Acute Low Back Pain

DrugDrug NameDrug Description
DB00697TizanidineTizanidine is a short-acting drug for the management of spasticity. Tizanidine is an agonist at a2-adrenergic receptor sites and presumably reduces spasticity by increasing presynaptic inhibition of motor neurons. In animal models, tizanidine has no direct effect on skeletal muscle fibers or the neuromuscular junction, and no major effect on monosynaptic spinal reflexes. The effects of tizanidine are greatest on polysynaptic pathways. The overall effect of these actions is thought to reduce facilitation of spinal motor neurons.
DrugDrug NamePhaseStatusCount
DB08992Eperisone2Completed1
DB12150Pelubiprofen2Completed1
DB00316Acetaminophen3Completed1
DB12911Nicoboxil3Completed1
DB11324Nonivamide3Completed1
DB00193Tramadol3Completed1
DB00316Acetaminophen4Completed1
DB00924Cyclobenzaprine4Completed1
DB00788Naproxen4Completed1
DB00497Oxycodone4Completed1