Schizophrenic Disorders

Also known as: Schizophrenic Disorder / Schizophrenia / Dementia Praecox / Schizophrenia NOS / Schizophrenia, unspecified / Unspecified schizophrenia / Unspecified schizophrenia, unspecified state

DrugDrug NameDrug Description
DB00321AmitriptylineAmitriptyline hydrochloride is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, amitriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, amitriptyline exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Tertiary amine TCAs, such as amitriptyline, are more potent inhibitors of serotonin reuptake than secondary amine TCAs, such as nortriptyline. TCAs also down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Amitriptyline may be used to treat depression, chronic pain (unlabeled use), irritable bowel syndrome (unlabeled use), diabetic neuropathy (unlabeled use), post-traumatic stress disorder (unlabeled use), and for migraine prophylaxis (unlabeled use).
DB01238AripiprazoleAripiprazole is an atypical antipsychotic medication used for the treatment of schizophrenia. It has also recently received FDA approval for the treatment of acute manic and mixed episodes associated with bipolar disorder. Aripiprazole appears to mediate its antipsychotic effects primarily by partial agonism at the D2 receptor. In addition to partial agonist activity at the D2 receptor, aripiprazole is also a partial agonist at the 5-HT1A receptor, and like the other atypical antipsychotics, aripiprazole displays an antagonist profile at the 5-HT2A receptor. Aripiprazole has moderate affinity for histamine and alpha adrenergic receptors, and no appreciable affinity for cholinergic muscarinic receptors.
DB06216AsenapineDeveloped by Schering-Plough after its merger with Organon International, asenapine is a sublingually administered, atypical antipsychotic for treatment of schizophrenia and acute mania associated with bipolar disorder. Asenapine also belongs to the dibenzo-oxepino pyrrole class. It is also for severe post-traumatic stress disorder nightmares in soldiers as an off-label use. FDA approved on August 13, 2009.
DB09128BrexpiprazoleBrexpiprazole is a novel D2 dopamine and serotonin 1A partial agonist, called serotonin-dopamine activity modulator (SDAM), and a potent antagonist of serotonin 2A receptors, noradrenergic alpha 1B and 2C receptors. Brexpiprazole is approved for the treatment of schizophrenia, and as an adjunctive treatment for major depressive disorder (MDD). Although it failed Phase II clinical trials for ADHD, it has been designed to provide improved efficacy and tolerability (e.g., less akathisia, restlessness and/or insomnia) over established adjunctive treatments for major depressive disorder (MDD).
DB06016CariprazineCariprazine is an antipsychotic drug developed by Gedeon Richter and marketed by Actavis under the trade name Vraylar. Cariprazine acts as a D2 and D3 receptor partial agonist, with high selectivity towards the D3 receptor. This mechanism is relatively unique, since many other antipsychotics are D2 and 5-HT2A agonists. Cariprazine was approved by the FDA in September 2015 and is indicated in the treatment of schizophrenia and bipolar disorder. Action on the dopaminergic systems makes it also potentially useful as an add-on therapy in major depressive disorder.
DB00477ChlorpromazineThe prototypical phenothiazine antipsychotic drug. Like the other drugs in this class, chlorpromazine's antipsychotic actions are thought to be due to long-term adaptation by the brain to blocking dopamine receptors. Chlorpromazine has several other actions and therapeutic uses, including as an antiemetic and in the treatment of intractable hiccup. [PubChem]
DB00363ClozapineA tricyclic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity. Agranulocytosis is a major adverse effect associated with administration of this agent. [PubChem]
DB00875FlupentixolFlupentixol is an antipsychotic neuroleptic drug. It is a thioxanthene, and therefore closely related to the phenothiazines. Its primary use is as a long acting injection given two or three weekly to people with schizophrenia who have a poor compliance with medication and suffer frequent relapses of illness. It is a D1 and D2 receptor antagonist. It is not approved in the United States.
DB00502HaloperidolA phenyl-piperidinyl-butyrophenone that is used primarily to treat schizophrenia and other psychoses. It is also used in schizoaffective disorder, delusional disorders, ballism, and tourette syndrome (a drug of choice) and occasionally as adjunctive therapy in mental retardation and the chorea of huntington disease. It is a potent antiemetic and is used in the treatment of intractable hiccups. (From AMA Drug Evaluations Annual, 1994, p279)
DB04946IloperidoneIloperidone is an atypical antipsychotic for the treatment of schizophrenia symptoms. Hoechst Marion Roussel Inc. made initial inquiries into the drug; however, in May 1996, they discontinued research, and in June 1997 gave research rights to Titan Pharmaceuticals. Titan then handed over worldwide development, manufacturing and marketing rights to Novartis in August 1998. On June 9, 2004, Titan Pharmaceuticals announced that the Phase III development rights have been acquired by Vanda Pharmaceuticals. FDA approved on May 9, 2009.
DB00408LoxapineAn antipsychotic agent used in schizophrenia. [PubChem]
DB08815LurasidoneLurasidone is an atypical antipsychotic developed by Dainippon Sumitomo Pharma. It was approved by the U.S. Food and Drug Administration (FDA) for treatment of schizophrenia on October 29, 2010 and is currently pending approval for the treatment of bipolar disorder in the United States. (Wikipedia)
DB01403MethotrimeprazineA phenothiazine with pharmacological activity similar to that of both chlorpromazine and promethazine. It has the histamine-antagonist properties of the antihistamines together with central nervous system effects resembling those of chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p604)
DB01618MolindoneAn indole derivative effective in schizophrenia and other psychoses and possibly useful in the treatment of the aggressive type of undersocialized conduct disorder. Molindone has much lower affinity for D2 receptors than most antipsychotic agents and has a relatively low affinity for D1 receptors. It has only low to moderate affinity for cholinergic and alpha-adrenergic receptors. Some electrophysiologic data from animals indicate that molindone has certain characteristics that resemble those of clozapine. (From AMA Drug Evaluations Annual, 1994, p283)
DB00540NortriptylineNortriptyline hydrochloride, the N-demethylated active metabolite of amitriptyline, is a dibenzocycloheptene-derivative tricyclic antidepressant (TCA). TCAs are structurally similar to phenothiazines. They contain a tricyclic ring system with an alkyl amine substituent on the central ring. In non-depressed individuals, nortriptyline does not affect mood or arousal, but may cause sedation. In depressed individuals, nortriptyline exerts a positive effect on mood. TCAs are potent inhibitors of serotonin and norepinephrine reuptake. Secondary amine TCAs, such as nortriptyline, are more potent inhibitors of norepinephrine reuptake than tertiary amine TCAs, such as amitriptyline. TCAs also down-regulate cerebral cortical β-adrenergic receptors and sensitize post-synaptic serotonergic receptors with chronic use. The antidepressant effects of TCAs are thought to be due to an overall increase in serotonergic neurotransmission. TCAs also block histamine-H1 receptors, α1-adrenergic receptors and muscarinic receptors, which accounts for their sedative, hypotensive and anticholinergic effects (e.g. blurred vision, dry mouth, constipation, urinary retention), respectively. See toxicity section below for a complete listing of side effects. Nortriptyline exerts less anticholinergic and sedative side effects compared to the tertiary amine TCAs, amitriptyline and clomipramine. Nortriptyline may be used to treat depression, chronic pain (unlabeled use), irritable bowel syndrome (unlabeled use), diabetic neuropathy (unlabeled use), post-traumatic stress disorder (unlabeled use), and for migraine prophylaxis (unlabeled use).
DB00334OlanzapineOlanzapine is an atypical antipsychotic, approved by the FDA in 1996. Olanzapine is manufactured and marketed by the pharmaceutical company Eli Lilly and Company, whose patent for olanzapine proper ends in 2011.
DB01267PaliperidonePaliperidone is the primary active metabolite of the older antipsychotic risperidone. While its specific mechanism of action is unknown, it is believed that paliperidone and risperidone act via similar if not the same pathways. It has been proposed that the drug's therapeutic activity in schizophrenia is mediated through a combination of central dopamine Type 2 (D2) and serotonin Type 2 (5HT2A) receptor antagonism. Paliperidone is also active as an antagonist at alpha 1 and alpha 2 adrenergic receptors and H1 histaminergic receptors, which may explain some of the other effects of the drug. Paliperidone was approved by the FDA for treatment of schizophrenia on December 20, 2006.
