Type 2 Diabetes Mellitus Completed Phase 3 Trials for Vildagliptin (DB04876)

Also known as: Diabetes Mellitus Non-insulin-dependent / Type-2 Diabetes Mellitus / Diabetes Mellitus Type 2 (T2DM) / Diabetes Mellitus Type-2 / Type 2 Diabetes (T2DM) / Diabetes, Type 2 / Diabetes Mellitus, Type 2 (T2DM) / Diabetes Mellitus´╝îType 2 / Diabetes Type II / Type-II Diabetes Mellitus / Diabetes Mellitus 2 Type / T2DM / Diabetes Mellitus Type II / Type II Diabetes / Diabetes Mellitus, Type 2 / Type 2 Diabetes Mellitus (T2DM) / Diabetes Type Two / Diabetes Mellitus - Type 2 / Diabetes, Type II / Non-Insulin-Dependent Diabetes Mellitus / Diabetes Mellitus. Type 2 / Diabetes Type 2 / Type 2 Diabetes Mellitus (T2D) / Type 2 Diabetes (T2D) / Type II; Diabetes / Type II Diabetes Mellitus / Diabetes Mellitus, Type II / NIDDM / Type-2 Diabetes / Type 2 Diabetes Mellitus(T2DM) / Type 2 Diabetes / Type 2-diabetes / Noninsulin Dependent Diabetes Mellitus, Type II / Diabetes Mellitus Type 2 / Type Two Diabetes Mellitus / T2DM (Type 2 Diabetes Mellitus) / Type-2-diabetes Mellitus / Diabetes mellitus -adult onset / Diabetes mellitus non insulin-dep / Maturity onset diabetes / Diabetes mellitus maturity onset

IndicationStatusPhase
DBCOND0029752 (Type 2 Diabetes Mellitus)Completed3
clinicaltrials.gov IdentifierTitlePurposeDrugs
NCT01000688Vildagliptin and Endothelium-dependent VasodilatationPrevention
NCT01159249Long-term Safety Study of Vildagliptin in Patients With Type 2 DiabetesTreatment
NCT01822548Effect of Vildagliptin vs. Glibenclamide on Circulating Endothelial Progenitor Cell Number Type 2 DiabetesTreatment
NCT01242228A Study to Assess the Safety and Efficacy of ASP1941 in Combination With Dipeptidyl Peptidase-4 (DPP-4) Inhibitor in Type 2 Diabetic PatientsTreatment
NCT01224366Efficacy and Safety of Vildagliptin as add-on Therapy to Insulin in Patients With Type 2 Diabetes MellitusTreatment
NCT01233622Safety and Efficacy of Galvus as add-on Therapy to Metformin Plus GlimepirideTreatment
NCT00230464Acute Metabolic Effects of LAF 237 in Type 2 DiabeticsTreatment
NCT00822211Efficacy of add-on Therapy With Vildagliptin in Chinese Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin MonotherapyTreatment
NCT01257451Safety and Efficacy of Galvus in Elderly Type 2 Diabetes PatientsTreatment
NCT01357252Vildagliptin add-on to Glimepiride Versus Placebo Added to Glimepiride in Type 2 DiabetesTreatment
NCT01582230Efficacy and Safety of Vildagliptin 50mg Bid as an add-on Therapy to Insulin With or Without Metformin, in Patients With Type 2 Diabetes MellitusTreatment
NCT02343926Phase 3 Study to Compare the Efficacy and Safety of Gemigliptin and Vildagliptin as Add-on Therapy to Metformin in People With Type 2 Diabetes Inadequately Controlled With MetforminTreatment
NCT01871558Vildagliptin/Metformin in T2DM Patients Starting Basal InsulinTreatment
NCT00368134To Compare the Efficacy and Safey of Vildagliptin Compared to Voglibose in Patients With Type 2 DiabetesTreatment
NCT00383578Efficacy and Safety of Vildagliptin Compared to Metformin in Elderly Drug Naive Patients With Type 2 DiabetesTreatment
NCT00351832A Study To Compare the Effect of Vildagliptin Compared to Placebo in Patients With Type 2 DiabetesTreatment
NCT00351546A Study to Assess the Effects of DPP-4 Inhibition on Insulin Sensitivity in Type 2 DiabetesTreatment
NCT00351507A Study to Assess the Effects of Vildagliptin on Gastric Emptying in Patients With Type 2 DiabetesTreatment
NCT00351585A Study to Evaluate the Effect of Vildagliptin on the Maximum Insulin Secretion in Patients With Type 2 DiabetesTreatment
NCT00390520Efficacy and Safety of Vildagliptin Versus Placebo in Patients With Type 2 DiabetesTreatment
NCT00396071Efficacy and Safety of Vildagliptin Compared to Placebo on the Incretin Effect in Patients With Type 2 Diabetes Treated With MetforminTreatment
NCT00396357Efficacy/Safety of Vildagliptin and Metformin Combination Therapy in Patients With Type 2 Diabetes Not Well Controlled With Metformin AloneTreatment
NCT00396227Safety and Efficacy of Vildagliptin vs. Thiazolidinedione as add-on Therapy to Metformin in Patients With Type 2 Diabetes Not Controlled With Metformin AloneTreatment
NCT00389415Long Term Safety of Vildagliptin (100mg qd) In Patients With Type 2 DiabetesTreatment
NCT00765830Safety and Tolerability of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes and Moderate or Severe Renal Insufficiency (28 Week Extension)Treatment
NCT00728351Efficacy and Safety of Fixed Combination Therapy of Vildagliptin and Metformin (25/1000 mg Bid) in Patients With Type 2 Diabetes Inadequately Controlled With Prior Metformin Monotherapy (HbA1c 7.0-9.5%)Treatment
NCT01497522Efficacy and Safety of Vildagliptin as add-on Therapy to Metformin in Patients With Type 2 DiabetesTreatment
NCT00494884Vildagliptin 100 mg Once Daily vs. Placebo as add-on Therapy in Patients With Type 2 Diabetes Inadequately Controlled With MetforminTreatment
NCT00380445Effect of Vildagliptin on Fat and Muscle Metabolism in Patients With Type 2 DiabetesTreatment
