Anemias

Also known as: Anemia / Anaemia / Anaemia, unspecified / Unspecified anaemia / Unspecified anemia / Anemia, unspecified / Anaemia NOS

DrugDrug NameDrug Description
DB00012Darbepoetin alfaHuman erythropoietin with 2 aa substitutions to enhance glycosylation (5 N-linked chains), 165 residues (MW=37 kD). Produced in Chinese hamster ovary (CHO) cells by recombinant DNA technology.
DB11624Epoetin deltaEpoetin Delta is an ingredient in the EMA-withdrawn product Dynepo.
DB00016ErythropoietinErythropoietin (EPO) is a growth factor produced in the kidneys that stimulates the production of red blood cells. It works by promoting the division and differentiation of committed erythroid progenitors in the bone marrow [FDA Label]. Epoetin alfa (Epoge) was developed by Amgen Inc. in 1983 as the first rhEPO commercialized in the United States, followed by other alfa and beta formulations. Epoetin alfa is a 165-amino acid erythropoiesis-stimulating glycoprotein produced in cell culture using recombinant DNA technology and is used for the treatment of patients with anemia associated with various clinical conditions, such as chronic renal failure, antiviral drug therapy, chemotherapy, or a high risk for perioperative blood loss from surgical procedures [FDA Label]. It has a molecular weight of approximately 30,400 daltons and is produced by mammalian cells into which the human erythropoietin gene has been introduced. The product contains the identical amino acid sequence of isolated natural erythropoietin and has the same biological activity as the endogenous erythropoietin. Epoetin alfa biosimilar, such as Retacrit (epoetin alfa-epbx or epoetin zeta), has been formulated to allow more access to treatment options for patients in the market [L2784]. The biosimilar is approved by the FDA and EMA as a safe, effective and affordable biological product and displays equivalent clinical efficacy, potency, and purity to the reference product [A7504]. Epoetin alfa formulations can be administered intravenously or subcutaneously.
DB09107Methoxy polyethylene glycol-epoetin betaMethoxy polyethylene glycol-epoetin beta is a chemically synthesised Erythropoiesis Stimulating Agent (ESA) with a longer half-life than erythropoietin. ESA is used to increase synthesis of red blood cells to treat chronic kidney disease associated anemia.
DB09517Sodium ferric gluconate complexSodium ferric gluconate complex is an iron replacement product for treatment of iron deficiency anemia. The stable macromolecular complex is negatively charged at alkaline pH with an apparent molecular weight of 289,000 – 440,000 daltons on gel chromatography. It is composed of iron (III) oxide hydrate directly bonded to sucrose with a chelating gluconate function in a molar ratio of two iron molecules to one gluconate. It is used in adult and in pediatric patients over the age of 6 years with chronic kidney disease (CKD) receiving hemodialysis and receiving supplemental epoetin therapy.
