Posttraumatic Stress Disorders

Also known as: Posttraumatic Stress Disorder / Stress Disorder, Posttraumatic / Traumatic neurosis / Post-traumatic stress disorder / Post-traumatic stress disorder, unspecified / Stress Disorders, Post-Traumatic

DrugDrug NameDrug Description
DB00734RisperidoneSchizophrenia and various mood disorders are thought to be caused by an excess of dopaminergic D2 and serotonergic 5-HT2A activity, resulting in overactivity of central mesolimbic pathways and mesocortical pathways, respectively [L1212, L1213]. Risperidone inhibits dopaminergic D2 receptors and serotonergic 5-HT2A receptors in the brain. It is also said to block histamine receptors, and other neural receptors which are currently being studied [L1213, A1115]. Risperidone binds with a very high affinity to 5-HT2A receptors, approximately 10-20 fold greater than the drug's binding affinity to D2 receptors [L1212, L1213, A1115].
DrugDrug NamePhaseStatusCount
DB00476Duloxetine0Completed1
DB00107Oxytocin0Recruiting1
DB11788Neuropeptide Y1Completed1
DB08954Ifenprodil1 / 2Recruiting1
DB01454Midomafetamine1 / 2Completed1
DB06151Acetylcysteine2Withdrawn1
DB00673Aprepitant2Completed1
DB09061Cannabidiol2Recruiting1
DB00260Cycloserine2Unknown Status2
DB03929D-Serine2Completed1
DB00590Doxazosin2Recruiting1
DB00470Dronabinol2Recruiting1
DB01175Escitalopram2Unknown Status1
DB01175Escitalopram2Withdrawn1
DB06717Fosaprepitant2Completed1
DB00674Galantamine2Terminated1
DB01221Ketamine2Recruiting2
DB14009Medical Cannabis2Recruiting1
DB00422Methylphenidate2Terminated1
DB00683Midazolam2Recruiting1
DB01454Midomafetamine2Active Not Recruiting1
DB01454Midomafetamine2Completed6
DB01454Midomafetamine2Recruiting1
DB01454Midomafetamine2Terminated1
DB00834Mifepristone2Recruiting1
DB12979Nepicastat2Completed1
DB00107Oxytocin2Recruiting1
DB01708Prasterone2Not Yet Recruiting1
DB00457Prazosin2Unknown Status1
DB02789Pregnenolone2Not Yet Recruiting1
DB00571Propranolol2Terminated1
DB00571Propranolol2Unknown Status1
DB00745Modafinil2 / 3Unknown Status1
DB00571Propranolol2 / 3Recruiting1
DB00273Topiramate2 / 3Completed1
DB01238Aripiprazole3Completed1
DB00476Duloxetine3Unknown Status1
DB01454Midomafetamine3Recruiting1
DB00457Prazosin3Recruiting1
DB06216Asenapine4Completed1
DB00829Diazepam4Unknown Status1
DB00470Dronabinol4Recruiting1
DB00470Dronabinol4Unknown Status1
DB00402Eszopiclone4Completed1
DB00813Fentanyl4Terminated1
DB00588Fluticasone propionate4Terminated1
DB00741Hydrocortisone4Completed1
DB01221Ketamine4Terminated1
DB00834Mifepristone4Completed1
DB00370Mirtazapine4Completed1
DB00107Oxytocin4Completed1
DB01267Paliperidone4Withdrawn1
DB00715Paroxetine4Completed1
DB00571Propranolol4Completed1
DB00571Propranolol4Terminated1
DB01104Sertraline4Completed3
DB09034Suvorexant4Recruiting2
DB00273Topiramate4Completed1
DB00285Venlafaxine4Withdrawn1
DB00246Ziprasidone4Completed1
DB00215CitalopramNot AvailableRecruiting1
DB00260CycloserineNot AvailableCompleted1
DB00260CycloserineNot AvailableRecruiting1
DB01234DexamethasoneNot AvailableCompleted2
DB01075DiphenhydramineNot AvailableRecruiting1
DB00476DuloxetineNot AvailableRecruiting1
DB00472FluoxetineNot AvailableNot Yet Recruiting1
DB00472FluoxetineNot AvailableRecruiting1
DB00176FluvoxamineNot AvailableRecruiting1
DB00741HydrocortisoneNot AvailableCompleted1
DB00741HydrocortisoneNot AvailableTerminated1
DB00741HydrocortisoneNot AvailableUnknown Status1
DB00678LosartanNot AvailableRecruiting1
DB00370MirtazapineNot AvailableRecruiting1
DB00184NicotineNot AvailableRecruiting1
DB11133Omega-3 fatty acidsNot AvailableActive Not Recruiting1
DB00107OxytocinNot AvailableCompleted1
DB00715ParoxetineNot AvailableRecruiting1
DB00252PhenytoinNot AvailableUnknown Status1
DB00457PrazosinNot AvailableRecruiting1
DB00457PrazosinNot AvailableWithdrawn1
DB00571PropranololNot AvailableCompleted1
DB00571PropranololNot AvailableUnknown Status1
DB00296RopivacaineNot AvailableCompleted1
DB01104SertralineNot AvailableCompleted1
DB00877SirolimusNot AvailableCompleted1
DB09153Sodium ChlorideNot AvailableCompleted1
DB00273TopiramateNot AvailableTerminated1
DB00656TrazodoneNot AvailableRecruiting1
DB00285VenlafaxineNot AvailableRecruiting1
DB01593ZincNot AvailableRecruiting1