Preeclampsia

Also known as: Unspecified pre-eclampsia, unspecified trimester / Toxaemia of pregnancy / Toxemia of pregnancy / Pre-eclamptic toxaemia / Pre-eclampsia toxaemia / Pre-eclampsia toxemia / Pre-Eclampsia

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidAlso known as _Aspirin_, acetylsalicylic acid (ASA) is a commonly used drug for the treatment of pain and fever due to various causes. Acetylsalicylic acid has both anti-inflammatory and antipyretic effects. This drug also inhibits platelet aggregation and is used in the prevention of blood clots stroke, and myocardial infarction (MI) [FDA label]. Interestingly, the results of various studies have demonstrated that long-term use of acetylsalicylic acid may decrease the risk of various cancers, including colorectal, esophageal, breast, lung, prostate, liver and skin cancer [A177325]. Aspirin is classified as a _non-selective cyclooxygenase (COX) inhibitor_ [A32682, A177268] and is available in many doses and forms, including chewable tablets, suppositories, extended release formulations, and others [L5968]. Acetylsalicylic acid is a very common cause of accidental poisoning in young children. It should be kept out of reach from young children, toddlers, and infants [FDA label].
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidMultidrug resistance protein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidNuclear factor kappa b beta subunittarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DrugDrug NamePhaseStatusCount
DB00335Atenolol0Recruiting2
DB00598Labetalol0Recruiting2
DB01115Nifedipine0Recruiting2
DB00107Oxytocin0Recruiting1
DB00175Pravastatin1Recruiting1
DB00917Dinoprostone1 / 2Unknown Status1
DB00929Misoprostol1 / 2Unknown Status1
DB00945Acetylsalicylic acid2Completed1
DB00126Ascorbic acid2Completed1
DB00482Celecoxib2Withdrawn1
DB11121Chloroxylenol2Completed1
DB02701Nicotinamide2Recruiting1
DB00214Torasemide2Completed1
DB00736Esomeprazole2 / 3Recruiting1
DB00598Labetalol2 / 3Withdrawn1
DB00653Magnesium sulfate2 / 3Withdrawn1
DB00396Progesterone2 / 3Unknown Status1
DB00945Acetylsalicylic acid3Completed3
DB00945Acetylsalicylic acid3Unknown Status1
DB11166Antithrombin Alfa3Completed1
DB00126Ascorbic acid3Completed2
DB14002D-alpha-Tocopherol acetate3Completed1
DB01225Enoxaparin3Completed2
DB01364Ephedrine3Withdrawn1
DB00158Folic Acid3Completed1
DB00610Metaraminol3Withdrawn1
DB00622Nicardipine3Recruiting1
DB00175Pravastatin3Not Yet Recruiting1
DB12661Urapidil3Recruiting1
DB00163Vitamin E3Completed1
DB01197Captopril4Completed1
DB00575Clonidine4Completed1
DB06779Dalteparin4Terminated1
DB00695Furosemide4Completed1
DB01050Ibuprofen4Recruiting1
DB00598Labetalol4Completed1
DB00598Labetalol4Recruiting1
DB01002Levobupivacaine4Completed1
DB00653Magnesium sulfate4Completed2
DB00653Magnesium sulfate4Not Yet Recruiting1
DB00653Magnesium sulfate4Terminated1
DB00968Methyldopa4Completed1
DB00968Methyldopa4Unknown Status2
DB01115Nifedipine4Completed1
DB01115Nifedipine4Recruiting1
DB09153Sodium chloride4Completed1
DB00945Acetylsalicylic acidNot AvailableCompleted1
DB00945Acetylsalicylic acidNot AvailableRecruiting2
DB00945Acetylsalicylic acidNot AvailableTerminated2
DB01373CalciumNot AvailableUnknown Status1
DB01225EnoxaparinNot AvailableCompleted1
DB01364EphedrineNot AvailableCompleted1
DB01364EphedrineNot AvailableUnknown Status1
DB00736EsomeprazoleNot AvailableRecruiting1
DB01029IrbesartanNot AvailableSuspended1
DB01020Isosorbide MononitrateNot AvailableRecruiting1
DB00653Magnesium sulfateNot AvailableCompleted1
DB00653Magnesium sulfateNot AvailableNot Yet Recruiting1
DB00653Magnesium sulfateNot AvailableRecruiting1
DB00610MetaraminolNot AvailableUnknown Status1
DB00107OxytocinNot AvailableCompleted1
DB00388PhenylephrineNot AvailableCompleted1
DB00388PhenylephrineNot AvailableUnknown Status1
DB00396ProgesteroneNot AvailableTerminated1
DB00203SildenafilNot AvailableRecruiting1