Kidney Diseases

Also known as: Renal Disease / Renal Diseases / Kidney Disease / Nephropathies / Nephropathy / Nephropathy NOS / Pyoureter / Kidney disorder / Disorder kidney / Renal disorder NOS / Disorder renal / Renal disorder

DrugDrug NameDrug Description
DB00887BumetanideBumetanide is a sulfamyl diuretic.
DB00695FurosemideA benzoic-sulfonamide-furan. It is a diuretic with fast onset and short duration that is used for edema and chronic renal insufficiency.
DB00524MetolazoneA quinazoline-sulfonamide that is considered a thiazide-like diuretic which is long-acting so useful in chronic renal failure. It also tends to lower blood pressure and increase potassium loss.
DB00214TorasemideTorasemide is a high-ceiling loop diuretic.[A174463] Structurally, it is a pyridine-sulfnyl urea used as an antihypertensive agent.[A319] On the FDA records, torasemide was developed and first introduced by the company Teva Pharmaceuticals and FDA approved in 2002.[L5248] However, torasemide was first approved for clinical use by the FDA on 1993.[L5257]
DrugDrug NameTargetType
DB00887BumetanideSolute carrier family 12 member 1target
DB00887BumetanideCystic fibrosis transmembrane conductance regulatortarget
DB00887BumetanideSolute carrier family 12 member 2target
DB00887BumetanideSolute carrier family 12 member 4target
DB00887BumetanideSolute carrier family 12 member 5target
DB00887BumetanideSodium/bile acid cotransportertransporter
DB00887BumetanideSolute carrier family 22 member 6transporter
DB00887BumetanideSolute carrier family 22 member 8transporter
DB00887BumetanideSolute carrier family 22 member 11transporter
DB00887BumetanideSolute carrier family 22 member 7transporter
DB00887BumetanideSolute carrier organic anion transporter family member 1A2transporter
DB00887BumetanideProstaglandin G/H synthase 2enzyme
DB00695FurosemideSolute carrier family 12 member 1target
DB00695FurosemideSerum albumincarrier
DB00695FurosemideSolute carrier family 22 member 6transporter
DB00695FurosemideSolute carrier family 22 member 5transporter
DB00695FurosemideSolute carrier family 22 member 8transporter
DB00695FurosemideCanalicular multispecific organic anion transporter 1transporter
DB00695FurosemideSolute carrier organic anion transporter family member 2A1transporter
DB00695FurosemideSolute carrier family 22 member 11transporter
DB00695Furosemide6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00695FurosemideCarbonic anhydrase 2target
DB00695FurosemideUDP-glucuronosyltransferase 1-1enzyme
DB00695FurosemideThyroxine-binding globulincarrier
DB00524MetolazoneSolute carrier family 12 member 3target
DB00214TorasemideSolute carrier family 12 member 1target
DB00214TorasemideCytochrome P450 2C8enzyme
DB00214TorasemideCytochrome P450 2C9enzyme
DB00214TorasemideSolute carrier organic anion transporter family member 1B1transporter
DB00214TorasemideSolute carrier family 12 member 2target
DB00214TorasemideSerum albumincarrier
DrugDrug NamePhaseStatusCount
DB11595Atezolizumab1Terminated1
DB09061Cannabidiol1Withdrawn1
DB06590Ceftaroline fosamil1Completed1
DB00872Conivaptan1Completed1
DB00470Dronabinol1Withdrawn1
DB06262Droxidopa1Withdrawn1
DB05187Elafibranor1Recruiting1
DB05408Emricasan1Completed1
DB05094Enzalutamide1Completed1
DB08899Enzalutamide1Completed1
DB00876Eprosartan1Completed1
DB00999Hydrochlorothiazide1Completed1
DB01137Levofloxacin1Completed1
DB00678Losartan1Completed1
DB11792Mirodenafil1Completed1
DB12536N-acetylmannosamine1Completed1
DB00526Oxaliplatin1Completed1
DB00571Propranolol1Completed1
DB06371Siplizumab1Completed1
DB00877Sirolimus1Completed1
DB00398Sorafenib1Completed1
DB01268Sunitinib1Terminated1
DB12199TRV-1200271Completed1
DB05521Telaprevir1Completed1
DB06402Telavancin1Completed1
DB12056Trebananib1Completed1
DB06267Udenafil1Completed1
DB00495Zidovudine1Withdrawn1
DB00316Acetaminophen1 / 2Completed1
DB00787Acyclovir1 / 2Completed1
DB00087Alemtuzumab1 / 2Completed2
DB00257Clotrimazole1 / 2Completed1
DB00111Daclizumab1 / 2Completed1
DB01075Diphenhydramine1 / 2Completed1
DB09132Gadoteric acid1 / 2Terminated1
DB01004Ganciclovir1 / 2Completed1
DB00959Methylprednisolone1 / 2Completed1
DB00688Mycophenolate mofetil1 / 2Completed2
DB00646Nystatin1 / 2Completed1
DB00738Pentamidine1 / 2Completed1
DB00635Prednisone1 / 2Completed1
DB00877Sirolimus1 / 2Completed2
DB01015Sulfamethoxazole1 / 2Completed1
DB00864Tacrolimus1 / 2Completed3
