Lyme Disease

Also known as: Lyme disease / Lymes disease / Borrelia burgdorferi infection / Lyme borreliosis / Lyme's disease / Lyme disease, unspecified

DrugDrug NameDrug Description
DB00671CefiximeCefixime, an antibiotic, is a third-generation cephalosporin like ceftriaxone and cefotaxime. Cefixime is highly stable in the presence of beta-lactamase enzymes. As a result, many organisms resistant to penicillins and some cephalosporins due to the presence of beta-lactamases, may be susceptible to cefixime. The antibacterial effect of cefixime results from inhibition of mucopeptide synthesis in the bacterial cell wall.
DB01112CefuroximeBroad-spectrum cephalosporin antibiotic resistant to beta-lactamase. It has been proposed for infections with gram-negative and gram-positive organisms, gonorrhea, and haemophilus.
DB01211ClarithromycinClarithromycin, a semisynthetic macrolide antibiotic derived from erythromycin, inhibits bacterial protein synthesis by binding to the bacterial 50S ribosomal subunit. Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process. Clarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration.
DrugDrug NamePhaseStatusCount
DB01212Ceftriaxone2Completed1
DB00316Acetaminophen3Not Yet Recruiting1
DB01212Ceftriaxone3Completed2
DB00254Doxycycline3Completed2
DB00788Naproxen3Not Yet Recruiting1
DB01060Amoxicillin4Completed1
DB01211Clarithromycin4Completed1
DB00254Doxycycline4Completed2
DB01611Hydroxychloroquine4Completed1
DB00417Phenoxymethylpenicillin4Completed1