DrugDrug NamePhaseStatusCount
DB03496Alvocidib1Completed1
DB00201Caffeine1Completed1
DB08889Carfilzomib1Recruiting1
DB00091Ciclosporin1Completed1
DB11682Daprodustat1Completed8
DB11682Daprodustat1Terminated1
DB00012Darbepoetin alfa1Withdrawn1
DB01234Dexamethasone1Recruiting1
DB00016Erythropoietin1Completed2
DB09147Ferric pyrophosphate1Not Yet Recruiting1
DB06215Ferumoxytol1Completed1
DB00712Flurbiprofen1Completed1
DB01241Gemfibrozil1Completed1
DB12208Iron isomaltoside 10001Completed1
DB00480Lenalidomide1Completed1
DB12578Lexaptepid Pegol1Completed1
DB12281Luspatercept1Completed1
DB00331Metformin1Active Not Recruiting1
DB00683Midazolam1Completed1
DB00218Moxifloxacin1Completed2
DB00338Omeprazole1Completed1
DB08894Peginesatide1Completed1
DB08894Peginesatide1Terminated1
DB01132Pioglitazone1Completed1
DB00503Ritonavir1Active Not Recruiting1
DB00412Rosiglitazone1Completed1
DB01098Rosuvastatin1Completed1
DB04847Roxadustat1Completed1
DB00440Trimethoprim1Completed1
DB00087Alemtuzumab1 / 2Terminated1
DB09312Antilymphocyte immunoglobulin (horse)1 / 2Terminated1
DB00098Antithymocyte immunoglobulin (rabbit)1 / 2Terminated1
DB01008Busulfan1 / 2Terminated1
DB11121Chloroxylenol1 / 2Not Yet Recruiting1
DB00531Cyclophosphamide1 / 2Terminated1
DB00012Darbepoetin alfa1 / 2Completed1
DB12121Entospletinib1 / 2Recruiting1
DB00016Erythropoietin1 / 2Recruiting1
DB06215Ferumoxytol1 / 2Recruiting1
DB01073Fludarabine1 / 2Terminated1
DB01320Fosphenytoin1 / 2Terminated1
DB04335Inosine1 / 2Not Yet Recruiting1
DB00825Levomenthol1 / 2Terminated1
DB12578Lexaptepid Pegol1 / 2Completed1
DB01042Melphalan1 / 2Terminated1
DB08935Obinutuzumab1 / 2Recruiting1
DB00252Phenytoin1 / 2Terminated1
DB04572Thiotepa1 / 2Terminated1
DB00163Vitamin E1 / 2Completed1
DB03128Acetylcholine2Recruiting1
DB01143Amifostine2Unknown Status1
DB11720Angiotensin 1-72Completed1
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB01008Busulfan2Recruiting1
DB01008Busulfan2Withdrawn1
DB00493Cefotaxime2Recruiting1
DB11121Chloroxylenol2Completed1
DB00091Ciclosporin2Completed2
DB00515Cisplatin2Completed1
DB00115Cyanocobalamin2Unknown Status1
DB00531Cyclophosphamide2Recruiting1
DB00987Cytarabine2Completed1
DB01406Danazol2Completed1
DB11682Daprodustat2Completed7
DB11682Daprodustat2Not Yet Recruiting1
DB11682Daprodustat2Recruiting2
DB00012Darbepoetin alfa2Completed21
DB00012Darbepoetin alfa2Not Yet Recruiting1
DB00012Darbepoetin alfa2Recruiting1
DB00012Darbepoetin alfa2Terminated4
DB00694Daunorubicin2Completed1
DB01609Deferasirox2Completed1
DB01609Deferasirox2Recruiting1
DB01248Docetaxel2Completed1
DB06210Eltrombopag2Recruiting1
DB00016Erythropoietin2Completed30
DB00016Erythropoietin2Recruiting4
DB00016Erythropoietin2Terminated11
DB00016Erythropoietin2Unknown Status2
DB00016Erythropoietin2Withdrawn3
DB08917Ferric carboxymaltose2Recruiting1
DB06215Ferumoxytol2Completed1
DB00099Filgrastim2Completed1
DB00099Filgrastim2Withdrawn1
DB01073Fludarabine2Recruiting1
DB01073Fludarabine2Withdrawn1
DB00158Folic Acid2Unknown Status1