DB00440Trimethoprim1 / 2Completed1
DB01610Valganciclovir1 / 2Completed1
DB01593Zinc1 / 2Completed1
DB06256rPSGL-Ig1 / 2Completed1
DB00087Alemtuzumab2Completed1
DB00126Ascorbic acid2Recruiting1
DB00169Cholecalciferol2Recruiting1
DB00115Cyanocobalamin2Recruiting1
DB00016Erythropoietin2Completed1
DB01590Everolimus2Unknown Status1
DB06215Ferumoxytol2Completed1
DB00158Folic Acid2Recruiting1
DB05059ILY1012Unknown Status1
DB09146Iron saccharate2Completed1
DB09570Ixazomib2Recruiting1
DB00465Ketorolac2Recruiting1
DB06792Lanthanum carbonate2Completed2
DB00722Lisinopril2Recruiting1
DB00678Losartan2Recruiting1
DB06481Manitimus2Terminated1
DB04835Maraviroc2Recruiting1
DB02701Nicotinamide2Recruiting1
DB00165Pyridoxine2Recruiting1
DB00140Riboflavin2Recruiting1
DB00360Sapropterin2Completed1
DB00020Sargramostim2Terminated1
DB09325Sodium fluoride2Recruiting1
DB00398Sorafenib2Completed1
DB00864Tacrolimus2Completed1
DB00864Tacrolimus2Unknown Status1
DB00152Thiamine2Recruiting1
DB12255Vadadustat2Completed2
DB00162Vitamin A2Recruiting1
DB00163Vitamin E2Recruiting1
DB04906Voclosporin2Completed1
DB11693Voclosporin2Completed1
DB01029Irbesartan2 / 3Completed1
DB00421Spironolactone2 / 3Completed1
DB06151Acetylcysteine3Completed1
DB01012Cinacalcet3Completed2
DB01012Cinacalcet3Terminated1
DB00012Darbepoetin alfa3Completed7
DB00012Darbepoetin alfa3Terminated1
DB00016Erythropoietin3Completed1
DB01039Fenofibrate3Completed1
DB00492Fosinopril3Completed1
DB09132Gadoteric acid3Terminated1
DB00722Lisinopril3Terminated1
DB00678Losartan3Completed1
DB00678Losartan3Terminated1
DB00959Methylprednisolone3Completed1
DB01024Mycophenolic acid3Completed1
DB04899Nesiritide3Completed1
DB00275Olmesartan3Completed2
DB11133Omega-3 fatty acids3Active Not Recruiting1
DB00910Paricalcitol3Completed1
DB00175Pravastatin3Completed1
DB00635Prednisone3Completed1
DB01098Rosuvastatin3Completed1
DB12048Savolitinib3Active Not Recruiting1
DB00658Sevelamer3Completed1
DB00877Sirolimus3Completed1
DB01390Sodium bicarbonate3Completed1
DB01268Sunitinib3Active Not Recruiting1
DB00864Tacrolimus3Active Not Recruiting1
DB00864Tacrolimus3Completed3
DB00177Valsartan3Withdrawn1
DB06151Acetylcysteine4Completed2
DB00087Alemtuzumab4Unknown Status1
DB09026Aliskiren4Completed1
DB09026Aliskiren4Terminated1
DB00437Allopurinol4Completed1
DB00770Alprostadil4Unknown Status1
DB09312Antilymphocyte immunoglobulin (horse)4Completed1
DB00098Antithymocyte immunoglobulin (rabbit)4Completed1
DB01197Captopril4Completed1
DB01012Cinacalcet4Completed2
DB00758Clopidogrel4Recruiting1
DB01285Corticotropin4Completed1
DB00111Daclizumab4Unknown Status1
DB00012Darbepoetin alfa4Completed5
DB01234Dexamethasone4Terminated1
DB00633Dexmedetomidine4Recruiting1
DB00153Ergocalciferol4Unknown Status1
DB00016Erythropoietin4Terminated1
DB01590Everolimus4Unknown Status1
DB01276Exenatide4Not Yet Recruiting1
DB00158Folic Acid4Recruiting1
DB13879Glecaprevir4Not Yet Recruiting1
DB06792Lanthanum carbonate4Terminated1
DB00678Losartan4Completed2
DB01226Mivacurium4Completed1
DB00688Mycophenolate mofetil4Completed1
DB13878Pibrentasvir4Not Yet Recruiting1
DB06209Prasugrel4Completed1
DB00635Prednisone4Completed1
DB00635Prednisone4Unknown Status1
DB06213Regadenoson4Completed1
DB00728Rocuronium4Completed1
DB00877Sirolimus4Completed2
DB00877Sirolimus4Unknown Status1
DB01390Sodium bicarbonate4Completed1
DB00864Tacrolimus4Completed2
DB00864Tacrolimus4Unknown Status2
DB00277Theophylline4Completed1
DB08816Ticagrelor4Completed1
DB08816Ticagrelor4Recruiting1
DB11094Vitamin D4Unknown Status1
DB00437AllopurinolNot AvailableActive Not Recruiting1
DB00009AlteplaseNot AvailableRecruiting1
DB00136CalcitriolNot AvailableCompleted1
DB09126Chorionic Gonadotropin (Human)Not AvailableActive Not Recruiting1
DB01285CorticotropinNot AvailableWithdrawn1
DB09547CorticotropinNot AvailableWithdrawn1
DB11624Epoetin deltaNot AvailableTerminated1
DB00153ErgocalciferolNot AvailableTerminated1
DB00016ErythropoietinNot AvailableCompleted1
DB00569FondaparinuxNot AvailableWithdrawn1
DB11728FondaparinuxNot AvailableWithdrawn1
DB01362IohexolNot AvailableCompleted1
DB06792Lanthanum carbonateNot AvailableCompleted2
DB00910ParicalcitolNot AvailableCompleted1
DB12485PimonidazoleNot AvailableActive Not Recruiting1
DB01032ProbenecidNot AvailableCompleted1
DB00015ReteplaseNot AvailableRecruiting1
DB00412RosiglitazoneNot AvailableUnknown Status1
DB00624TestosteroneNot AvailableCompleted1