DB00850PerphenazineAn antipsychotic phenothiazine derivative with actions and uses similar to those of chlorpromazine. [PubChem]
DB01621PipotiazinePipotiazine has actions similar to those of other phenothiazines. Among the different phenothiazine derivatives, it appears to be less sedating and to have a weak propensity for causing hypotension or potentiating the effects of CNS depressants and anesthetics. However, it produces a high incidence of extra pyramidal reactions. It is used for the maintenance treatment of chronic non-agitated schizophrenic patients. Symptoms of overdose include severe extrapyramidal manifestations, hypotension, lethargy and sedation.
DB00433ProchlorperazineA phenothiazine antipsychotic used principally in the treatment of nausea; vomiting; and vertigo. It is more likely than chlorpromazine to cause extrapyramidal disorders. (From Martindale, The Extra Pharmacopoeia, 30th ed, p612)
DB01224QuetiapineQuetiapine is indicated for the treatment of schizophrenia as well as for the treatment of acute manic episodes associated with bipolar I disorder. The antipsychotic effect of quetiapine is thought by some to be mediated through antagonist activity at dopamine and serotonin receptors. Specifically the D1 and D2 dopamine, the alpha 1 adrenoreceptor and alpha 2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also has an antagonistic effect on the histamine H1 receptor.
DB00734RisperidoneRisperidone, a benzisoxazole derivative, is an atypical antipsychotic drug with high affinity for 5-hydrotryptamine (5-HT) and dopamine D2 receptors. It is used primarily in the management of schizophrenia, inappropriate behavior in severe dementia and manic episodes associated with bipolar I disorder. Risperidone is effective for treating the positive and negative symptoms of schizophrenia owing to its affinity for its “loose” binding affinity for dopamine D2 receptors and additional 5-HT antagonism compared to first generation antipsychotics, which are strong, non-specific dopamine D2 receptor antagonists.
DB01622ThioproperazineThioproperazine is a potent neuroleptic with antipsychotic properties. Thioproperazine has a marked cataleptic and antiapomorphine activity associated with relatively slight sedative, hypothermic and spasmolytic effects. It is virtually without antiserotonin and hypotensive action and has no antihistaminic property. It is used for the treatment of all types of acute and chronic schizophrenia, including those which did not respond to the usual neuroleptics; manic syndromes. Overdosage may result in severe extrapyramidal symptoms with dysphagia, marked sialorrhea, persistent and rapidly increasing hyperthermia, pulmonary syndrome, state of shock with pallor and profuse sweating, which may be followed by collapse and coma. LD50 in mice is 70 mg/kg I.V., 120 mg/kg I.P., 500 mg/kg S.C. and 830 mg/kg P.O.
DB00679ThioridazineA phenothiazine antipsychotic used in the management of psychoses, including schizophrenia, and in the control of severely disturbed or agitated behavior. It has little antiemetic activity. Thioridazine has a higher incidence of antimuscarinic effects, but a lower incidence of extrapyramidal symptoms, than chlorpromazine. (From Martindale, The Extra Pharmacopoeia, 30th ed, p618). Thioridazine was withdrawn worldwide in 2005 due to it's association with cardiac arrythmias.
DB01623ThiothixeneA thioxanthine used as an antipsychotic agent. Its effects are similar to the phenothiazine antipsychotics. [PubChem]
DB00831TrifluoperazineA phenothiazine with actions similar to chlorpromazine. It is used as an antipsychotic and an antiemetic. [PubChem]
DB00246ZiprasidoneZiprasidone (marketed as Geodon, Zeldox) was the fifth atypical antipsychotic to gain FDA approval (February 2001). Ziprasidone is Food and Drug Administration (FDA) approved for the treatment of schizophrenia, and the intramuscular injection form of ziprasidone is approved for acute agitation in schizophrenic patients. Ziprasidone has also received approval for acute treatment of mania associated with bipolar disorder. [Wikipedia]
DB01624ZuclopenthixolZuclopenthixol, also known as Zuclopentixol or Zuclopenthixolum, is an antipsychotic agent. Zuclopenthixol is a thioxanthene-based neuroleptic with therapeutic actions similar to the phenothiazine antipsychotics. It is an antagonist at D1 and D2 dopamine receptors. Major brands of zuclopenthixol are Cisordinol, Acuphase, and Clopixol. This drug is a liquid. This compound belongs to the thioxanthenes. These are organic polycyclic compounds containing a thioxanthene moiety, which is an aromatic tricycle derived from xanthene by replacing the oxygen atom with a sulfur atom. Known drug targets of zuclopenthixol include 5-hydroxytryptamine receptor 2A, D(1B) dopamine receptor, D(2) dopamine receptor, D(1A) dopamine receptor, and alpha-1A adrenergic receptor. It is known that zuclopenthixol is metabolized by Cytochrome P450 2D6. Zuclopenthixol was approved for use in Canada in 2011, but is not approved for use in the United States.
DrugDrug NameTargetType
DB00321AmitriptylineSodium-dependent serotonin transportertarget
DB00321AmitriptylineSodium-dependent noradrenaline transportertarget
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 2target
DB00321AmitriptylineAlpha-2A adrenergic receptortarget
DB00321AmitriptylineCytochrome P450 1A2enzyme
DB00321AmitriptylineCytochrome P450 2C19enzyme
DB00321AmitriptylineCytochrome P450 2D6enzyme
DB00321AmitriptylineSerum albumincarrier
DB00321AmitriptylineAlpha-1-acid glycoprotein 1carrier
DB00321AmitriptylineMuscarinic acetylcholine receptor M1target
DB00321AmitriptylineMuscarinic acetylcholine receptor M2target
DB00321AmitriptylineMuscarinic acetylcholine receptor M3target
DB00321AmitriptylineMuscarinic acetylcholine receptor M4target
DB00321AmitriptylineMuscarinic acetylcholine receptor M5target
DB00321AmitriptylineHistamine H1 receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 2Atarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Atarget
DB00321AmitriptylineAlpha-1A adrenergic receptortarget
DB00321AmitriptylineCytochrome P450 3A4enzyme
DB00321AmitriptylineCytochrome P450 3A5enzyme
DB00321AmitriptylinePotassium voltage-gated channel subfamily A member 1target
DB00321AmitriptylinePotassium voltage-gated channel subfamily D member 2target
DB00321AmitriptylinePotassium voltage-gated channel subfamily D member 3target
DB00321AmitriptylineAlpha-1D adrenergic receptortarget
DB00321AmitriptylineDelta-type opioid receptortarget
DB00321AmitriptylineKappa-type opioid receptortarget
DB00321AmitriptylineHigh affinity nerve growth factor receptortarget
DB00321AmitriptylineBDNF/NT-3 growth factors receptortarget
DB00321AmitriptylineCytochrome P450 2C9enzyme
