Central Nervous System Lymphoma

Also known as: CNS Lymphoma

DrugDrug NameDrug Description
DB00563MethotrexateAn antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of tetrahydrofolate dehydrogenase and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
DrugDrug NameTargetType
DB00563MethotrexateDihydrofolate reductasetarget
DB00563MethotrexateAldehyde oxidaseenzyme
DB00563MethotrexateMethylenetetrahydrofolate reductaseenzyme
DB00563MethotrexateSerum albumincarrier
DB00563MethotrexateCanalicular multispecific organic anion transporter 2transporter
DB00563MethotrexateMultidrug resistance-associated protein 4transporter
DB00563MethotrexateMultidrug resistance-associated protein 1transporter
DB00563MethotrexateSolute carrier family 22 member 6transporter
DB00563MethotrexateMultidrug resistance-associated protein 7transporter
DB00563MethotrexateSolute carrier family 22 member 8transporter
DB00563MethotrexateCanalicular multispecific organic anion transporter 1transporter
DB00563MethotrexateMultidrug resistance protein 1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1A2transporter
DB00563MethotrexateMonocarboxylate transporter 1transporter
DB00563MethotrexateATP-binding cassette sub-family C member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B3transporter
DB00563MethotrexateSolute carrier family 22 member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1C1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 3A1transporter
DB00563MethotrexateATP-binding cassette sub-family G member 2transporter
DB00563MethotrexateSolute carrier family 22 member 7transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B1transporter
DB00563Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00563MethotrexateProton-coupled folate transportertransporter
DB00563MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB00563MethotrexateGamma-glutamyl hydrolaseenzyme
DB00563MethotrexateDihydrofolate reductaseenzyme
DB00563MethotrexateThymidylate synthaseenzyme
DB00563MethotrexateBifunctional purine biosynthesis protein PURHenzyme
DB00563MethotrexateSolute carrier organic anion transporter family member 4C1transporter
DB00563MethotrexateFolate transporter 1transporter
DB00563MethotrexateFolate receptor alphatransporter
DrugDrug NamePhaseStatusCount
DB01234Dexamethasone1Suspended1
DB00563Methotrexate1Completed1
DB00642Pemetrexed1Completed1
DB08910Pomalidomide1Suspended1
DB00073Rituximab1Completed1
DB00958Carboplatin1 / 2Recruiting1
DB00742Mannitol1 / 2Recruiting1
DB00563Methotrexate1 / 2Recruiting1
DB00073Rituximab1 / 2Recruiting1
DB09499Thiosulfuric acid1 / 2Recruiting1
DB00262Carmustine2Completed1
DB00987Cytarabine2Completed1
DB09053Ibrutinib2Recruiting1
DB00563Methotrexate2Completed2
DB08935Obinutuzumab2Recruiting1
DB00073Rituximab2Completed1
DB04572Thiotepa2Completed1
DB00563Methotrexate4Completed1
DB12091GadoliniumNot AvailableActive Not Recruiting1
DB06215ferumoxytolNot AvailableActive Not Recruiting1