Chronic Lymphocytic Leukemia (CLL) - Refractory

Also known as: Chronic lymphocytic leukemia refractory / Chronic, refractory Lymphocytic Leukemia / Refractory CLL / CLL, Refractory / Chronic Lymphocytic Leukaemia Refractory / Chronic, refractory Lymphocytic leukaemia / Refractory Chronic Lymphocytic Leukemia

DrugDrug NameDrug Description
DB00480LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
DB06650OfatumumabA CD20 inhibitor used for the treatment of patients with chronic lymphocytic leukemia (CLL) refractory to fludarabine and alemtuzumab.
DB00526OxaliplatinA platinum based chemotherapy agent used to treat carcinoma of the colon or rectum or stage III colon cancer.
DrugDrug NamePhaseStatusCount
DB00531Cyclophosphamide0Recruiting1
DB00091Cyclosporine0Recruiting1
DB01073Fludarabine0Recruiting1
DB00688Mycophenolate mofetil0Recruiting1
DB025942'-Deoxycytidine1Completed1
DB12707AR-421Completed1
DB00041Aldesleukin1Completed1
DB00087Alemtuzumab1Terminated1
DB05220Alisertib1Completed1
DB12442Alvespimycin1Terminated1
DB03496Alvocidib1Completed2
DB03496Alvocidib1Terminated1
DB06467Apolizumab1Completed1
DB06769Bendamustine1Completed1
DB06769Bendamustine1Recruiting1
DB06769Bendamustine1Terminated2
DB02379Beta-D-Glucose1Recruiting1
DB00188Bortezomib1Completed2
DB00188Bortezomib1Terminated1
DB11752Bryostatin 11Completed1
DB11666Buparlisib1Terminated1
DB12109CPI-6131Terminated1
DB08889Carfilzomib1Completed1
DB00531Cyclophosphamide1Completed2
DB00531Cyclophosphamide1Not Yet Recruiting1
DB00531Cyclophosphamide1Recruiting3
DB00531Cyclophosphamide1Terminated1
DB00091Cyclosporine1Completed1
DB01254Dasatinib1Completed1
DB01262Decitabine1Completed1
DB00380Dexrazoxane1Terminated1
DB00997Doxorubicin1Terminated1
DB00773Etoposide1Recruiting1
DB00773Etoposide1Terminated1
DB01590Everolimus1Completed1
DB01073Fludarabine1Completed4
DB01073Fludarabine1Not Yet Recruiting1
DB01073Fludarabine1Recruiting3
DB01073Fludarabine1Terminated1
DB14865Human interleukin-21Completed1
DB09053Ibrutinib1Active Not Recruiting2
DB09053Ibrutinib1Recruiting2
DB09053Ibrutinib1Terminated2
DB09054Idelalisib1Not Yet Recruiting1
DB00619Imatinib1Completed1
DB06186Ipilimumab1Completed1
DB00160L-Alanine1Recruiting1
DB00480Lenalidomide1Active Not Recruiting2
DB00480Lenalidomide1Completed2
DB00480Lenalidomide1Recruiting1
DB00166Lipoic acid1Terminated1
DB00888Mechlorethamine1Recruiting1
DB01042Melphalan1Recruiting1
DB00331Metformin1Active Not Recruiting1
DB06328Methoxyamine1Completed1
DB00688Mycophenolate mofetil1Completed1
DB00688Mycophenolate mofetil1Recruiting1
DB12191Obatoclax1Terminated2
DB06650Ofatumumab1Terminated1
DB00526Oxaliplatin1Terminated1
DB11759Pevonedistat1Recruiting1
DB00503Ritonavir1Active Not Recruiting1
DB00073Rituximab1Active Not Recruiting1
DB00073Rituximab1Completed3
DB00073Rituximab1Not Yet Recruiting1
DB00073Rituximab1Recruiting1
DB00073Rituximab1Terminated4
DB06176Romidepsin1Active Not Recruiting1