DB01592Iron2Completed2
DB01592Iron2Recruiting1
DB01592Iron2Unknown Status1
DB00893Iron Dextran2Completed1
DB06790Iron saccharate2Completed1
DB09146Iron saccharate2Completed2
DB09146Iron saccharate2Terminated2
DB09146Iron saccharate2Withdrawn1
DB00480Lenalidomide2Recruiting1
DB00848Levamisole2Unknown Status1
DB12281Luspatercept2Completed1
DB12281Luspatercept2Recruiting1
DB00563Methotrexate2Withdrawn1
DB09107Methoxy polyethylene glycol-epoetin beta2Active Not Recruiting1
DB09107Methoxy polyethylene glycol-epoetin beta2Completed6
DB09107Methoxy polyethylene glycol-epoetin beta2Recruiting1
DB00688Mycophenolate mofetil2Completed1
DB00325Nitroprusside2Recruiting1
DB00104Octreotide2Active Not Recruiting1
DB00621Oxandrolone2Withdrawn1
DB00019Pegfilgrastim2Completed1
DB08894Peginesatide2Completed7
DB08894Peginesatide2Terminated3
DB00022Peginterferon alfa-2b2Terminated1
DB00635Prednisone2Unknown Status1
DB00811Ribavirin2Completed2
DB12146Rigosertib2Recruiting1
DB06372Rilonacept2Withdrawn1
DB04847Roxadustat2Completed4
DB06164Ruxolitinib2Completed1
DB08877Ruxolitinib2Completed1
DB01399Salsalate2Terminated1
DB09517Sodium ferric gluconate complex2Withdrawn1
DB05995Sotatercept2Completed2
DB12118Sotatercept2Completed3
DB12118Sotatercept2Terminated1
DB00864Tacrolimus2Withdrawn1
DB01041Thalidomide2Completed1
DB11815Tilarginine2Recruiting1
DB12255Vadadustat2Completed6
DB12255Vadadustat2Recruiting1
DB12255Vadadustat2Terminated1
DB00518Albendazole2 / 3Completed1
DB11121Chloroxylenol2 / 3Completed1
DB11682Daprodustat2 / 3Completed1
DB00012Darbepoetin alfa2 / 3Terminated1
DB00016Erythropoietin2 / 3Completed1
DB11067Heme iron polypeptide2 / 3Completed1
DB09146Iron saccharate2 / 3Completed1
DB14158Microcrystalline cellulose2 / 3Not Yet Recruiting1
DB00104Octreotide2 / 3Recruiting1
DB06589Pazopanib2 / 3Not Yet Recruiting1
DB04847Roxadustat2 / 3Enrolling by Invitation1
DB00126Ascorbic acid3Completed1
DB00126Ascorbic acid3Recruiting1
DB00126Ascorbic acid3Unknown Status1
DB00207Azithromycin3Completed1
DB01373Calcium3Completed4
DB00493Cefotaxime3Active Not Recruiting1
DB00608Chloroquine3Withdrawn1
DB00169Cholecalciferol3Completed1
DB00169Cholecalciferol3Unknown Status1
DB00515Cisplatin3Completed2
DB00115Cyanocobalamin3Completed1
DB00115Cyanocobalamin3Unknown Status1
DB00531Cyclophosphamide3Active Not Recruiting1
DB11682Daprodustat3Active Not Recruiting1
DB11682Daprodustat3Completed1
DB11682Daprodustat3Recruiting4
DB00012Darbepoetin alfa3Active Not Recruiting1
DB00012Darbepoetin alfa3Completed26
DB00012Darbepoetin alfa3Recruiting6
DB00012Darbepoetin alfa3Terminated5
DB00012Darbepoetin alfa3Withdrawn2
DB01234Dexamethasone3Completed1
DB11624Epoetin delta3Terminated1
DB00016Erythropoietin3Active Not Recruiting2
DB00016Erythropoietin3Completed43
DB00016Erythropoietin3Terminated10
DB00016Erythropoietin3Unknown Status1
DB00016Erythropoietin3Withdrawn1
DB00783Estradiol3Recruiting1
DB08917Ferric carboxymaltose3Active Not Recruiting1
DB08917Ferric carboxymaltose3Completed12
DB08917Ferric carboxymaltose3Terminated2