DB00321AmitriptylineMultidrug resistance protein 1transporter
DB00321AmitriptylineCytochrome P450 2B6enzyme
DB00321AmitriptylineCytochrome P450 2C8enzyme
DB00321AmitriptylineCytochrome P450 2E1enzyme
DB00321AmitriptylineHistamine H2 receptortarget
DB00321AmitriptylineHistamine H4 receptortarget
DB00321AmitriptylineSigma non-opioid intracellular receptor 1target
DB00321Amitriptyline5-hydroxytryptamine receptor 2Ctarget
DB00321AmitriptylineAlpha-1B adrenergic receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 7target
DB00321Amitriptyline5-hydroxytryptamine receptor 1Dtarget
DB00321AmitriptylineMu-type opioid receptortarget
DB00321Amitriptyline5-hydroxytryptamine receptor 1Btarget
DB00321Amitriptyline5-hydroxytryptamine receptor 6target
DB00321AmitriptylinePotassium voltage-gated channel subfamily KQT member 3target
DB00321AmitriptylineBeta adrenergic receptortarget
DB01238AripiprazoleD(2) dopamine receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Atarget
DB01238AripiprazoleCytochrome P450 3A4enzyme
DB01238AripiprazoleCytochrome P450 2D6enzyme
DB01238Aripiprazole5-hydroxytryptamine receptor 1Btarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Dtarget
DB01238Aripiprazole5-hydroxytryptamine receptor 1Etarget
DB01238AripiprazoleD(1A) dopamine receptortarget
DB01238AripiprazoleD(1B) dopamine receptortarget
DB01238AripiprazoleD(3) dopamine receptortarget
DB01238AripiprazoleD(4) dopamine receptortarget
DB01238Aripiprazole5-hydroxytryptamine receptor 2Ctarget
DB01238Aripiprazole5-hydroxytryptamine receptor 3Atarget
DB01238Aripiprazole5-hydroxytryptamine receptor 6target
DB01238Aripiprazole5-hydroxytryptamine receptor 7target
DB01238AripiprazoleHistamine H1 receptortarget
DB01238AripiprazoleAlpha-1A adrenergic receptortarget
DB01238AripiprazoleAlpha-1B adrenergic receptortarget
DB01238AripiprazoleAlpha-2A adrenergic receptortarget
DB01238AripiprazoleAlpha-2B adrenergic receptortarget
DB01238AripiprazoleAlpha-2C adrenergic receptortarget
DB01238AripiprazoleMuscarinic acetylcholine receptor M1target
DB01238AripiprazoleMuscarinic acetylcholine receptor M2target
DB01238AripiprazoleMuscarinic acetylcholine receptor M3target
DB01238AripiprazoleMuscarinic acetylcholine receptor M4target
DB01238AripiprazoleMuscarinic acetylcholine receptor M5target
DB01238AripiprazoleCytochrome P450 3A5enzyme
DB01238AripiprazoleCytochrome P450 3A7enzyme
DB06216AsenapineCytochrome P450 1A2enzyme
DB06216AsenapineCytochrome P450 2D6enzyme
DB06216AsenapineUDP-glucuronosyltransferase 1-4enzyme
DB06216AsenapineCytochrome P450 3A4enzyme
DB06216Asenapine5-hydroxytryptamine receptor 1Atarget
DB06216Asenapine5-hydroxytryptamine receptor 1Btarget
DB06216Asenapine5-hydroxytryptamine receptor 2Atarget
DB06216Asenapine5-hydroxytryptamine receptor 2Btarget
DB06216Asenapine5-hydroxytryptamine receptor 2Ctarget
DB06216Asenapine5-hydroxytryptamine receptor 6target
DB06216Asenapine5-hydroxytryptamine receptor 7target
DB06216AsenapineAlpha-2A adrenergic receptortarget
DB06216AsenapineAlpha-2B adrenergic receptortarget
DB06216AsenapineAlpha-2C adrenergic receptortarget
DB06216AsenapineAlpha-1A adrenergic receptortarget
DB06216AsenapineD(1A) dopamine receptortarget
DB06216AsenapineD(2) dopamine receptortarget
DB06216AsenapineD(3) dopamine receptortarget
DB06216AsenapineD(4) dopamine receptortarget
DB06216AsenapineHistamine H1 receptortarget
DB06216AsenapineHistamine H2 receptortarget
DB06216Asenapine5-hydroxytryptamine receptor 5Atarget
DB06216AsenapineBeta-1 adrenergic receptortarget
DB06216AsenapineBeta-2 adrenergic receptortarget
DB09128BrexpiprazoleCytochrome P450 2D6enzyme
DB09128BrexpiprazoleCytochrome P450 3A4enzyme
DB09128Brexpiprazole5-hydroxytryptamine receptor 1Atarget
DB09128BrexpiprazoleD(2) dopamine receptortarget
DB09128Brexpiprazole5-hydroxytryptamine receptor 2Atarget
DB09128BrexpiprazoleAlpha-2C adrenergic receptortarget
DB09128BrexpiprazoleAlpha-1B adrenergic receptortarget
DB06016CariprazineD(3) dopamine receptortarget
DB06016CariprazineD(2) dopamine receptortarget
DB06016CariprazineCytochrome P450 3A4enzyme
DB06016CariprazineCytochrome P450 2D6enzyme
DB06016Cariprazine5-hydroxytryptamine receptor 1Atarget
DB06016Cariprazine5-hydroxytryptamine receptor 2Btarget
DB06016Cariprazine5-hydroxytryptamine receptor 2Atarget
DB06016CariprazineHistamine H1 receptortarget
DB00477ChlorpromazineD(2) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Atarget
DB00477ChlorpromazineCytochrome P450 2D6enzyme
DB00477ChlorpromazineCholinesteraseenzyme
DB00477ChlorpromazineCytochrome P450 1A2enzyme
DB00477ChlorpromazineSerum albumincarrier
DB00477ChlorpromazineSolute carrier family 22 member 1transporter
DB00477ChlorpromazineBile salt export pumptransporter
DB00477ChlorpromazineMultidrug resistance protein 1transporter
DB00477ChlorpromazineD(1A) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 1Atarget
DB00477ChlorpromazineAlpha-1A adrenergic receptortarget
DB00477ChlorpromazineAlpha-1B adrenergic receptortarget
DB00477ChlorpromazineCytochrome P450 2E1enzyme
DB00477ChlorpromazineCytochrome P450 3A4enzyme
DB00477ChlorpromazineHistamine H1 receptortarget
DB00477ChlorpromazinePotassium voltage-gated channel subfamily H member 2target
DB00477ChlorpromazineD(1) dopamine receptortarget
DB00477ChlorpromazineD(3) dopamine receptortarget
DB00477ChlorpromazineD(4) dopamine receptortarget
DB00477ChlorpromazineD(1B) dopamine receptortarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 2Ctarget
DB00477Chlorpromazine5-hydroxytryptamine 2 receptortarget
DB00477ChlorpromazineAlpha-1 adrenergic receptorstarget
DB00477ChlorpromazineAlpha-2 adrenergic receptorstarget
DB00477ChlorpromazineMuscarinic acetylcholine receptor M1target
DB00477ChlorpromazineMuscarinic acetylcholine receptor M3target
DB00477ChlorpromazineSphingomyelin phosphodiesterasetarget
DB00477ChlorpromazineCalmodulintarget
DB00477Chlorpromazinealpha1-acid glycoproteintarget
DB00477Chlorpromazine5-hydroxytryptamine receptor 6target
DB00477Chlorpromazine5-hydroxytryptamine receptor 7target
DB00477ChlorpromazineHistamine H4 receptortarget
DB00363ClozapineD(4) dopamine receptortarget
DB00363ClozapineHistamine H1 receptortarget
DB00363ClozapineD(2) dopamine receptortarget
DB00363ClozapineNeuron-specific vesicular protein calcyontarget
DB00363ClozapineHistamine H4 receptortarget
DB00363Clozapine5-hydroxytryptamine receptor 2Atarget
DB00363Clozapine5-hydroxytryptamine receptor 1Atarget
DB00363Clozapine5-hydroxytryptamine receptor 2Ctarget
DB00363ClozapineD(1A) dopamine receptortarget
DB00363ClozapineCytochrome P450 1A2enzyme
DB00363ClozapineCytochrome P450 2D6enzyme
DB00363ClozapineD(3) dopamine receptortarget
DB00363ClozapineMuscarinic acetylcholine receptor M1target
DB00363ClozapineMuscarinic acetylcholine receptor M2target
