Hurler's Syndrome

Also known as: Hurler Syndrome / Dysostosis multiplex / MPS I H / Hurler's disease / Mucopolysaccharidosis I

DrugDrug NameDrug Description
DB00090LaronidaseHuman recombinant alpha-L-iduronidase, 628 residues (mature form), produced by recombinant DNAtechnology in a Chinese hamster ovary cell line. Laronidase is a glycoprotein with a molecular weight of approximately 83 kD. The predicted amino acid sequence of the recombinant form, as well as the nucleotide sequence that encodes it, are identical to a polymorphic form of human a-L-iduronidase. It contains 6 N-linked oligosaccharide modification sites.
DrugDrug NameTargetType
DB00090LaronidaseIduronic acidtarget
DrugDrug NamePhaseStatusCount
DB01281Abatacept1Recruiting1
DB00090Laronidase1Active Not Recruiting1
DB00090Laronidase1Completed1
DB00087Alemtuzumab2Completed1
DB01008Busulfan2Completed1
DB01008Busulfan2Terminated1
DB00091Ciclosporin2Completed1
DB00531Cyclophosphamide2Completed1
DB00531Cyclophosphamide2Terminated1
DB00125L-Arginine2Completed1
DB00090Laronidase2Completed2
DB00688Mycophenolate mofetil2Completed1
DB00090Laronidase3Completed2
DB00090Laronidase4Completed2
DB00090Laronidase4Recruiting1
DB04974AP1903Not AvailableAvailable1
DB00090LaronidaseNot AvailableTerminated1
DB00082PegvisomantNot AvailableWithdrawn1