DB06176Romidepsin1Completed1
DB11965SJG-1361Terminated1
DB11942Selinexor1Recruiting1
DB00877Sirolimus1Completed1
DB00398Sorafenib1Completed1
DB14546Sulfate ion1Completed1
DB01268Sunitinib1Completed1
DB00864Tacrolimus1Recruiting1
DB06398Tanespimycin1Terminated2
DB13881Tisagenlecleucel1Completed1
DB06273Tocilizumab1Recruiting1
DB05109Trabectedin1Recruiting1
DB00313Valproic acid1Completed1
DB11581Venetoclax1Not Yet Recruiting1
DB11581Venetoclax1Recruiting1
DB00541Vincristine1Completed1
DB00541Vincristine1Terminated1
DB02546Vorinostat1Completed1
DB00087Alemtuzumab1 / 2Active Not Recruiting1
DB03496Alvocidib1 / 2Completed1
DB06769Bendamustine1 / 2Completed2
DB02379Beta-D-Glucose1 / 2Active Not Recruiting2
DB00262Carmustine1 / 2Active Not Recruiting2
DB00531Cyclophosphamide1 / 2Active Not Recruiting2
DB00531Cyclophosphamide1 / 2Not Yet Recruiting1
DB00531Cyclophosphamide1 / 2Recruiting1
DB00091Cyclosporine1 / 2Active Not Recruiting4
DB00987Cytarabine1 / 2Active Not Recruiting2
DB12021Dinaciclib1 / 2Completed1
DB12121Entospletinib1 / 2Recruiting1
DB00773Etoposide1 / 2Active Not Recruiting2
DB01590Everolimus1 / 2Active Not Recruiting1
DB05076Fenretinide1 / 2Terminated1
DB01073Fludarabine1 / 2Active Not Recruiting5
DB01073Fludarabine1 / 2Not Yet Recruiting1
DB01073Fludarabine1 / 2Recruiting1
DB09053Ibrutinib1 / 2Active Not Recruiting1
DB00160L-Alanine1 / 2Active Not Recruiting2
DB00888Mechlorethamine1 / 2Active Not Recruiting2
DB01042Melphalan1 / 2Active Not Recruiting2
DB00688Mycophenolate mofetil1 / 2Active Not Recruiting5
DB08935Obinutuzumab1 / 2Active Not Recruiting1
DB08935Obinutuzumab1 / 2Recruiting1
DB06650Ofatumumab1 / 2Completed1
DB06603Panobinostat1 / 2Active Not Recruiting1
DB00073Rituximab1 / 2Active Not Recruiting1
DB00073Rituximab1 / 2Completed2
DB00073Rituximab1 / 2Terminated1
DB00877Sirolimus1 / 2Active Not Recruiting1
DB00864Tacrolimus1 / 2Active Not Recruiting1
DB13881Tisagenlecleucel1 / 2Recruiting1
DB07232Veliparib1 / 2Completed1
DB11581Venetoclax1 / 2Active Not Recruiting1
DB00087Alemtuzumab2Active Not Recruiting2
DB03496Alvocidib2Completed1
DB03496Alvocidib2Terminated1
DB09312Antilymphocyte immunoglobulin (horse)2Completed1
DB09312Antilymphocyte immunoglobulin (horse)2Terminated1
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)2Terminated1
DB06467Apolizumab2Completed1
DB11595Atezolizumab2Recruiting1
DB01076Atorvastatin2Active Not Recruiting1
DB00394Beclomethasone dipropionate2Completed1
DB02379Beta-D-Glucose2Completed1
DB00112Bevacizumab2Completed1
DB00112Bevacizumab2Withdrawn1
DB00188Bortezomib2Completed1
DB01008Busulfan2Completed1
DB01008Busulfan2Terminated1
DB00262Carmustine2Completed1
DB04849Cediranib2Completed1
DB00531Cyclophosphamide2Active Not Recruiting1
DB00531Cyclophosphamide2Completed4
DB00531Cyclophosphamide2Terminated1
DB00531Cyclophosphamide2Withdrawn1
DB00091Cyclosporine2Active Not Recruiting4
DB00091Cyclosporine2Completed5
DB00987Cytarabine2Completed1