DB00363ClozapineMuscarinic acetylcholine receptor M3target
DB00363ClozapineMuscarinic acetylcholine receptor M4target
DB00363ClozapineMuscarinic acetylcholine receptor M5target
DB00363Clozapine5-hydroxytryptamine receptor 1Btarget
DB00363Clozapine5-hydroxytryptamine receptor 1Dtarget
DB00363Clozapine5-hydroxytryptamine receptor 1Etarget
DB00363Clozapine5-hydroxytryptamine receptor 3Atarget
DB00363Clozapine5-hydroxytryptamine receptor 6target
DB00363Clozapine5-hydroxytryptamine receptor 7target
DB00363ClozapineAlpha-1A adrenergic receptortarget
DB00363ClozapineAlpha-1B adrenergic receptortarget
DB00363ClozapineAlpha-2A adrenergic receptortarget
DB00363ClozapineAlpha-2B adrenergic receptortarget
DB00363ClozapineAlpha-2C adrenergic receptortarget
DB00363ClozapineCytochrome P450 2C9enzyme
DB00363ClozapineMultidrug resistance protein 1transporter
DB00363ClozapineCytochrome P450 3A4enzyme
DB00363ClozapineCytochrome P450 2C19enzyme
DB00363ClozapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00363ClozapineUDP-glucuronosyltransferase 1-4enzyme
DB00363ClozapineCytochrome P450 1A1enzyme
DB00363ClozapineCytochrome P450 1B1enzyme
DB00363ClozapineCytochrome P450 2A6enzyme
DB00363ClozapineCytochrome P450 2C8enzyme
DB00363ClozapineCytochrome P450 2E1enzyme
DB00363ClozapineGlutathione S-transferase Ptarget
DB00875FlupentixolAlpha-1A adrenergic receptortarget
DB00875FlupentixolD(2) dopamine receptortarget
DB00875FlupentixolD(1A) dopamine receptortarget
DB00875FlupentixolAromatic-L-amino-acid decarboxylaseenzyme
DB00875Flupentixol5-hydroxytryptamine receptor 2Atarget
DB00875FlupentixolMultidrug resistance protein 1transporter
DB00875FlupentixolMuscarinic acetylcholine receptor M1target
DB00502HaloperidolD(2) dopamine receptortarget
DB00502HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
DB00502HaloperidolD(1A) dopamine receptortarget
DB00502HaloperidolCytochrome P450 1A2enzyme
DB00502HaloperidolCytochrome P450 2D6enzyme
DB00502Haloperidol5-hydroxytryptamine receptor 2Atarget
DB00502HaloperidolD(3) dopamine receptortarget
DB00502HaloperidolCytochrome P450 3A4enzyme
DB00502HaloperidolCytochrome P450 3A5enzyme
DB00502HaloperidolCytochrome P450 3A7enzyme
DB00502HaloperidolMultidrug resistance protein 1transporter
DB00502HaloperidolCarbonyl reductase [NADPH] 1enzyme
DB00502HaloperidolUDP-glucuronosyltransferase 1-9enzyme
DB00502HaloperidolCytochrome P450 1A1enzyme
DB00502HaloperidolCytochrome P450 2C19enzyme
DB00502HaloperidolCytochrome P450 2C9enzyme
DB00502HaloperidolMelanin-concentrating hormone receptor 1target
DB00502HaloperidolSynaptic vesicular amine transportertarget
DB04946IloperidoneD(2) dopamine receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 2Atarget
DB04946IloperidoneCytochrome P450 2D6enzyme
DB04946IloperidoneCytochrome P450 3A4enzyme
DB04946IloperidoneCytochrome P450 3A5enzyme
DB04946IloperidoneCytochrome P450 3A7enzyme
DB04946IloperidoneCytochrome P450 2E1enzyme
DB04946IloperidoneD(3) dopamine receptortarget
DB04946IloperidoneAlpha-1A adrenergic receptortarget
DB04946IloperidoneD(4) dopamine receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 6target
DB04946Iloperidone5-hydroxytryptamine receptor 7target
DB04946IloperidoneHistamine H1 receptortarget
DB04946IloperidoneD(1A) dopamine receptortarget
DB04946Iloperidone5-hydroxytryptamine receptor 1Atarget
DB04946IloperidoneCytochrome P450 1A2enzyme
DB04946IloperidoneAlpha-2C adrenergic receptortarget
DB00408LoxapineD(1A) dopamine receptortarget
DB00408LoxapineD(2) dopamine receptortarget
DB00408Loxapine5-hydroxytryptamine receptor 2Atarget
DB00408Loxapine5-hydroxytryptamine receptor 2Ctarget
DB00408Loxapine5-hydroxytryptamine receptor 1Atarget
DB00408Loxapine5-hydroxytryptamine receptor 1Btarget
DB00408Loxapine5-hydroxytryptamine receptor 1Dtarget
DB00408Loxapine5-hydroxytryptamine receptor 1Etarget
DB00408Loxapine5-hydroxytryptamine receptor 3Atarget
DB00408Loxapine5-hydroxytryptamine receptor 5Atarget
DB00408Loxapine5-hydroxytryptamine receptor 6target
DB00408Loxapine5-hydroxytryptamine receptor 7target
DB00408LoxapineAlpha-1A adrenergic receptortarget
DB00408LoxapineAlpha-1B adrenergic receptortarget
DB00408LoxapineAlpha-2A adrenergic receptortarget
DB00408LoxapineAlpha-2B adrenergic receptortarget
DB00408LoxapineAlpha-2C adrenergic receptortarget
DB00408LoxapineBeta-1 adrenergic receptortarget
DB00408LoxapineMuscarinic acetylcholine receptor M1target
DB00408LoxapineMuscarinic acetylcholine receptor M2target
DB00408LoxapineMuscarinic acetylcholine receptor M3target
DB00408LoxapineMuscarinic acetylcholine receptor M4target
DB00408LoxapineMuscarinic acetylcholine receptor M5target
DB00408LoxapineD(1) dopamine receptortarget
DB00408LoxapineD(3) dopamine receptortarget
DB00408LoxapineD(4) dopamine receptortarget
DB00408LoxapineD(1B) dopamine receptortarget
DB00408LoxapineHistamine H1 receptortarget
DB00408LoxapineHistamine H2 receptortarget
DB00408LoxapineHistamine H4 receptortarget
DB00408LoxapineSodium-dependent serotonin transportertarget
DB00408LoxapineSodium-dependent noradrenaline transportertarget
DB00408LoxapineSodium-dependent dopamine transportertarget
DB08815LurasidoneCytochrome P450 3A4enzyme
DB08815LurasidoneD(2) dopamine receptortarget
DB08815Lurasidone5-hydroxytryptamine receptor 2Atarget
DB08815Lurasidone5-hydroxytryptamine receptor 7target
DB08815Lurasidone5-hydroxytryptamine receptor 1Atarget
DB08815LurasidoneAlpha-2C adrenergic receptortarget
DB08815LurasidoneAlpha-2A adrenergic receptortarget
DB01403MethotrimeprazineD(3) dopamine receptortarget
DB01403MethotrimeprazineHistamine H1 receptortarget
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M1target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M2target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M3target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M4target
DB01403MethotrimeprazineMuscarinic acetylcholine receptor M5target
DB01403MethotrimeprazineAlpha-1A adrenergic receptortarget
DB01403MethotrimeprazineAlpha-1B adrenergic receptortarget
DB01403MethotrimeprazineAlpha-1D adrenergic receptortarget
DB01403MethotrimeprazineCytochrome P450 2D6enzyme
DB01403MethotrimeprazineD(2) dopamine receptortarget
DB01403MethotrimeprazineD(1A) dopamine receptortarget
DB01403MethotrimeprazineD(1B) dopamine receptortarget
DB01403MethotrimeprazineD(4) dopamine receptortarget
DB01403MethotrimeprazineAlpha-2A adrenergic receptortarget
DB01403MethotrimeprazineAlpha-2B adrenergic receptortarget
DB01403MethotrimeprazineAlpha-2C adrenergic receptortarget
DB01403Methotrimeprazine5-hydroxytryptamine receptor 2Atarget
DB01403Methotrimeprazine5-hydroxytryptamine receptor 2Ctarget
DB01403MethotrimeprazineCytochrome P450 2E1enzyme
DB01403MethotrimeprazineCytochrome P450 1A2enzyme
