Rheumatoid Arthritis Completed Phase 4 Trials for Methotrexate (DB00563)

Also known as: RA / Rheumatic Arthritis / Arthritis, Rheumatoid / Arthritis,Rheumatoid / Rheumatoid Arthritis (RA) / Rheumatoid Arthritis(RA) / Arthritis, Rheumatoid (RA) / Systemic rheumatoid arthritis / Arthritis rheumatoid / Rheumatoid arthritis, unspecified / R arthritis / Rh arthritis / Atrophic arthritis

IndicationStatusPhase
DBCOND0027961 (Rheumatoid Arthritis)Completed4
clinicaltrials.gov IdentifierTitlePurposeDrugs
NCT02748785MTX Discontinuation and Vaccine ResponseTreatment
NCT00565409Study Comparing Etanercept in Combination With Methotrexate in Subjects With Rheumatoid ArthritisTreatment
NCT00760669An Observational Study of Infliximab Injection in Ankylosing Spondylitis, Rheumatoid Arthritis, Psoriatic Arthritis and Psoriasis Participants
NCT00808509A Pilot Study of the Feasibility of Discontinuation of Adalimumab in Stable Rheumatoid Arthritis Patients in Clinical Remission
NCT00896168An Efficacy and Safety Study of Infliximab in Participants With Rheumatoid ArthritisTreatment
NCT02644499Comparison of Combination Disease Modifying Antirheumatic Drugs With Methotrexate Therapy in Early Rheumatoid ArthritisTreatment
NCT02433184Very Early Versus Delayed Etanercept in Patients With RATreatment
NCT03449758Effect of Sarilumab on Patient-reported Outcomes in Patients With Active Rheumatoid ArthritisTreatment
NCT02557100Study to Assess Changes in the Immune Profile in Adults With Early Rheumatoid ArthritisBasic Science
NCT02874092Ticagrelor in Methotrexate-Resistant Rheumatoid ArthritisTreatment
NCT02831855Methotrexate Withdrawal Study of Tofacitinib Modified Release Formulation in Subjects With Rheumatoid ArthritisTreatment
NCT01172639Effectiveness in Daily Practice of Different Treatment Strategies for Early Rheumatoid Arthritis.Treatment
NCT01500278Study to Assess the Short- and Long-term Efficacy of Certolizumab Pegol Plus Methotrexate Compared to Adalimumab Plus Methotrexate in Subjects With Moderate to Severe Rheumatoid Arthritis (RA) Inadequately Responding to MethotrexateTreatment
NCT01308255Infliximab as Induction Therapy in Early Rheumatoid Arthritis (IDEA)Treatment
NCT00396747A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging StudyTreatment
NCT00422227Study Comparing Etanercept With Usual DMARD Therapy in Subjects With Rheumatoid Arthritis in the Asia Pacific RegionTreatment
NCT00420927Study of the Optimal Protocol for Methotrexate and Adalimumab Combination Therapy in Early Rheumatoid ArthritisTreatment
NCT00764725Comparison of MTX+Anti-TNF to MTX+Conventional DMARDs in Patients With Early Rheumatoid Arthritis (RA) Who Failed MTX Alone (SWEFOT)Treatment
NCT00195494Study Comparing Etanercept and Methotrexate vs. Methotrexate Alone in Rheumatoid ArthritisTreatment
NCT00209859Methotrexate and Cyclosporine in Treatment of Early Rheumatoid ArthritisTreatment
NCT00213564Gene Expression Profiling in PBMCs as a Tool for Prediction of Infliximab Responsiveness in Rheumatoid Arthritis
NCT00688103Efficacy and Safety of Etanercept in Active RA Despite Methotrexate Therapy in JapanTreatment
NCT00576433A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a Single Anti-TNF Inhibitor.Treatment
NCT01399697A Study of RoActemra/Actemra (Tocilizumab) in Combination With Methotrexate Versus RoActemra/Actemra Monotherapy in Patients With Rheumatoid Arthritis and an Inadequate Response to MethotrexateTreatment
NCT00654368CAMEO: Canadian Methotrexate and Etanercept Outcome StudyTreatment
NCT00848354Open-Label Study Comparing Etanercept to Conventional Disease Modifying Antirheumatic Drug (DMARD) TherapyTreatment
NCT00462345A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Therapies.Treatment
NCT01382940A Study on The Safety of Administering Rituximab at A More Rapid Rate in Patients With Rheumatoid ArthritisTreatment
NCT00934648A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to MethotrexateTreatment
NCT01746680Efficacy and Safety Study of Tacrobell to Treat Rheumatoid ArthritisTreatment
NCT00504777A Study of MabThera (Rituximab) in Combination With Methotrexate in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to Anti-TNF Agents.Treatment
NCT00502853A Pilot Study of MabThera (Rituximab) Evaluated by MRI in Patients With Rheumatoid Arthritis.Treatment
NCT00424502A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis Who Have Had an Inadequate Response to a TNF-Blocker.Treatment
NCT01185288A Study to Determine the Effect of Methotrexate (MTX) Dose on Clinical Outcome and Ultrasonographic Signs in Subjects With Moderately to Severely Active Rheumatoid Arthritis (RA) Treated With Adalimumab (MUSICA)Treatment
NCT01163747A Study of the Effects of RoActemra/Actemra on Vaccination in Patients With Rheumatoid Arthritis on Background Methotrexate (VISARA)Treatment
NCT01162421A Canadian Study to Evaluate Early Use of Adalimumab After Methotrexate Failure in Early Rheumatoid ArthritisTreatment
NCT01120366Success of Tocilizumab in RA Patients With Remission Induction and Sustained Efficacy After DiscontinuationTreatment
NCT01000610A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response to MethotrexateTreatment
NCT01404429Study of Two Different Starting Doses of Methotrexate When Starting Treatment in Rheumatoid ArthritisTreatment
NCT00252668Study Evaluating the Combination of Etanercept and Methotrexate in Rheumatoid Arthritis SubjectsTreatment
NCT00259610Treatment of Early Aggressive Rheumatoid Arthritis (TEAR)Treatment
NCT00244556Study Comparing Enbrel (Etanercept) Plus Methotrexate Versus Enbrel Alone in Active Rheumatoid Arthritis Despite Current Methotrexate TherapyTreatment
NCT00695188Methotrexate Polyglutamate Levels as a Marker for the Clinical Outcome in the Treatment of Rheumatoid ArthritisTreatment