Candidiasis infection

Also known as: Candidiasis / Candidal infection NOS / Moniliasis monilia / Monilial infection / Thrush NOS / [X]Candidiasis, unspecified / Candida infection / Candida infections / Moniliasis NOS / Monilia NOS / Moniliasis / Candida NOS / Candidiasis of unspecified site / Candidiasis NOS

DrugDrug NameDrug Description
DB00196FluconazoleTriazole antifungal agent that is used to treat oropharyngeal candidiasis and cryptococcal meningitis in AIDS. [PubChem]
DB01026KetoconazoleBroad spectrum antifungal agent used for long periods at high doses, especially in immunosuppressed patients. It is a racemate consisting of equimolar amounts of (2R,4S)- and (2S,4R)-ketoconazole with the chiral centers on the acetal ring.
DB01141MicafunginMicafungin is an antifungal drug. It belongs to the antifungal class of compounds known as echinocandins and exerts its effect by inhibiting the synthesis of 1,3-beta-D-glucan, an integral component of the fungal cell wall.
DB01110MiconazoleAn imidazole antifungal agent that is used topically and by intravenous infusion. [PubChem]
DB01593ZincA metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with anemia, short stature, hypogonadism, impaired wound healing, and geophagia. It is identified by the symbol _Zn_ [L2098]. A newer study suggests implies that an imbalance of zinc is associated with the neuronal damage associated with traumatic brain injury, stroke, and seizures [A32465]. Understanding the mechanisms that control brain zinc homeostasis is, therefore, imperative to the development of preventive and treatment regimens for these and other neurological disorders [A32465]. In addition to the above, recent review articles have already demonstrated the important role of zinc in the pathophysiology and treatment of affective disorders, plus discussed the potential value of zinc as a marker of these diseases [L2097]. Most recently, research has shown that polymorphism of the common polymorphism in zinc transporter _SLC30A8/ZnT8_ may increase susceptibility to type 2 diabetes provided novel insights into the role of zinc in diabetes [A32416].
DrugDrug NameTargetType
DB00196FluconazoleCytochrome P450 3A4enzyme
DB00196FluconazoleCytochrome P450 2C9enzyme
DB00196FluconazoleCytochrome P450 2C19enzyme
DB00196FluconazoleCytochrome P450 3A5enzyme
DB00196FluconazoleCytochrome P450 3A7enzyme
DB00196FluconazoleMultidrug resistance protein 1transporter
DB00196FluconazoleLanosterol 14-alpha demethylasetarget
DB00196FluconazoleCytochrome P450 11B1, mitochondrialenzyme
DB00196FluconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleCytochrome P450 3A7enzyme
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleMultidrug resistance protein 1transporter
DB01026KetoconazoleSolute carrier organic anion transporter family member 1A2transporter
DB01026KetoconazoleCholesterol side-chain cleavage enzyme, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 26A1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylaseenzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026Ketoconazole17-hydroxylasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026Ketoconazole11-hydroxylasetarget
DB01026KetoconazoleCytochrome P450 19A1target
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB01141MicafunginArylsulfatase Aenzyme
DB01141MicafunginCatechol O-methyltransferaseenzyme
DB01141Micafungin1,3-beta-glucan synthase component FKS1target
DB01110MiconazoleCytochrome P450 2C9enzyme
DB01110MiconazoleCytochrome P450 2D6enzyme
DB01110MiconazoleCytochrome P450 3A4enzyme
DB01110MiconazoleMultidrug resistance protein 1transporter
DB01110MiconazoleLanosterol 14-alpha demethylasetarget
DB01110MiconazoleNitric oxide synthase, endothelialtarget
DB01110MiconazoleNitric oxide synthase, inducibletarget
DB01110MiconazoleCalcium-activated potassium channel subunit alpha-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-1target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-2target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-3target