DB01618MolindoneD(2) dopamine receptortarget
DB01618Molindone5-hydroxytryptamine receptor 1Atarget
DB01618Molindone5-hydroxytryptamine receptor 2Atarget
DB01618MolindoneMuscarinic acetylcholine receptor M1target
DB00540NortriptylineSodium-dependent serotonin transportertarget
DB00540NortriptylineSodium-dependent noradrenaline transportertarget
DB00540NortriptylineCytochrome P450 1A2enzyme
DB00540NortriptylineCytochrome P450 2D6enzyme
DB00540NortriptylineSerum albumincarrier
DB00540NortriptylineAlpha-1-acid glycoprotein 1carrier
DB00540NortriptylineHistamine H1 receptortarget
DB00540NortriptylineMuscarinic acetylcholine receptor M1target
DB00540NortriptylineMuscarinic acetylcholine receptor M2target
DB00540NortriptylineMuscarinic acetylcholine receptor M3target
DB00540NortriptylineMuscarinic acetylcholine receptor M4target
DB00540NortriptylineMuscarinic acetylcholine receptor M5target
DB00540Nortriptyline5-hydroxytryptamine receptor 2Atarget
DB00540NortriptylineAlpha-1A adrenergic receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Atarget
DB00540NortriptylineCytochrome P450 3A4enzyme
DB00540NortriptylineCytochrome P450 3A5enzyme
DB00540NortriptylineAlpha-1D adrenergic receptortarget
DB00540NortriptylineCytochrome P450 2C19enzyme
DB00540NortriptylineCytochrome P450 2C9enzyme
DB00540NortriptylineProstaglandin G/H synthase 1enzyme
DB00540NortriptylineCytochrome P450 2E1enzyme
DB00540Nortriptyline5-hydroxytryptamine receptor 2Ctarget
DB00540Nortriptyline5-hydroxytryptamine receptor 6target
DB00540NortriptylineAlpha-1B adrenergic receptortarget
DB00540NortriptylineAlpha-2 adrenergic receptorstarget
DB00540NortriptylineBeta adrenergic receptortarget
DB00540NortriptylineD(2) dopamine receptortarget
DB00540NortriptylineSigma receptortarget
DB00540Nortriptyline5-hydroxytryptamine receptor 1Ctarget
DB00334OlanzapineMuscarinic acetylcholine receptor M5target
DB00334OlanzapineD(1A) dopamine receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M1target
DB00334OlanzapineMuscarinic acetylcholine receptor M3target
DB00334Olanzapine5-hydroxytryptamine receptor 2Atarget
DB00334OlanzapineD(4) dopamine receptortarget
DB00334OlanzapineHistamine H1 receptortarget
DB00334OlanzapineMuscarinic acetylcholine receptor M4target
DB00334OlanzapineMuscarinic acetylcholine receptor M2target
DB00334OlanzapineD(2) dopamine receptortarget
DB00334Olanzapine5-hydroxytryptamine receptor 2Ctarget
DB00334OlanzapineD(3) dopamine receptortarget
DB00334OlanzapineAlpha-1B adrenergic receptortarget
DB00334OlanzapineCytochrome P450 1A2enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 1Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Btarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Dtarget
DB00334Olanzapine5-hydroxytryptamine receptor 1Etarget
DB00334Olanzapine5-hydroxytryptamine receptor 3Atarget
DB00334Olanzapine5-hydroxytryptamine receptor 6target
DB00334Olanzapine5-hydroxytryptamine receptor 7target
DB00334OlanzapineAlpha-1A adrenergic receptortarget
DB00334OlanzapineAlpha-2A adrenergic receptortarget
DB00334OlanzapineAlpha-2B adrenergic receptortarget
DB00334OlanzapineAlpha-2C adrenergic receptortarget
DB00334OlanzapineD(1B) dopamine receptortarget
DB00334OlanzapineSerum albumincarrier
DB00334OlanzapineAlpha-1-acid glycoprotein 1carrier
DB00334OlanzapineDimethylaniline monooxygenase [N-oxide-forming] 3enzyme
DB00334OlanzapineCytochrome P450 2D6enzyme
DB00334OlanzapineMultidrug resistance protein 1transporter
DB00334OlanzapineCytochrome P450 2C19enzyme
DB00334OlanzapineCytochrome P450 2C9enzyme
DB00334OlanzapineCytochrome P450 3A4enzyme
DB00334Olanzapine5-hydroxytryptamine receptor 2Btarget
DB00334Olanzapine5-hydroxytryptamine receptor 5Atarget
DB00334OlanzapineD(1) dopamine receptortarget
DB00334OlanzapineHistamine H2 receptortarget
DB00334OlanzapineHistamine H4 receptortarget
DB00334OlanzapineGABA-A receptor (anion channel)target
DB00334OlanzapineBeta adrenergic receptortarget
DB00334OlanzapineD(2L) dopamine receptortarget
DB00334OlanzapineD(2S) dopamine receptortarget
DB01267PaliperidoneD(2) dopamine receptortarget
DB01267Paliperidone5-hydroxytryptamine receptor 2Atarget
DB01267PaliperidoneHistamine H1 receptortarget
DB01267PaliperidoneAlpha-1A adrenergic receptortarget
DB01267PaliperidoneAlpha-1B adrenergic receptortarget
DB01267PaliperidoneD(3) dopamine receptortarget
DB01267PaliperidoneD(4) dopamine receptortarget
DB01267PaliperidoneD(1A) dopamine receptortarget
DB01267PaliperidoneAlpha-2A adrenergic receptortarget
DB01267PaliperidoneAlpha-2B adrenergic receptortarget
DB01267PaliperidoneAlpha-2C adrenergic receptortarget
DB01267Paliperidone5-hydroxytryptamine receptor 1Atarget
DB01267Paliperidone5-hydroxytryptamine receptor 1Dtarget
DB01267Paliperidone5-hydroxytryptamine receptor 2Ctarget
DB01267PaliperidoneCytochrome P450 3A4target
DB01267PaliperidoneCytochrome P450 2D6target
DB01267PaliperidoneCytochrome P450 3A5target
DB01267Paliperidone5-hydroxytryptamine receptor 7target
DB00850PerphenazineD(1A) dopamine receptortarget
DB00850PerphenazineD(2) dopamine receptortarget
DB00850PerphenazineCalmodulintarget
DB00850PerphenazineCytochrome P450 2D6enzyme
DB00850PerphenazineCytochrome P450 1A2enzyme
DB00850PerphenazineCytochrome P450 2B6enzyme
DB00850PerphenazineCytochrome P450 2C18enzyme
DB00850PerphenazineCytochrome P450 2C19enzyme
DB00850PerphenazineCytochrome P450 2C8enzyme
DB00850PerphenazineCytochrome P450 2C9enzyme
DB00850PerphenazineCytochrome P450 3A4enzyme
DB01621PipotiazineCytochrome P450 2D6enzyme
DB01621PipotiazineCytochrome P450 3A4enzyme
DB01621PipotiazineD(2) dopamine receptortarget
DB01621PipotiazineD(1A) dopamine receptortarget
DB01621Pipotiazine5-hydroxytryptamine receptor 2Atarget
DB01621Pipotiazine5-hydroxytryptamine receptor 1Atarget
DB01621PipotiazineSolute carrier family 22 member 1transporter
DB01621PipotiazineSerum albumincarrier
DB01621PipotiazineCytochrome P450 1A2enzyme
DB01621PipotiazineCytochrome P450 2C19enzyme
DB00433ProchlorperazineD(2) dopamine receptortarget
DB00433ProchlorperazineCytochrome P450 2D6enzyme
DB00433ProchlorperazineCytochrome P450 3A4enzyme
DB01224Quetiapine5-hydroxytryptamine receptor 2Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 2Ctarget
DB01224QuetiapineD(2) dopamine receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Atarget
DB01224QuetiapineHistamine H1 receptortarget
DB01224QuetiapineCytochrome P450 3A4enzyme
DB01224QuetiapineAlpha-1A adrenergic receptortarget
DB01224QuetiapineAlpha-1B adrenergic receptortarget
DB01224QuetiapineAlpha-1D adrenergic receptortarget
DB01224QuetiapineAlpha-2A adrenergic receptortarget
DB01224QuetiapineAlpha-2B adrenergic receptortarget
DB01224QuetiapineAlpha-2C adrenergic receptortarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Dtarget
