Postherpetic Neuralgia

Also known as: Neuralgia,Postherpetic / Neuralgia, Postherpetic / Post-herpetic neuralgia / Post herpetic neuralgia / PHN

DrugDrug NameDrug Description
DB00575ClonidineAn alpha-2 adrenergic agonist used to treat hypertension and severe cancer pain, among other conditions, and to treat withdrawal symptoms from various substances. It is also used to aid in the diagnosis of pheochromocytoma and to prevent migraines.
DB01151DesipramineA tricyclic antidepressant used in the treatment of depression.
DB00996GabapentinAn anticonvulsant medication used in the management of peripheral neuropathic pains, postherpetic neuralgia, and partial-onset seizures.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB09543Methyl salicylateA topical counter-irritant used for the symptomatic relief of acute musculoskeletal pain in the muscles, joints, and tendons.
DB00230PregabalinAn anticonvulsant drug used to treat neuropathic pain conditions and fibromyalgia, and for the treatment of partial onset seizures in combination with other anticonvulsants.
DrugDrug NameTargetType
DB00575ClonidineAlpha-2A adrenergic receptortarget
DB00575ClonidineCytochrome P450 2D6enzyme
DB00575ClonidineAlpha-2B adrenergic receptortarget
DB00575ClonidineAlpha-2C adrenergic receptortarget
DB00575ClonidineSolute carrier family 22 member 3transporter
DB00575ClonidineSolute carrier family 22 member 5transporter
DB00575ClonidineSolute carrier family 22 member 4transporter
DB00575ClonidineP-glycoprotein 1transporter
DB00575ClonidineCytochrome P450 1A2enzyme
DB00575ClonidineCytochrome P450 3A4enzyme
DB00575ClonidineCytochrome P450 1A1enzyme
DB00575ClonidineCytochrome P450 3A5enzyme
DB00575ClonidineAlpha-1A adrenergic receptortarget
DB00575ClonidineAlpha-1B adrenergic receptortarget
DB00575ClonidineAlpha-1D adrenergic receptortarget
DB00575ClonidineSerum albumincarrier
DB01151DesipramineMuscarinic acetylcholine receptor M1target
DB01151DesipramineSodium-dependent noradrenaline transportertarget
DB01151DesipramineBeta-2 adrenergic receptortarget
DB01151DesipramineMuscarinic acetylcholine receptor M2target
DB01151DesipramineSodium-dependent serotonin transportertarget
DB01151DesipramineHistamine H1 receptortarget
DB01151DesipramineBeta-1 adrenergic receptortarget
DB01151DesipramineCytochrome P450 2D6enzyme
DB01151DesipramineMuscarinic acetylcholine receptor M3target
DB01151DesipramineMuscarinic acetylcholine receptor M4target
DB01151DesipramineMuscarinic acetylcholine receptor M5target
DB01151DesipramineAlpha-1 adrenergic receptorstarget
DB01151Desipramine5-hydroxytryptamine receptor 2Atarget
DB01151DesipramineAlpha-1-acid glycoprotein 1carrier
DB01151DesipramineCytochrome P450 2B6enzyme
DB01151DesipramineCytochrome P450 3A4enzyme
DB01151DesipramineSolute carrier family 22 member 2transporter
DB01151DesipramineSolute carrier family 22 member 1transporter
DB01151DesipramineSolute carrier family 22 member 3transporter
DB01151DesipramineSolute carrier family 22 member 5transporter
DB01151DesipramineP-glycoprotein 1transporter
DB01151DesipramineSolute carrier family 22 member 4transporter
DB01151DesipramineCytochrome P450 1A2enzyme
DB01151DesipramineCytochrome P450 2E1enzyme
DB01151DesipramineSphingomyelin phosphodiesterasetarget
DB01151Desipramine5-hydroxytryptamine receptor 1Atarget
DB01151Desipramine5-hydroxytryptamine receptor 2Ctarget
DB01151DesipramineDopamine D2 receptortarget
DB01151DesipramineAlpha-2 adrenergic receptorstarget
DB00996GabapentinAdenosine receptor A1target
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00996GabapentinVoltage-dependent calcium channel subunit alpha-2/delta-2target
DB00996GabapentinBranched-chain-amino-acid aminotransferase, cytosolicenzyme
DB00996GabapentinLarge neutral amino acids transporter small subunit 1transporter
DB00996GabapentinVoltage-dependent N-type calcium channeltarget
DB00996GabapentinPotassium voltage-gated channel subfamily KQT member 3target
DB00996GabapentinPotassium voltage-gated channel subfamily KQT member 5target
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB00230PregabalinExcitatory amino acid transporter 3transporter
DB00230PregabalinVoltage-dependent calcium channel subunit alpha-2/delta-1target
DB00230PregabalinLarge neutral amino acids transporter small subunit 1transporter
DrugDrug NamePhaseStatusCount
DB00945Acetylsalicylic acid1Completed1
DB00281Lidocaine1Completed1
DB00230Pregabalin1Completed1
DB06774Capsaicin1 / 2Completed1
DB00742Mannitol1 / 2Completed1
DB00083Botulinum toxin type A2Completed1
DB05541Brivaracetam2Completed1
DB00297Bupivacaine2Completed1
DB06774Capsaicin2Completed2
DB12338Carisbamate2Completed1
DB09119Eslicarbazepine acetate2Completed1
DB01628Etoricoxib2Terminated1
DB04953Ezogabine2Completed1
DB12102Fulranumab2Terminated1
DB11769Funapide2Completed1
DB04922Gabapentin enacarbil2Completed2
DB08872Gabapentin enacarbil2Completed2
DB05214KD70402Completed1
DB06218Lacosamide2Completed2
DB01202Levetiracetam2Completed1
DB00281Lidocaine2Completed3
DB00281Lidocaine2Recruiting1
DB12563MK-06862Terminated1
DB11736PF-004897912Completed1
DB11722PH-7978042Completed1
DB00230Pregabalin2Completed2
DB00230Pregabalin2Terminated2
DB00750Prilocaine2Completed1
DB12626Senrebotase2Completed1
DB12626Senrebotase2Terminated1
DB09153Sodium chloride2Recruiting1
DB11998Sorivudine2Unknown Status1
DB12335Tanezumab2Completed1
DB06204Tapentadol2Completed1
DB09085Tetracaine2Completed1
DB00577Valaciclovir2Unknown Status1
DB09120Zucapsaicin2Completed1
DB09120Zucapsaicin2Terminated1
DB00555Lamotrigine2 / 3Terminated1
DB00813Fentanyl3Completed1
DB00996Gabapentin3Completed2
DB00230Pregabalin3Completed2
DB00230Pregabalin3Recruiting1
DB00899Remifentanil3Unknown Status1
DB00577Valaciclovir3Terminated1
DB00083Botulinum toxin type A4Completed2
DB06774Capsaicin4Completed1
DB01234Dexamethasone4Recruiting1
DB00476Duloxetine4Withdrawn1
DB01628Etoricoxib4Unknown Status1
DB00996Gabapentin4Completed2
DB00281Lidocaine4Completed2
DB00776Oxcarbazepine4Completed1
DB00230Pregabalin4Terminated1
DB00230Pregabalin4Withdrawn1
DB00296Ropivacaine4Recruiting1
DB00193Tramadol4Withdrawn1
DB00586DiclofenacNot AvailableCompleted1
DB01002LevobupivacaineNot AvailableRecruiting1