Cardiothoracic Surgery

Also known as: Cardiac operation / Operation on heart (procedure) / Cardiac Surgical Procedures / Cardiac operation NOS / Cardiothoracic surgery (qualifier value)

Drug	Drug Name	Drug Description
DB01118	Amiodarone	A class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation.

Drug	Drug Name	Target	Type
DB01118	Amiodarone	Beta adrenergic receptor	target
DB01118	Amiodarone	HERG human cardiac K+ channel	target
DB01118	Amiodarone	Cytochrome P450 2C8	enzyme
DB01118	Amiodarone	Cytochrome P450 2C9	enzyme
DB01118	Amiodarone	Cytochrome P450 2D6	enzyme
DB01118	Amiodarone	Voltage-dependent T-type calcium channel subunit alpha-1I	target
DB01118	Amiodarone	Voltage gated L-type calcium channel	target
DB01118	Amiodarone	Cytochrome P450 3A4	enzyme
DB01118	Amiodarone	Cytochrome P450 1A2	enzyme
DB01118	Amiodarone	Cytochrome P450 1A1	enzyme
DB01118	Amiodarone	P-glycoprotein 1	transporter
DB01118	Amiodarone	Cytochrome P450 2C19	enzyme
DB01118	Amiodarone	Cytochrome P450 2A6	enzyme
DB01118	Amiodarone	Thyroid hormone receptor	target
DB01118	Amiodarone	Peroxisome proliferator-activated receptor gamma	target
DB01118	Amiodarone	Bile salt export pump	transporter
DB01118	Amiodarone	Solute carrier family 22 member 2	transporter
DB01118	Amiodarone	Cytochrome P450 2J2	enzyme
DB01118	Amiodarone	Peroxisome proliferator-activated receptor alpha	target
DB01118	Amiodarone	Peroxisome proliferator-activated receptor gamma coactivator 1-beta	target
DB01118	Amiodarone	Serum albumin	carrier

Drug	Drug Name	Phase	Status	Count
DB15314	Modimelanotide	2	Terminated	1
DB00126	Ascorbic acid	4	Unknown Status	1
DB01076	Atorvastatin	4	Unknown Status	1
DB00297	Bupivacaine	4	Unknown Status	1
DB00668	Epinephrine	4	Unknown Status	1
DB04899	Nesiritide	4	Terminated	1