DB11210Ferrous bisglycinate3Completed1
DB13257Ferrous sulfate anhydrous3Recruiting1
DB06215Ferumoxytol3Completed1
DB00099Filgrastim3Completed1
DB01073Fludarabine3Active Not Recruiting1
DB00158Folic Acid3Completed1
DB00158Folic Acid3Unknown Status1
DB00828Fosfomycin3Completed5
DB00014Goserelin3Recruiting1
DB09053Ibrutinib3Active Not Recruiting1
DB01592Iron3Active Not Recruiting1
DB01592Iron3Completed10
DB01592Iron3Recruiting4
DB00893Iron Dextran3Completed1
DB12208Iron isomaltoside 10003Completed1
DB12208Iron isomaltoside 10003Recruiting1
DB09146Iron saccharate3Completed6
DB09146Iron saccharate3Withdrawn1
DB00125L-Arginine3Completed1
DB00480Lenalidomide3Active Not Recruiting1
DB00480Lenalidomide3Completed1
DB00643Mebendazole3Completed1
DB00643Mebendazole3Unknown Status1
DB06279Methoxy polyethylene glycol-epoetin beta3Completed2
DB09107Methoxy polyethylene glycol-epoetin beta3Completed34
DB09107Methoxy polyethylene glycol-epoetin beta3Terminated6
DB09107Methoxy polyethylene glycol-epoetin beta3Withdrawn1
DB00929Misoprostol3Completed1
DB02701Nicotinamide3Completed1
DB02701Nicotinamide3Unknown Status1
DB08894Peginesatide3Completed5
DB00635Prednisone3Withdrawn1
DB00165Pyridoxine3Completed1
DB00165Pyridoxine3Unknown Status1
DB00140Riboflavin3Completed1
DB00140Riboflavin3Unknown Status1
DB00073Rituximab3Active Not Recruiting1
DB04847Roxadustat3Active Not Recruiting2
DB04847Roxadustat3Completed3
DB14482Sodium ascorbate3Recruiting1
DB09153Sodium chloride3Completed1
DB09153Sodium chloride3Terminated1
DB09517Sodium ferric gluconate complex3Completed1
DB05253Telapristone acetate3Terminated2
DB00152Thiamine3Completed1
DB00152Thiamine3Unknown Status1
DB06822Tinzaparin3Recruiting1
DB00302Tranexamic acid3Recruiting2
DB12255Vadadustat3Recruiting3
DB12255Vadadustat3Withdrawn1
DB00162Vitamin A3Completed1
DB00162Vitamin A3Unknown Status1
DB06151Acetylcysteine4Unknown Status1
DB00518Albendazole4Completed1
DB06697Artemether4Completed1
DB09274Artesunate4Completed1
DB00126Ascorbic acid4Completed1
DB00126Ascorbic acid4Terminated1
DB00136Calcitriol4Completed1
DB01373Calcium4Unknown Status1
DB01282Carbetocin4Completed1
DB01012Cinacalcet4Completed1
DB00515Cisplatin4Completed1
DB00115Cyanocobalamin4Terminated1
DB00531Cyclophosphamide4Completed1
DB00012Darbepoetin alfa4Completed10
DB01609Deferasirox4Completed1
DB11624Epoetin delta4Terminated1
DB00153Ergocalciferol4Withdrawn1
DB00016Erythropoietin4Completed24
DB00016Erythropoietin4Not Yet Recruiting1
DB00016Erythropoietin4Recruiting3
DB00016Erythropoietin4Terminated11
DB08917Ferric carboxymaltose4Completed4
DB08917Ferric carboxymaltose4Not Yet Recruiting1
DB08917Ferric carboxymaltose4Recruiting2
DB09147Ferric pyrophosphate4Not Yet Recruiting1
DB11169Ferrous asparto glycinate4Terminated1
DB00099Filgrastim4Completed1
DB00158Folic Acid4Terminated1
DB09349Gastric intrinsic factor4Terminated1
DB01592Iron4Completed3
DB01592Iron4Recruiting4
DB01592Iron4Unknown Status3
DB00893Iron Dextran4Terminated1
