Central Nervous System Lymphoma

Also known as: Lymphoma Cns / CNS Lymphoma / Malignant lymphoma, no ICD-O subtype (morphologic abnormality) / Primary central nervous system lymphoma / Microglioma (disorder) / Microglioma -RETIRED- / [M]Microglioma (morphologic abnormality)

DrugDrug NameDrug Description
DB00563MethotrexateAn antineoplastic agent used the treatment of a wide variety of cancers as well as severe psoriasis, severe rheumatoid arthritis, and juvenile rheumatoid arthritis.
DrugDrug NameTargetType
DB00563MethotrexateDihydrofolate reductasetarget
DB00563MethotrexateAldehyde oxidaseenzyme
DB00563MethotrexateMethylenetetrahydrofolate reductaseenzyme
DB00563MethotrexateSerum albumincarrier
DB00563MethotrexateCanalicular multispecific organic anion transporter 2transporter
DB00563MethotrexateMultidrug resistance-associated protein 4transporter
DB00563MethotrexateMultidrug resistance-associated protein 1transporter
DB00563MethotrexateSolute carrier family 22 member 6transporter
DB00563MethotrexateMultidrug resistance-associated protein 7transporter
DB00563MethotrexateSolute carrier family 22 member 8transporter
DB00563MethotrexateCanalicular multispecific organic anion transporter 1transporter
DB00563MethotrexateP-glycoprotein 1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1A2transporter
DB00563MethotrexateMonocarboxylate transporter 1transporter
DB00563MethotrexateATP-binding cassette sub-family C member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B3transporter
DB00563MethotrexateSolute carrier family 22 member 11transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1C1transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 3A1transporter
DB00563MethotrexateATP-binding cassette sub-family G member 2transporter
DB00563MethotrexateSolute carrier family 22 member 7transporter
DB00563MethotrexateSolute carrier organic anion transporter family member 1B1transporter
DB00563Methotrexate6-phosphogluconate dehydrogenase, decarboxylatingenzyme
DB00563MethotrexateProton-coupled folate transportertransporter
DB00563MethotrexateFolylpolyglutamate synthase, mitochondrialenzyme
DB00563MethotrexateGamma-glutamyl hydrolaseenzyme
DB00563MethotrexateDihydrofolate reductaseenzyme
DB00563MethotrexateThymidylate synthaseenzyme
DB00563MethotrexateBifunctional purine biosynthesis protein PURHenzyme
DB00563MethotrexateSolute carrier organic anion transporter family member 4C1transporter
DB00563MethotrexateFolate transporter 1transporter
DB00563MethotrexateFolate receptor alphatransporter
DB00563MethotrexateCytochrome P450 3A4enzyme
DB00563MethotrexateThymidylate synthasetarget
DB00563MethotrexateBifunctional purine biosynthesis protein PURHtarget
DB00563MethotrexateFolate receptor betatransporter
DB00563MethotrexateSolute carrier family 15 member 1transporter
DB00563MethotrexateProton-coupled amino acid transporter 1transporter
DB00563MethotrexateCarboxypeptidase G2enzyme
DrugDrug NamePhaseStatusCount
DB08898Glucarpidase0Recruiting1
DB00650Leucovorin0Recruiting1
DB00563Methotrexate0Recruiting1
DB00073Rituximab0Recruiting1
DB13915Axicabtagene ciloleucel1Active Not Recruiting1
DB00531Cyclophosphamide1Active Not Recruiting1
DB00531Cyclophosphamide1Recruiting1
DB01234Dexamethasone1Completed1
DB01073Fludarabine1Active Not Recruiting1
DB01073Fludarabine1Recruiting1
DB00563Methotrexate1Completed1
DB00642Pemetrexed1Completed1
DB08910Pomalidomide1Completed1
DB00073Rituximab1Completed1
DB11703Acalabrutinib1 / 2Recruiting1
DB00958Carboplatin1 / 2Active Not Recruiting1
DB14844Dordaviprone1 / 2Terminated1
DB08898Glucarpidase1 / 2Recruiting1
DB00480Lenalidomide1 / 2Recruiting1
DB00742Mannitol1 / 2Active Not Recruiting1
DB16620Methopterin1 / 2Active Not Recruiting1
DB00563Methotrexate1 / 2Active Not Recruiting1
DB00563Methotrexate1 / 2Recruiting2
DB00073Rituximab1 / 2Active Not Recruiting1
DB00073Rituximab1 / 2Recruiting1
DB11942Selinexor1 / 2Recruiting1
DB15044Tafasitamab1 / 2Recruiting1
DB09499Thiosulfuric acid1 / 2Active Not Recruiting1
DB11703Acalabrutinib2Recruiting1
DB00262Carmustine2Completed1
DB00987Cytarabine2Active Not Recruiting1
DB00987Cytarabine2Completed1
DB01262Decitabine2Recruiting1
DB09053Ibrutinib2Active Not Recruiting1
DB09053Ibrutinib2Recruiting1
DB15244Iopofosine I-1312Recruiting1
DB11633Isavuconazole2Active Not Recruiting1
DB11633Isavuconazole2Recruiting1
DB06636Isavuconazonium2Recruiting1
DB00480Lenalidomide2Recruiting2
DB00563Methotrexate2Active Not Recruiting1
DB00563Methotrexate2Completed2
DB00563Methotrexate2Not Yet Recruiting1
DB16272Orelabrutinib2Recruiting2
DB00642Pemetrexed2Recruiting1
DB00073Rituximab2Completed1
DB00073Rituximab2Not Yet Recruiting1
DB00073Rituximab2Recruiting2
DB04572Thiotepa2Completed1
DB06334Tucidinostat2Not Yet Recruiting1
DB15035Zanubrutinib2Recruiting1
DB00563Methotrexate3Recruiting1
DB00563Methotrexate4Completed1
DB06215FerumoxytolNot AvailableCompleted1
DB12091GadoliniumNot AvailableCompleted1
DB15035ZanubrutinibNot AvailableRecruiting1