enzyme
DB00361VinorelbineP-glycoprotein 1transporter
DB00361VinorelbineCytochrome P450 2D6enzyme
DrugDrug NamePhaseStatusCount
DB11714Durvalumab1Recruiting1
DB06215Ferumoxytol1Suspended1
DB00762Irinotecan1Suspended1
DB11771Tremelimumab1Recruiting1
DB07232Veliparib1Suspended1
DB11595Atezolizumab2Active Not Recruiting1
DB00112Bevacizumab2Active Not Recruiting1
DB14776Camrelizumab2Recruiting1
DB01259Lapatinib2Completed1
DB09035Nivolumab2Active Not Recruiting1
DB06589Pazopanib2Completed1
DB14765Rivoceranib2Recruiting1
DB01275Hydralazine3Unknown Status1