Failed Prior Chemotherapy

Drug	Drug Name	Drug Description
DB00958	Carboplatin	A alkylating agent used to treat advanced ovarian cancer.
DB16732	Tisotumab vedotin	A tissue factor-directed antibody drug conjugate that is used to treat adults with recurrent or metastatic cervical cancer with disease progression on or after chemotherapy.

Drug	Drug Name	Target	Type
DB00958	Carboplatin	DNA	target
DB00958	Carboplatin	High affinity copper uptake protein 1	transporter
DB00958	Carboplatin	Probable low affinity copper uptake protein 2	transporter
DB00958	Carboplatin	Xanthine dehydrogenase/oxidase	enzyme
DB00958	Carboplatin	Myeloperoxidase	enzyme
DB00958	Carboplatin	Glutathione S-transferase theta-1	enzyme
DB00958	Carboplatin	Metallothionein-1A	enzyme
DB00958	Carboplatin	Metallothionein-2	enzyme
DB00958	Carboplatin	Superoxide dismutase [Cu-Zn]	enzyme
DB00958	Carboplatin	Glutathione S-transferase P	enzyme
DB00958	Carboplatin	Glutathione S-transferase Mu 1	enzyme
DB00958	Carboplatin	NAD(P)H dehydrogenase [quinone] 1	enzyme
DB00958	Carboplatin	Copper-transporting ATPase 1	transporter
DB00958	Carboplatin	Copper-transporting ATPase 2	transporter
DB00958	Carboplatin	ATP-binding cassette sub-family G member 2	transporter
DB00958	Carboplatin	Canalicular multispecific organic anion transporter 1	transporter
DB16732	Tisotumab vedotin	Cytochrome P450 3A4	enzyme
DB16732	Tisotumab vedotin	Tissue factor	target
DB16732	Tisotumab vedotin	P-glycoprotein 1	transporter

Drug	Drug Name	Phase	Status	Count
DB00530	Erlotinib	2	Completed	1