DB01110MiconazoleCalcium-activated potassium channel subunit beta-4target
DB01110MiconazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 1target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 2target
DB01110MiconazoleSmall conductance calcium-activated potassium channel protein 3target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 2target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 6target
DB01110MiconazolePotassium voltage-gated channel subfamily H member 7target
DB01110MiconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01110MiconazoleCytochrome P450 19A1enzyme
DB01110MiconazoleCytochrome P450 1A2enzyme
DB01110MiconazoleCytochrome P450 2A6enzyme
DB01110MiconazoleCytochrome P450 2B6enzyme
DB01110MiconazoleCytochrome P450 2C19enzyme
DB01110MiconazoleCytochrome P450 2E1enzyme
DB01110MiconazoleNuclear receptor subfamily 1 group I member 2target
DB01593ZincB1 bradykinin receptortarget
DB01593ZincMethylated-DNA--protein-cysteine methyltransferasetarget
DB01593ZincFructose-bisphosphate aldolase Atarget
DB01593ZincElongation factor 1-alpha 1target
DB01593ZincAlpha-enolasetarget
DB01593ZincGlyceraldehyde-3-phosphate dehydrogenase, testis-specifictarget
DB01593ZincNucleoside diphosphate kinase Atarget
DB01593ZincProtein disulfide-isomerasetarget
DB01593ZincProtein disulfide-isomerase A3target
DB01593ZincPeroxiredoxin-1target
DB01593ZincPhosphoserine phosphatasetarget
DB01593ZincTriosephosphate isomerasetarget
DB01593ZincElongation factor Tu, mitochondrialtarget
DB01593ZincEstrogen receptor alphatarget
DB01593ZincInterleukin-3target
DB01593ZincMetallothionein-2target
DB01593ZincCopper chaperone for superoxide dismutasetarget
DB01593ZincHistone deacetylase 1target
DB01593ZincHistone deacetylase 4target
DB01593ZincDNA-3-methyladenine glycosylasetarget
DB01593ZincSemenogelin-1target
DB01593ZincSuperoxide dismutase [Cu-Zn]target
DB01593ZincHistone deacetylase 8target
DB01593ZincApoptosis regulatory protein Sivatarget
DB01593ZincGlycine receptor subunit alpha-1target
DB01593ZincE3 ubiquitin-protein ligase Mdm2target
DB01593ZincInsulintarget
DB01593ZincUtrophintarget
DB01593ZincAspartoacylasetarget
DB01593ZincProtein S100-A8target
DB01593ZincProtein S100-A9target
DB01593ZincMatrix metalloproteinase-9target
DB01593ZincTumor protein p73target
DB01593ZincProtein S100-A2target
DB01593ZincCellular tumor antigen p53target
DB01593ZincMetallothionein-3target
DB01593ZincProgrammed cell death protein 6target
DB01593ZincDAN domain family member 5target
DB01593ZincMetallothionein-1Atarget
DB01593ZincAlpha-1B-glycoproteintarget
DB01593ZincAlpha-2-macroglobulintarget
DB01593ZincAngiotensinogentarget
DB01593ZincAlpha-2-HS-glycoproteintarget
DB01593ZincSerum amyloid P-componenttarget
DB01593ZincApolipoprotein A-Itarget
DB01593ZincApolipoprotein A-IItarget
DB01593ZincApolipoprotein A-IVtarget
DB01593ZincApolipoprotein B receptortarget
DB01593ZincApolipoprotein Etarget
DB01593ZincApolipoprotein L1target
DB01593ZincComplement C1q subcomponent subunit Btarget
DB01593ZincComplement C1q subcomponent subunit Ctarget
DB01593ZincComplement C1r subcomponenttarget
DB01593ZincComplement C1s subcomponenttarget
DB01593ZincComplement C3target
DB01593ZincComplement C4-Btarget
DB01593ZincC4b-binding protein alpha chaintarget
DB01593ZincC4b-binding protein beta chaintarget
DB01593ZincComplement C5target
DB01593ZincLys-63-specific deubiquitinase BRCC36target
DB01593ZincComplement component C8 alpha chaintarget
DB01593ZincComplement component C8 beta chaintarget
DB01593ZincComplement component C8 gamma chaintarget
DB01593ZincComplement factor Btarget
DB01593ZincComplement factor Htarget
DB01593ZincComplement factor Itarget
DB01593ZincClusterintarget
DB01593ZincCeruloplasmintarget
DB01593ZincCarboxypeptidase N catalytic chaintarget
DB01593ZincCarboxypeptidase N subunit 2target
DB01593ZincDermcidintarget
DB01593ZincDesmoplakintarget
DB01593ZincCoagulation factor XIItarget