DB01224QuetiapineMuscarinic acetylcholine receptor M1target
DB01224QuetiapineMuscarinic acetylcholine receptor M2target
DB01224QuetiapineMuscarinic acetylcholine receptor M3target
DB01224QuetiapineMuscarinic acetylcholine receptor M4target
DB01224QuetiapineMuscarinic acetylcholine receptor M5target
DB01224Quetiapine5-hydroxytryptamine receptor 1Btarget
DB01224Quetiapine5-hydroxytryptamine receptor 1Etarget
DB01224Quetiapine5-hydroxytryptamine receptor 3Atarget
DB01224Quetiapine5-hydroxytryptamine receptor 6target
DB01224Quetiapine5-hydroxytryptamine receptor 7target
DB01224QuetiapineD(1B) dopamine receptortarget
DB01224QuetiapineD(1A) dopamine receptortarget
DB01224QuetiapineD(3) dopamine receptortarget
DB01224QuetiapineD(4) dopamine receptortarget
DB01224QuetiapineCytochrome P450 3A5enzyme
DB01224QuetiapineCytochrome P450 3A7enzyme
DB01224QuetiapineMultidrug resistance protein 1transporter
DB01224QuetiapineCytochrome P450 2C19enzyme
DB01224QuetiapineCytochrome P450 2D6enzyme
DB00734RisperidoneHistamine H1 receptortarget
DB00734RisperidoneD(2) dopamine receptortarget
DB00734RisperidoneAlpha-1A adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 2Atarget
DB00734RisperidoneAlpha-1B adrenergic receptortarget
DB00734RisperidoneCytochrome P450 2D6enzyme
DB00734RisperidoneD(1A) dopamine receptortarget
DB00734RisperidoneAlpha-2A adrenergic receptortarget
DB00734RisperidoneAlpha-2B adrenergic receptortarget
DB00734RisperidoneAlpha-2C adrenergic receptortarget
DB00734Risperidone5-hydroxytryptamine receptor 1Atarget
DB00734Risperidone5-hydroxytryptamine receptor 1Dtarget
DB00734Risperidone5-hydroxytryptamine receptor 2Ctarget
DB00734RisperidoneD(3) dopamine receptortarget
DB00734RisperidoneD(4) dopamine receptortarget
DB00734RisperidoneCytochrome P450 3A4enzyme
DB00734RisperidoneCytochrome P450 3A5enzyme
DB00734RisperidoneCytochrome P450 3A7enzyme
DB00734RisperidoneMultidrug resistance protein 1transporter
DB00734Risperidone5-hydroxytryptamine receptor 7target
DB01622ThioproperazineD(2) dopamine receptortarget
DB01622ThioproperazineD(1A) dopamine receptortarget
DB01622Thioproperazine5-hydroxytryptamine receptor 2Atarget
DB01622Thioproperazine5-hydroxytryptamine receptor 1Atarget
DB01622ThioproperazineAlpha-1A adrenergic receptortarget
DB01622ThioproperazineAlpha-1B adrenergic receptortarget
DB01622ThioproperazineSolute carrier family 22 member 1transporter
DB01622ThioproperazineSerum albumincarrier
DB00679ThioridazineAlpha-1A adrenergic receptortarget
DB00679ThioridazineD(2) dopamine receptortarget
DB00679Thioridazine5-hydroxytryptamine receptor 2Atarget
DB00679ThioridazineD(1A) dopamine receptortarget
DB00679ThioridazineCytochrome P450 2C19enzyme
DB00679ThioridazineCytochrome P450 2D6enzyme
DB00679ThioridazineAlpha-1B adrenergic receptortarget
DB00679ThioridazinePotassium voltage-gated channel subfamily H member 2target
DB00679ThioridazineCytochrome P450 1A2enzyme
DB00679ThioridazineCytochrome P450 2C8enzyme
DB00679ThioridazineCytochrome P450 2C9enzyme
DB00679ThioridazineCytochrome P450 2E1enzyme
DB01623ThiothixeneCytochrome P450 1A2enzyme
DB01623ThiothixeneCytochrome P450 2D6enzyme
DB01623ThiothixeneD(2) dopamine receptortarget
DB01623ThiothixeneD(1A) dopamine receptortarget
DB01623Thiothixene5-hydroxytryptamine receptor 2Atarget
DB01623ThiothixeneSolute carrier family 22 member 1transporter
DB01623ThiothixeneSerum albumincarrier
DB00831TrifluoperazineD(2) dopamine receptortarget
DB00831TrifluoperazineAlpha-1A adrenergic receptortarget
DB00831TrifluoperazineNeuron-specific vesicular protein calcyontarget
DB00831TrifluoperazineXanthine dehydrogenase/oxidaseenzyme
DB00831TrifluoperazineUDP-glucuronosyltransferase 1-4enzyme
DB00831TrifluoperazineCytochrome P450 1A2enzyme
DB00831TrifluoperazineMultidrug resistance protein 1transporter
DB00831TrifluoperazineCalmodulintarget
DB00831TrifluoperazineTroponin C, slow skeletal and cardiac musclestarget
DB00831TrifluoperazineProtein S100-A4target
DB00246ZiprasidoneAlpha-1A adrenergic receptortarget
DB00246ZiprasidoneD(2) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Ctarget
DB00246ZiprasidoneD(3) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Dtarget
DB00246ZiprasidoneHistamine H1 receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 2Atarget
DB00246ZiprasidoneD(4) dopamine receptortarget
DB00246Ziprasidone5-hydroxytryptamine receptor 7target
DB00246ZiprasidoneCytochrome P450 3A4enzyme
DB00246ZiprasidoneAlpha-2A adrenergic receptortarget
DB00246ZiprasidoneAlpha-1B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2B adrenergic receptortarget
DB00246ZiprasidoneAlpha-2C adrenergic receptortarget
DB00246ZiprasidoneD(1A) dopamine receptortarget
DB00246ZiprasidoneD(1B) dopamine receptortarget
DB00246ZiprasidoneMuscarinic acetylcholine receptor M1target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M2target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M3target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M4target
DB00246ZiprasidoneMuscarinic acetylcholine receptor M5target
DB00246Ziprasidone5-hydroxytryptamine receptor 1Btarget
DB00246Ziprasidone5-hydroxytryptamine receptor 1Etarget
DB00246Ziprasidone5-hydroxytryptamine receptor 3Atarget
DB00246Ziprasidone5-hydroxytryptamine receptor 6target
DB00246ZiprasidoneCytochrome P450 3A5enzyme
DB00246ZiprasidoneCytochrome P450 3A7enzyme
DB00246ZiprasidoneCytochrome P450 1A2enzyme
DB00246ZiprasidoneCytochrome P450 2D6enzyme
DB01624ZuclopenthixolD(1A) dopamine receptortarget
DB01624ZuclopenthixolD(1B) dopamine receptortarget
DB01624ZuclopenthixolD(2) dopamine receptortarget
DB01624ZuclopenthixolCytochrome P450 2D6enzyme
DB01624ZuclopenthixolAlpha-1A adrenergic receptortarget
DB01624ZuclopenthixolAlpha-2A adrenergic receptortarget
DB01624Zuclopenthixol5-hydroxytryptamine receptor 2Atarget
DB01624ZuclopenthixolHistamine H1 receptortarget
DrugDrug NamePhaseStatusCount
DB00260Cycloserine0Enrolling by Invitation1
DB00107Oxytocin0Active Not Recruiting2
DB00107Oxytocin0Recruiting2
DB01113Papaverine0Terminated1
DB01037Selegiline0Completed1
DB05766ACP-1041Completed1
DB06151Acetylcysteine1Completed2
DB00915Amantadine1Completed1
DB06288Amisulpride1Completed1
DB06288Amisulpride1Recruiting1
DB01238Aripiprazole1Completed10
DB01238Aripiprazole1Not Yet Recruiting2
DB01238Aripiprazole1Recruiting1
DB06216Asenapine1Completed2
DB09128Brexpiprazole1Completed6
DB09128Brexpiprazole1Recruiting1
DB09061Cannabidiol1Recruiting1
DB06016Cariprazine1Completed1
DB11121Chloroxylenol1Active Not Recruiting1
DB00363Clozapine1Completed1
DB00260Cycloserine1Completed1
DB00514Dextromethorphan1Completed1
DB00470Dronabinol1Completed1
DB00470Dronabinol1Recruiting1
DB11726Encenicline1Completed1
DB05708GTS-211Completed2
DB11867JNJ-393934061Terminated1
DB12059JNJ-404118131Completed1
