Also known as: Deaths / Death / Mortalities / O/E - dead / Death NOS

DrugDrug NameDrug Description
DB06681BelataceptBelatacept is a soluble fusion protein, which links the extracellular domain of human cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4) to the modified Fc (hinge, CH2, and CH3 domains) portion of human immunoglobulin G1 (IgG1). Structurally, abatacept is a glycosylated fusion protein with a MALDI-MS molecular weight of 92,300 Da and it is a homodimer of two homologous polypeptide chains of 357 amino acids each. It is produced through recombinant DNA technology in mammalian CHO cells. The drug has activity as a selective co-stimulation modulator with inhibitory activity on T lymphocytes. It is approved for the treatment of rheumatoid arthritis. Belatacept selectively blocks the process of T-cell activation. It was developed by Bristol-Myers-Squibb. It differs from abatacept (Orencia) by only 2 amino acids. FDA approved on June 15, 2011.
DB00177ValsartanValsartan is an angiotensin-receptor blocker (ARB) that may be used to treat a variety of cardiac conditions including hypertension, diabetic nephropathy and heart failure. Valsartan lowers blood pressure by antagonizing the renin-angiotensin-aldosterone system (RAAS); it competes with angiotensin II for binding to the type-1 angiotensin II receptor (AT1) subtype and prevents the blood pressure increasing effects of angiotensin II. Unlike angiotensin-converting enzyme (ACE) inhibitors, ARBs do not have the adverse effect of dry cough. Valsartan may be used to treat hypertension, isolated systolic hypertension, left ventricular hypertrophy and diabetic nephropathy. It may also be used as an alternative agent for the treatment of heart failure, systolic dysfunction, myocardial infarction and coronary artery disease.
DrugDrug NamePhaseStatusCount
DB00126Ascorbic acid2 / 3Completed1
DB00169Cholecalciferol2 / 3Completed1
DB00115Cyanocobalamin2 / 3Completed1
DB00158Folic Acid2 / 3Completed1
DB00741Hydrocortisone2 / 3Unknown Status1
DB02701Nicotinamide2 / 3Completed1
DB00165Pyridoxine2 / 3Completed1
DB00140Riboflavin2 / 3Completed1
DB00152Thiamine2 / 3Completed1
DB00162Vitamin A2 / 3Completed1
DB04899Nesiritide3Unknown Status1
DB11248Zinc gluconate3Completed1
DB12768BCG vaccine4Recruiting1
DB09153Sodium Chloride4Completed1
DB09153Sodium Chloride4Recruiting1
DB00162Vitamin A4Completed3
DB00162Vitamin A4Terminated1
DB00162Vitamin A4Unknown Status1
DB047895-methyltetrahydrofolic acidNot AvailableCompleted1
DB13152Coagulation Factor IX HumanNot AvailableRecruiting1
DB00633DexmedetomidineNot AvailableActive Not Recruiting1
DB00736EsomeprazoleNot AvailableUnknown Status1
DB00158Folic AcidNot AvailableCompleted1
DB01024Mycophenolic acidNot AvailableNot Yet Recruiting1
DB09153Sodium ChlorideNot AvailableActive Not Recruiting1
DB00864TacrolimusNot AvailableNot Yet Recruiting1
DB00302Tranexamic AcidNot AvailableUnknown Status1
DB01593ZincNot AvailableCompleted2