DB01593ZincCoagulation factor XIII B chaintarget
DB01593ZincProthrombintarget
DB01593ZincFicolin-3target
DB01593ZincFibrinogen alpha chaintarget
DB01593ZincFibronectintarget
DB01593ZincGelsolintarget
DB01593ZincHemoglobin subunit alphatarget
DB01593ZincHemoglobin subunit betatarget
DB01593ZincHaptoglobin-related proteintarget
DB01593ZincHornerintarget
DB01593ZincInsulin-like growth factor-binding protein complex acid labile subunittarget
DB01593ZincIg alpha-1 chain C regiontarget
DB01593ZincIg mu chain C regiontarget
DB01593ZincImmunoglobulin kappa variable 1-17target
DB01593ZincIg kappa chain V-III region GOLtarget
DB01593ZincImmunoglobulin lambda variable 3-21target
DB01593ZincInter-alpha-trypsin inhibitor heavy chain H1target
DB01593ZincInter-alpha-trypsin inhibitor heavy chain H2target
DB01593ZincInter-alpha-trypsin inhibitor heavy chain H3target
DB01593ZincInter-alpha-trypsin inhibitor heavy chain H4target
DB01593ZincImmunoglobulin J chaintarget
DB01593ZincJunction plakoglobintarget
DB01593ZincPlasma kallikreintarget
DB01593ZincKininogen-1target
DB01593ZincKeratin, type II cytoskeletal 1target
DB01593ZincKeratin, type I cytoskeletal 10target
DB01593ZincKeratin, type I cytoskeletal 14target
DB01593ZincKeratin, type I cytoskeletal 16target
DB01593ZincKeratin, type II cytoskeletal 2 epidermaltarget
DB01593ZincKeratin, type II cytoskeletal 5target
DB01593ZincKeratin, type II cytoskeletal 6Atarget
DB01593ZincKeratin, type I cytoskeletal 9target
DB01593ZincAlpha-1-acid glycoprotein 2target
DB01593ZincN-acetylmuramoyl-L-alanine amidasetarget
DB01593ZincSerum paraoxonase/arylesterase 1target
DB01593ZincPregnancy zone proteintarget
DB01593ZincProtein S100-A7target
DB01593ZincSelenoprotein Ptarget
DB01593ZincAlpha-1-antitrypsintarget
DB01593ZincAlpha-1-antichymotrypsintarget
DB01593ZincKallistatintarget
DB01593ZincCorticosteroid-binding globulintarget
DB01593ZincHeparin cofactor 2target
DB01593ZincSex hormone-binding globulintarget
DB01593ZincSerotransferrintarget
DB01593ZincTransthyretintarget
DB01593ZincVitronectintarget
DB01593ZincAmyloid-like protein 1target
DB01593ZincAmyloid-like protein 2target
DB01593ZincAmyloid beta A4 proteintarget
DB01593ZincPoly [ADP-ribose] polymerase 1target
DB01593ZincCarbonic anhydrase 1enzyme
DB01593ZincCarboxypeptidase Eenzyme
DB01593ZincAlcohol dehydrogenase 1Cenzyme
DB01593ZincInsulin-degrading enzymeenzyme
DB01593ZincSuperoxide dismutase [Cu-Zn]enzyme
DrugDrug NamePhaseStatusCount
DB00196Fluconazole1Completed2
DB01167Itraconazole1Completed1
DB00333Methadone1Completed1
DB00582Voriconazole1Completed1
DB00362Anidulafungin2Completed2
DB00520Caspofungin2Completed2
DB01130Prednicarbate2Completed1
DB00582Voriconazole2Completed1
DB00257Clotrimazole2 / 3Not Yet Recruiting1
DB00196Fluconazole2 / 3Not Yet Recruiting1
DB01141Micafungin2 / 3Not Yet Recruiting1
DB01110Miconazole2 / 3Not Yet Recruiting1
DB00857Terbinafine2 / 3Not Yet Recruiting1
DB00525Tolnaftate2 / 3Not Yet Recruiting1
DB11117Undecylenate2 / 3Not Yet Recruiting1
DB00681Amphotericin B3Completed1
DB00681Amphotericin B3Terminated1
DB00681Amphotericin B3Unknown Status1
DB00362Anidulafungin3Completed2
DB00520Caspofungin3Completed2
DB00520Caspofungin3Terminated1
DB01190Clindamycin3Unknown Status1
DB00257Clotrimazole3Completed1
DB00196Fluconazole3Completed5
DB01026Ketoconazole3Unknown Status1
DB01141Micafungin3Completed2
DB01141Micafungin3Terminated1
DB00759Tetracycline3Unknown Status1
DB00582Voriconazole3Completed1
DB00582Voriconazole3Terminated1
DB00681Amphotericin B4Completed1
DB00362Anidulafungin4Completed1
DB00520Caspofungin4Completed1
DB01190Clindamycin4Recruiting1
DB00257Clotrimazole4Recruiting1
DB00196Fluconazole4Completed3
DB00196Fluconazole4Withdrawn1
DB01141Micafungin4Terminated2
DB01141Micafungin4Withdrawn1
DB01110Miconazole4Recruiting1
DB00994Neomycin4Recruiting1
DB00857Terbinafine4Recruiting1
DB00582Voriconazole4Completed2
DB00362AnidulafunginNot AvailableCompleted1
DB00196FluconazoleNot AvailableCompleted3