DB12208Iron isomaltoside 10004Recruiting1
DB09146Iron saccharate4Active Not Recruiting1
DB06790Iron saccharate4Completed1
DB09146Iron saccharate4Completed6
DB00583Levocarnitine4Unknown Status1
DB11256Levomefolic acid4Terminated1
DB06708Lumefantrine4Completed1
DB09107Methoxy polyethylene glycol-epoetin beta4Completed10
DB09107Methoxy polyethylene glycol-epoetin beta4Terminated2
DB00107Oxytocin4Completed1
DB00910Paricalcitol4Completed1
DB00910Paricalcitol4Recruiting1
DB08894Peginesatide4Terminated1
DB00008Peginterferon alfa-2a4Completed1
DB00468Quinine4Completed1
DB00811Ribavirin4Completed1
DB09153Sodium chloride4Not Yet Recruiting1
DB09153Sodium chloride4Recruiting1
DB09517Sodium ferric gluconate complex4Completed1
DB09517Sodium ferric gluconate complex4Unknown Status1
DB00139Succinic acid4Terminated1
DB01015Sulfamethoxazole4Completed1
DB04572Thiotepa4Completed1
DB00302Tranexamic acid4Recruiting1
DB00302Tranexamic acid4Terminated1
DB00440Trimethoprim4Completed1
DB00162Vitamin A4Completed1
DB01593Zinc4Terminated1
DB00518AlbendazoleNot AvailableCompleted1
DB00518AlbendazoleNot AvailableUnknown Status2
DB00613AmodiaquineNot AvailableCompleted1
DB01373CalciumNot AvailableActive Not Recruiting1
DB01373CalciumNot AvailableCompleted1
DB01373CalciumNot AvailableWithdrawn1
DB00608ChloroquineNot AvailableCompleted1
DB00608ChloroquineNot AvailableTerminated1
DB00012Darbepoetin alfaNot AvailableActive Not Recruiting1
DB00012Darbepoetin alfaNot AvailableCompleted3
DB00012Darbepoetin alfaNot AvailableTerminated1
DB01609DeferasiroxNot AvailableCompleted1
DB12362Diaminopropanol tetraacetic acidNot AvailableRecruiting2
DB11624Epoetin deltaNot AvailableTerminated1
DB00016ErythropoietinNot AvailableCompleted4
DB00016ErythropoietinNot AvailableRecruiting1
DB00016ErythropoietinNot AvailableTerminated1
DB00016ErythropoietinNot AvailableUnknown Status2
DB00016ErythropoietinNot AvailableWithdrawn1
DB00927FamotidineNot AvailableCompleted1
DB13949Ferric cationNot AvailableActive Not Recruiting1
DB00158Folic AcidNot AvailableCompleted1
DB01592IronNot AvailableActive Not Recruiting1
DB01592IronNot AvailableCompleted4
DB01592IronNot AvailableNot Yet Recruiting1
DB01592IronNot AvailableRecruiting1
DB01592IronNot AvailableTerminated1
DB01592IronNot AvailableWithdrawn1
DB12208Iron isomaltoside 1000Not AvailableCompleted1
DB12208Iron isomaltoside 1000Not AvailableRecruiting2
DB09146Iron saccharateNot AvailableCompleted1
DB09146Iron saccharateNot AvailableRecruiting1
DB00480LenalidomideNot AvailableCompleted1
DB09107Methoxy polyethylene glycol-epoetin betaNot AvailableCompleted4
DB00929MisoprostolNot AvailableCompleted1
DB11133Omega-3 fatty acidsNot AvailableEnrolling by Invitation1
DB08894PeginesatideNot AvailableRecruiting1
DB01058PraziquantelNot AvailableCompleted1
DB01058PraziquantelNot AvailableUnknown Status1
DB09153Sodium chlorideNot AvailableCompleted1
DB09153Sodium chlorideNot AvailableTerminated1
DB00302Tranexamic acidNot AvailableNot Yet Recruiting1
DB00302Tranexamic acidNot AvailableTerminated1