Complicated Pyelonephritis

Also known as: Pyelonephritis / Pyelonephritis NOS / Pyelonephritis, unspecified

Drug	Drug Name	Drug Description
DB09060	Avibactam	A non-β-lactam β-lactamase inhibitor used in combination with ceftazidime for the treatment of complicated intra-abdominal infections, complicated urinary tract infections, and hospital or ventilator-acquired pneumonia.
DB09050	Ceftolozane	A cephalosporin antibiotic used to treat complicated intra-abdominal infections in combination with metronidazole, complicated urinary tract infections, and hospital-acquired pneumonia.

Drug	Drug Name	Target	Type
DB09060	Avibactam	Canalicular multispecific organic anion transporter 1	transporter
DB09060	Avibactam	Solute carrier family 22 member 8	transporter
DB09060	Avibactam	Beta-lactamase TEM	target
DB09060	Avibactam	Beta-lactamase CTX-M	target
DB09060	Avibactam	Beta-lactamase	target
DB09060	Avibactam	Beta-lactamase SHV-1	target
DB09060	Avibactam	Beta-lactamase SHV-2	target
DB09060	Avibactam	Beta-lactamase SHV-1	target
DB09060	Avibactam	Class D OXA-48 carbapenemase	target
DB09060	Avibactam	Carbapenem-hydrolyzing beta-lactamase KPC	target
DB09060	Avibactam	Beta-lactamase CTX-M-15	target
DB09060	Avibactam	Extended-spectrum beta-lactamase PER-1	target
DB09050	Ceftolozane	Penicillin-binding protein 1B	target
DB09050	Ceftolozane	Penicillin-binding protein 3	target
DB09050	Ceftolozane	Penicillin-binding protein	target
DB09050	Ceftolozane	Penicillin-binding protein 1C	target
DB09050	Ceftolozane	Penicillin-binding protein 2	target

Drug	Drug Name	Phase	Status	Count