DB01221Ketamine1Completed4
DB01221Ketamine1Recruiting1
DB01026Ketoconazole1Completed1
DB05096LY21400231Completed2
DB08882Linagliptin1Suspended1
DB01255Lisdexamfetamine1Completed1
DB01356Lithium1Completed1
DB00186Lorazepam1Terminated1
DB08815Lurasidone1Completed5
DB00563Methotrexate1Completed1
DB01017Minocycline1Recruiting1
DB00745Modafinil1Completed1
DB00218Moxifloxacin1Completed3
DB00704Naltrexone1Completed1
DB00108Natalizumab1Active Not Recruiting1
DB00325Nitroprusside1Completed1
DB00334Olanzapine1Completed4
DB00334Olanzapine1Recruiting1
DB00904Ondansetron1Terminated1
DB00904Ondansetron1Unknown Status1
DB00107Oxytocin1Completed1
DB00107Oxytocin1Recruiting1
DB12201PF-036547461Completed1
DB11843PF-049582421Completed5
DB01267Paliperidone1Completed12
DB02789Pregnenolone1Completed1
DB01224Quetiapine1Completed2
DB01224Quetiapine1Recruiting2
DB00234Reboxetine1Unknown Status1
DB00734Risperidone1Completed12
DB00734Risperidone1Recruiting1
DB00734Risperidone1Terminated1
DB01656Roflumilast1Completed1
DB00641Simvastatin1Unknown Status1
DB11599Starch, corn1Completed1
DB06273Tocilizumab1Completed1
DB06273Tocilizumab1Recruiting1
DB00209Trospium1Completed1
DB12071Vabicaserin1Completed1
DB00313Valproic Acid1Completed1
DB01238Aripiprazole1 / 2Recruiting1
DB00289Atomoxetine1 / 2Completed1
DB01212Ceftriaxone1 / 2Unknown Status1
DB00169Cholecalciferol1 / 2Suspended1
DB00363Clozapine1 / 2Completed1
DB11672Curcumin1 / 2Unknown Status1
DB00115Cyanocobalamin1 / 2Suspended1
DB00514Dextromethorphan1 / 2Not Yet Recruiting1
DB00470Dronabinol1 / 2Terminated1
DB00158Folic Acid1 / 2Suspended1
DB01404Ginseng1 / 2Completed1
DB04946Iloperidone1 / 2Completed1
DB01043Memantine1 / 2Recruiting1
DB02701Nicotinamide1 / 2Suspended1
DB00334Olanzapine1 / 2Completed3
DB00334Olanzapine1 / 2Recruiting1
DB00107Oxytocin1 / 2Terminated1
DB00165Pyridoxine1 / 2Suspended1
DB01224Quetiapine1 / 2Recruiting1
DB00140Riboflavin1 / 2Suspended1
DB00734Risperidone1 / 2Recruiting1
DB00734Risperidone1 / 2Withdrawn1
DB00360Sapropterin1 / 2Suspended1
DB09036Siltuximab1 / 2Recruiting1
DB00152Thiamine1 / 2Suspended1
DB00162Vitamin A1 / 2Suspended1
DB00126Vitamin C1 / 2Suspended1
DB00246Ziprasidone1 / 2Recruiting1
DB05766ACP-1042Completed1
DB12145AZD-03282Terminated1
DB11692AZD-26242Completed1
DB06288Amisulpride2Completed1
DB01238Aripiprazole2Completed5
DB01238Aripiprazole2Terminated1
DB01238Aripiprazole2Unknown Status1
DB01238Aripiprazole2Withdrawn1
DB06413Armodafinil2Completed2
DB00289Atomoxetine2Completed1
DB00289Atomoxetine2Terminated1
DB05687BL-10202Completed2
DB11877Basmisanil2Recruiting1
DB06698Betahistine2Completed1
DB04888Bifeprunox2Completed3
DB12426Bitopertin2Completed1
DB06090Bradanicline2Completed2
DB09128Brexpiprazole2Completed2
DB01156Bupropion2Completed3
DB13080CYR-1012Completed1
DB09061Cannabidiol2Completed4
DB09061Cannabidiol2Recruiting3
DB00190Carbidopa2Completed1
DB06016Cariprazine2Completed4
DB00482Celecoxib2Completed1
DB00169Cholecalciferol2Withdrawn1
DB00363Clozapine2Completed1
DB03929D-Serine2Completed2
DB03929D-Serine2Unknown Status5
DB05907Davunetide2Completed1
DB01151Desipramine2Completed1
DB01576Dextroamphetamine2Recruiting1
DB00843Donepezil2Terminated1
DB12883Eltoprazine2Completed1
DB11726Encenicline2Completed1
DB12801Erteberel2Recruiting1
DB00783Estradiol2Completed3
DB08868Fingolimod2Active Not Recruiting1
DB05708GTS-212Completed1
DB00674Galantamine2Active Not Recruiting1
DB00674Galantamine2Completed1
DB00674Galantamine2Terminated1
DB09341Glucose2Completed1
DB00145Glycine2Completed3
DB00502Haloperidol2Completed1
DB10989Hepatitis A Vaccine2Completed1
DB00159Icosapent2Completed1
DB11957Idalopirdine2Completed1
DB04946Iloperidone2Completed1
DB12579JNJ-378226812Completed2
DB12059JNJ-404118132Completed1
DB05096LY21400232Completed5
DB05096LY21400232Terminated1
DB01202Levetiracetam2Withdrawn1
DB01235Levodopa2Completed1
DB06077Lumateperone2Completed2
DB08815Lurasidone2Completed5
DB12168MK-05572Completed1
DB12238MK-07772Completed2
DB00939Meclofenamic acid2Enrolling by Invitation1
DB01065Melatonin2Completed1
DB01043Memantine2Completed1
DB01043Memantine2Terminated1
DB00745Modafinil2Withdrawn1
DB11784NRX-10742Withdrawn1
DB00184Nicotine2Completed2
DB00325Nitroprusside2Completed1
DB00325Nitroprusside2Recruiting1
DB12220ORG-259352Withdrawn1
DB00334Olanzapine2Completed16
DB00334Olanzapine2Recruiting1
DB00334Olanzapine2Terminated2
DB00334Olanzapine2Withdrawn1
DB11133Omega-3 fatty acids2Completed1
DB00904Ondansetron2Completed1
DB00107Oxytocin2Active Not Recruiting1
DB00107Oxytocin2Completed2
DB00107Oxytocin2Unknown Status1
DB12998PF-002178302Completed1
DB11993PF-034632752Terminated1
DB01267Paliperidone2Completed3
DB01267Paliperidone2Terminated1
DB00686Pentosan Polysulfate2Enrolling by Invitation1
DB01186Pergolide2Suspended1
DB00850Perphenazine2Unknown Status1
DB05316Pimavanserin2Completed1
DB05316Pimavanserin2Recruiting1
DB01100Pimozide2Completed1
DB01224Quetiapine2Terminated1
DB00481Raloxifene2Completed1
DB02709Resveratrol2Completed1
DB06155Rimonabant2Terminated1
DB00734Risperidone2Completed14
DB00734Risperidone2Terminated1
DB00734Risperidone2Unknown Status1
DB00734Risperidone2Withdrawn1
DB12543Samidorphan2Completed2
DB12519Sarcosine2Completed3
DB12519Sarcosine2Withdrawn1
DB00021Secretin2Completed1
DB00641Simvastatin2Completed1
DB09072Sodium oxybate2Completed1
DB11599Starch, corn2Completed1
DB00323Tolcapone2Completed1
DB12071Vabicaserin2Completed1
DB00577Valaciclovir2Active Not Recruiting1
DB00577Valaciclovir2Completed1
DB00577Valaciclovir2Unknown Status1
DB00313Valproic Acid2Completed1
DB01273Varenicline2Completed4
DB01273Varenicline2Withdrawn1
DB12188Zicronapine2Completed2
DB00246Ziprasidone2Completed2
DB00246Ziprasidone2Terminated1
DB00945Acetylsalicylic acid2 / 3Recruiting1
DB01238Aripiprazole2 / 3Completed3
DB01238Aripiprazole2 / 3Terminated1
DB05687BL-10202 / 3Terminated1
DB04115Berberine2 / 3Not Yet Recruiting1
DB09128Brexpiprazole2 / 3Completed1
DB06016Cariprazine2 / 3Completed5
DB11695Carnosine2 / 3Recruiting1
DB00260Cycloserine2 / 3Completed1
DB00514Dextromethorphan2 / 3Completed1
DB00927Famotidine2 / 3Recruiting1
DB00674Galantamine2 / 3Completed1
DB00145Glycine2 / 3Completed1
DB00159Icosapent2 / 3Completed1
DB08887Icosapent ethyl2 / 3Completed1
DB00150L-Tryptophan2 / 3Recruiting1
DB05096LY21400232 / 3Terminated1
DB13882Methyl nicotinate2 / 3Completed1
DB00334Olanzapine2 / 3Terminated1
DB09567Olive oil2 / 3Completed1
DB00776Oxcarbazepine2 / 3Completed1
DB00213Pantoprazole2 / 3Recruiting1
DB02789Pregnenolone2 / 3Completed1
DB01224Quetiapine2 / 3Completed1
DB01224Quetiapine2 / 3Terminated1
DB00734Risperidone2 / 3Completed3
DB00734Risperidone2 / 3Terminated2
DB00246Ziprasidone2 / 3Completed1
DB00659Acamprosate3Completed1
DB00659Acamprosate3Recruiting1