NCT00380380A Study to Assess the Acute Effects of Vildagliptin on Gastric Emptying in Patients With Type 2 Diabetes.Treatment
NCT00138554Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Pioglitazone in Patients With Type 2 DiabetesTreatment
NCT00138580Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Glimepiride in Patients With Type 2 DiabetesTreatment
NCT00138593Extension to a Study of the Efficacy and Safety of Vildagliptin in Patients With Type 2 Diabetes With Hemoglobin A1c (HbA1c) 9-11%Treatment
NCT00138541Extension to a Study to Assess the Efficacy and Safety of Three Doses of Vildagliptin in Patients With Type 2 DiabetesTreatment
NCT00138515Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 DiabetesTreatment
NCT03088670Efficacy and Safety of Gosogliptin as Monotherapy and in Combination With Metformin vs. Vildagliptin as Monotherapy and in Combination With Metformin in Drug-naive Type 2 Diabetic Patients.Treatment
NCT00382096Efficacy of Fixed Combination Therapy of Vildagliptin and Metformin Compared to the Individual Monotherapy Components in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00101803Efficacy and Safety of Vildagliptin in Combination With Pioglitazone in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00099918Efficacy and Safety of Vildagliptin Compared to Rosiglitazone in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00102466Vildagliptin Compared to Gliclazide in Combination With Metformin in Patients With Type 2 DiabetesTreatment
NCT00120536Efficacy and Safety of Three Doses of Vildagliptin in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00468039A Sub-study to LMF237A2302 to Assess the Effect of 24 Weeks Treatment With Initial Combination of Vildagliptin Plus MetforminTreatment
NCT00300287A 56-Week Extension to a Clinical Study to Assess the Efficacy and Safety of Vildagliptin Compared to Placebo in Drug Naive Patients With Type 2 Diabetes and Mild HyperglycemiaTreatment
NCT00099892Efficacy and Safety of Vildagliptin in Combination With Metformin in Patients With Type 2 DiabetesTreatment
NCT00616811Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal InsufficiencyTreatment
NCT00770081Safety and Tolerability of Vildagliptin Versus Sitagliptin in Patients With Type 2 Diabetes and Severe Renal Insufficiency (28-week Extension Study)Treatment
NCT00325117To Assess the Efficacy and Safety of Vildagliptin as Add-on Therapy to Sulfonylurea in Patients With Type 2 Diabetes Inadequately Controlled With Sulfonylurea MonotherapyTreatment
NCT00325429Long-Term Safety Study of Vildagliptin in Patients With Type 2 DiabetesTreatment
NCT00237237Vildagliptin Compared to Pioglitazone in Combination With Metformin in Patients With Type 2 DiabetesTreatment
NCT00260156A Clinical Study to Assess the Effect of Vildagliptin on Beta Cell Function in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00099944Efficacy and Safety of Vildagliptin in Combination With Glimepiride in Patients With Type 2 DiabetesTreatment
NCT00110240Efficacy and Safety of Vildagliptin Compared to Acarbose in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00101673Efficacy and Safety of Vildagliptin in Patients With Type 2 Diabetes With HbA1c 9-11%Treatment
NCT00101712Efficacy and Safety of Vildagliptin Compared to Placebo in Patients With Type 2 Diabetes and Mild HyperglycemiaTreatment
NCT00102388Efficacy and Safety of Vildagliptin Compared to Gliclazide in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00099853Efficacy and Safety of Vildagliptin in Combination With Pioglitazone in Patients With Type 2 DiabetesTreatment
NCT00099866Efficacy and Safety of Vildagliptin Compared to Metformin in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00099905A Clinical Study to Assess the Efficacy and Safety of Three Doses of Vildagliptin in Patients With Type 2 DiabetesTreatment
NCT00099931Efficacy and Safety of Vildagliptin in Combination With Insulin in Patients With Type 2 DiabetesTreatment
NCT00138567Extension to a Study on the Efficacy and Safety of Vildagliptin Compared to Metformin in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00138606Extension to a Study on the Efficacy and Safety of Vildagliptin in Combination With Insulin in Patients With Type 2 DiabetesTreatment
NCT00138619Extension to a Study on the Efficacy and Safety of Vildagliptin Compared to Rosiglitazone in Drug Naive Patients With Type 2 DiabetesTreatment
NCT00106340Vildagliptin Compared to Glimepiride in Combination With Metformin in Patients With Type 2 DiabetesTreatment
NCT00351884Efficacy of Vildagliptin 100 MG as Compared to Placebo as Add-on to Metformin in Patients With Type 2 DiabetesTreatment
NCT00646542Safety and Tolerability of Vildagliptin Versus Placebo in Patients With Type 2 Diabetes and Moderate or Severe Renal InsufficiencyTreatment
NCT00651105Effect of LAF237 on Glucagon Secretion in Patients With Type 2 Diabetes and in Healthy SubjectsTreatment
NCT01262586Vildagliptin Glycemic Profiles Assessment Using a Continuous Glucose Monitoring Device.Treatment