Peptic Ulcers

Also known as: Peptic ulcer / Gastroduodenal ulcer / Ulcer gastroduodenal / Peptic ulcer, site unspecified / Peptic ulcer NOS / Peptic ulcer syndrome / Ulcer syndrome peptic / Peptic ulcer disease / Syndrome peptic ulcer / PUD / Peptic ulceration / GDU / Ulcer peptic

DrugDrug NameDrug Description
DB00572AtropineAn alkaloid, originally from Atropa belladonna, but found in other plants, mainly solanaceae.
DB00986GlycopyrroniumGlycopyrronium (as the bromide salt glycopyrrolate) is a synthetic anticholinergic agent with a quaternary ammonium structure. A muscarinic competitive antagonist used as an antispasmodic, in some disorders of the gastrointestinal tract, and to reduce salivation with some anesthetics. In October 2015, glycopyrrolate was approved by the FDA for use as a standalone treatment for Chronic obstructive pulmonary disease (COPD), as Seebri Neohaler.
DB00424HyoscyamineHyoscyamine is a chemical compound, a tropane alkaloid it is the levo-isomer to atropine. It is a secondary metabolite of some plants, particularly henbane (Hyoscamus niger.) Hyoscyamine is used to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in end of life care.
DB08938MagaldrateMagaldrate is an antacid drug used for the treatment of esophagitis, duodenal and gastric ulcers, and gastroesophageal reflux. Magaldrate has been discontinued in the US market.
DB04843MepenzolateMepenzolate is a post-ganglionic parasympathetic inhibitor. It decreases gastric acid and pepsin secretion and suppresses spontaneous contractions of the colon. Mepenzolate diminishes gastric acid and pepsin secretion. Mepenzolate also suppresses spontaneous contractions of the colon. Pharmacologically, it is a post-ganglionic parasympathetic inhibitor. It has not been shown to be effective in contributing to the healing of peptic ulcer, decreasing the rate of recurrence, or preventing complications.
DB00462Methscopolamine bromideA muscarinic antagonist used to study binding characteristics of muscarinic cholinergic receptors.
DB00782PropanthelineA muscarinic antagonist used as an antispasmodic, in rhinitis, in urinary incontinence, and in the treatment of ulcers. At high doses it has nicotinic effects resulting in neuromuscular blocking.
DrugDrug NamePhaseStatusCount
DB13135AGN-2019041Completed1
DB00736Esomeprazole1Completed1
DB12770Lafutidine1Completed1
DB00758Clopidogrel2Completed1
DB00736Esomeprazole2Completed1
DB00945Acetylsalicylic acid3Completed1
DB00482Celecoxib3Completed1
DB00736Esomeprazole3Completed1
DB05369HZT-5013Completed1
DB01050Ibuprofen3Completed1
DB11964Ilaprazole3Completed1
DB00448Lansoprazole3Completed1
DB00448Lansoprazole3Recruiting1
DB00448Lansoprazole3Unknown Status1
DB00788Naproxen3Completed1
DB00338Omeprazole3Completed1
DB00213Pantoprazole3Completed3
DB00213Pantoprazole3Unknown Status2
DB11739Vonoprazan3Recruiting1
DB00945Acetylsalicylic acid4Completed2
DB01060Amoxicillin4Completed6
DB00207Azithromycin4Completed1
DB00626Bacitracin4Completed2
DB04115Berberine4Completed2
DB01294Bismuth Subsalicylate4Completed5
DB00482Celecoxib4Completed1
DB01211Clarithromycin4Completed6
DB00736Esomeprazole4Completed2
DB00736Esomeprazole4Unknown Status1
DB00736Esomeprazole4Withdrawn1
DB00927Famotidine4Active Not Recruiting1
DB11964Ilaprazole4Completed1
DB00448Lansoprazole4Active Not Recruiting1
DB00448Lansoprazole4Completed3
DB01137Levofloxacin4Completed1
DB00916Metronidazole4Completed2
DB00788Naproxen4Completed1
DB00994Neomycin4Completed2
DB00338Omeprazole4Completed2
DB00338Omeprazole4Withdrawn1
DB00213Pantoprazole4Withdrawn1
DB00781Polymyxin B sulfate4Completed2
DB09345Pramocaine4Completed2
DB00863Ranitidine4Withdrawn1
DB06723Aluminum hydroxideNot AvailableUnknown Status1
DB00668EpinephrineNot AvailableCompleted1
DB00927FamotidineNot AvailableRecruiting2
DB00448LansoprazoleNot AvailableUnknown Status1
DB00213PantoprazoleNot AvailableRecruiting1
DB00213PantoprazoleNot AvailableUnknown Status1