DB00945Acetylsalicylic acid3Unknown Status1
DB06594Agomelatine3Recruiting1
DB00404Alprazolam3Recruiting1
DB00915Amantadine3Completed1
DB00915Amantadine3Unknown Status1
DB06288Amisulpride3Recruiting1
DB00321Amitriptyline3Recruiting1
DB01238Aripiprazole3Active Not Recruiting1
DB01238Aripiprazole3Completed25
DB01238Aripiprazole3Not Yet Recruiting2
DB01238Aripiprazole3Recruiting2
DB01238Aripiprazole3Terminated5
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DB00349Clobazam3Recruiting1
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DB01171Moclobemide3Recruiting1
DB00699Nicergoline3Recruiting1
DB01595Nitrazepam3Recruiting1
DB00540Nortriptyline3Recruiting1
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DB00334Olanzapine3Recruiting5
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DB00246Ziprasidone3Recruiting1
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DB12537BenzodiazepineNot AvailableActive Not Recruiting1
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DB00201CaffeineNot AvailableRecruiting1
DB09061CannabidiolNot AvailableNot Yet Recruiting1
DB11695CarnosineNot AvailableCompleted1
DB00438CeftazidimeNot AvailableRecruiting1
DB00482CelecoxibNot AvailableCompleted1
DB01178ChlormezanoneNot AvailableCompleted1
DB00477ChlorpromazineNot AvailableCompleted1
DB00477ChlorpromazineNot AvailableRecruiting1
DB01239ChlorprothixeneNot AvailableCompleted1
DB00169CholecalciferolNot AvailableNot Yet Recruiting1
DB00369CidofovirNot AvailableRecruiting1
DB00537CiprofloxacinNot AvailableRecruiting1
DB00215CitalopramNot AvailableCompleted1
DB00575ClonidineNot AvailableCompleted1
DB00363ClozapineNot AvailableCompleted5
DB00363ClozapineNot AvailableRecruiting4
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DB00260CycloserineNot AvailableCompleted1
DB01234DexamethasoneNot AvailableRecruiting1
DB00829DiazepamNot AvailableRecruiting1
DB00975DipyridamoleNot AvailableCompleted1
DB00450DroperidolNot AvailableRecruiting1
DB00494EntacaponeNot AvailableCompleted1
DB00153ErgocalciferolNot AvailableCompleted1
DB00402EszopicloneNot AvailableCompleted2
DB00402EszopicloneNot AvailableRecruiting1
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DB00623FluphenazineNot AvailableCompleted1
DB00623FluphenazineNot AvailableRecruiting1
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DB01320FosphenytoinNot AvailableRecruiting1
DB00014GoserelinNot AvailableCompleted1
DB00502HaloperidolNot AvailableCompleted9
DB00502HaloperidolNot AvailableRecruiting3
DB01109HeparinNot AvailableRecruiting1
DB00327HydromorphoneNot AvailableRecruiting1
DB04946IloperidoneNot AvailableRecruiting1
DB00028Immune Globulin HumanNot AvailableRecruiting1
DB00270IsradipineNot AvailableRecruiting1
DB00125L-ArginineNot AvailableCompleted2
DB00123L-LysineNot AvailableCompleted1
DB00555LamotrigineNot AvailableCompleted1
DB01202LevetiracetamNot AvailableNot Yet Recruiting1
DB01202LevetiracetamNot AvailableRecruiting2
DB00408LoxapineNot AvailableCompleted1
DB00408LoxapineNot AvailableRecruiting1
DB08815LurasidoneNot AvailableRecruiting1
DB08815LurasidoneNot AvailableUnknown Status1
DB01065MelatoninNot AvailableActive Not Recruiting1
DB01043MemantineNot AvailableRecruiting1
DB00760MeropenemNot AvailableRecruiting1
DB00933MesoridazineNot AvailableCompleted1
DB00331MetforminNot AvailableTerminated1
DB00331MetforminNot AvailableUnknown Status1
DB01403MethotrimeprazineNot AvailableCompleted1
DB00959MethylprednisoloneNot AvailableRecruiting1
DB00683MidazolamNot AvailableRecruiting1
DB01017MinocyclineNot AvailableCompleted1
DB01017MinocyclineNot AvailableUnknown Status1
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DB01618MolindoneNot AvailableRecruiting1
DB00295MorphineNot AvailableRecruiting1
DB00704NaltrexoneNot AvailableActive Not Recruiting1
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DB00622NicardipineNot AvailableRecruiting1
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DB00184NicotineNot AvailableTerminated1
DB00727NitroglycerinNot AvailableNot Yet Recruiting1
DB00334OlanzapineNot AvailableActive Not Recruiting1
DB00334OlanzapineNot AvailableCompleted10
DB00334OlanzapineNot AvailableRecruiting6
DB00334OlanzapineNot AvailableTerminated1
DB00334OlanzapineNot AvailableUnknown Status3
DB11133Omega-3 fatty acidsNot AvailableCompleted1
DB11133Omega-3 fatty acidsNot AvailableRecruiting1
DB00904OndansetronNot AvailableCompleted2
DB00198OseltamivirNot AvailableRecruiting1
DB00107OxytocinNot AvailableCompleted2
DB00107OxytocinNot AvailableRecruiting1
DB00107OxytocinNot AvailableSuspended2
DB00107OxytocinNot AvailableUnknown Status1
DB00107OxytocinNot AvailableWithdrawn1
DB01267PaliperidoneNot AvailableActive Not Recruiting1
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DB01267PaliperidoneNot AvailableRecruiting2
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DB00312PentobarbitalNot AvailableRecruiting1
DB01186PergolideNot AvailableCompleted1
DB00850PerphenazineNot AvailableCompleted3
DB00850PerphenazineNot AvailableRecruiting1
DB00981PhysostigmineNot AvailableRecruiting1
DB01100PimozideNot AvailableCompleted1
DB01100PimozideNot AvailableRecruiting1
DB01132PioglitazoneNot AvailableCompleted1
DB01621PipotiazineNot AvailableCompleted1
DB02789PregnenoloneNot AvailableCompleted1
DB00433ProchlorperazineNot AvailableRecruiting1
DB00818PropofolNot AvailableCompleted1
DB00818PropofolNot AvailableRecruiting1
DB01224QuetiapineNot AvailableCompleted8
DB01224QuetiapineNot AvailableRecruiting4
DB00740RiluzoleNot AvailableSuspended1
DB00734RisperidoneNot AvailableCompleted12
DB00734RisperidoneNot AvailableNot Yet Recruiting1
DB00734RisperidoneNot AvailableRecruiting6
DB00734RisperidoneNot AvailableSuspended1
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DB06144SertindoleNot AvailableCompleted1
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DB00641SimvastatinNot AvailableTerminated1
DB00391SulpirideNot AvailableRecruiting1
DB00444TeniposideNot AvailableActive Not Recruiting1
DB04844TetrabenazineNot AvailableCompleted2
DB01622ThioproperazineNot AvailableCompleted1
DB00679ThioridazineNot AvailableCompleted1
DB00679ThioridazineNot AvailableRecruiting1
DB01623ThiothixeneNot AvailableCompleted1
DB01623ThiothixeneNot AvailableRecruiting1
DB00373TimololNot AvailableRecruiting1
DB00684TobramycinNot AvailableRecruiting1
DB00273TopiramateNot AvailableRecruiting1
DB00831TrifluoperazineNot AvailableCompleted1
DB00831TrifluoperazineNot AvailableRecruiting1
DB00313Valproic AcidNot AvailableNot Yet Recruiting1
DB00313Valproic AcidNot AvailableRecruiting1
DB00313Valproic AcidNot AvailableUnknown Status1
DB00682WarfarinNot AvailableRecruiting1
DB00246ZiprasidoneNot AvailableCompleted7
DB00246ZiprasidoneNot AvailableRecruiting3
DB01624ZuclopenthixolNot AvailableCompleted2