DB01254Dasatinib2Completed1
DB01609Deferasirox2Terminated1
DB01234Dexamethasone2Completed1
DB11952Duvelisib2Recruiting1
DB00773Etoposide2Completed1
DB01073Fludarabine2Active Not Recruiting5
DB01073Fludarabine2Completed7
DB01073Fludarabine2Terminated2
DB01073Fludarabine2Withdrawn2
DB09053Ibrutinib2Active Not Recruiting4
DB09053Ibrutinib2Recruiting1
DB09054Idelalisib2Recruiting1
DB00160L-Alanine2Completed1
DB00480Lenalidomide2Active Not Recruiting2
DB00480Lenalidomide2Terminated1
DB00888Mechlorethamine2Completed1
DB01042Melphalan2Completed2
DB00563Methotrexate2Completed3
DB00959Methylprednisolone2Completed1
DB14644Methylprednisolone hemisuccinate2Completed1
DB00688Mycophenolate mofetil2Active Not Recruiting5
DB00688Mycophenolate mofetil2Completed8
DB00688Mycophenolate mofetil2Terminated1
DB00688Mycophenolate mofetil2Withdrawn1
DB09035Nivolumab2Active Not Recruiting1
DB08935Obinutuzumab2Active Not Recruiting1
DB08935Obinutuzumab2Recruiting1
DB00904Ondansetron2Completed1
DB09037Pembrolizumab2Recruiting1
DB00073Rituximab2Completed3
DB00073Rituximab2Terminated2
DB00073Rituximab2Withdrawn1
DB00877Sirolimus2Completed2
DB00398Sorafenib2Terminated1
DB12369Sotrastaurin2Withdrawn1
DB01268Sunitinib2Completed1
DB01268Sunitinib2Terminated1
DB00864Tacrolimus2Active Not Recruiting1
DB00864Tacrolimus2Completed6
DB00864Tacrolimus2Terminated1
DB00864Tacrolimus2Withdrawn1
DB15044Tafasitamab2Active Not Recruiting1
DB06287Temsirolimus2Completed1
DB06287Temsirolimus2Terminated1
DB01041Thalidomide2Completed1
DB01041Thalidomide2Terminated1
DB11581Venetoclax2Active Not Recruiting2
DB11581Venetoclax2Recruiting1
DB02546Vorinostat2Completed1
DB00091Cyclosporine3Active Not Recruiting1
DB00091Cyclosporine3Completed1
DB01073Fludarabine3Active Not Recruiting1
DB01073Fludarabine3Completed1
DB00688Mycophenolate mofetil3Active Not Recruiting1
DB00688Mycophenolate mofetil3Completed1
DB00877Sirolimus3Completed1
DB09312Antilymphocyte immunoglobulin (horse)Not AvailableActive Not Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableActive Not Recruiting1
DB01169Arsenic trioxideNot AvailableTerminated1
DB04456Arsenous acidNot AvailableTerminated1
DB01008BusulfanNot AvailableCompleted1
DB00958CarboplatinNot AvailableCompleted1
DB00262CarmustineNot AvailableCompleted1
DB00531CyclophosphamideNot AvailableCompleted1
DB00091CyclosporineNot AvailableActive Not Recruiting2
DB00091CyclosporineNot AvailableCompleted1
DB00773EtoposideNot AvailableCompleted1
DB00773EtoposideNot AvailableTerminated1
DB00099FilgrastimNot AvailableTerminated2
DB01073FludarabineNot AvailableActive Not Recruiting2
DB01073FludarabineNot AvailableCompleted1
DB00529FoscarnetNot AvailableCompleted1
DB01004GanciclovirNot AvailableCompleted1
DB14509Lithium carbonateNot AvailableCompleted1
DB01042MelphalanNot AvailableActive Not Recruiting1
DB01042MelphalanNot AvailableCompleted1
DB00688Mycophenolate mofetilNot AvailableActive Not Recruiting2
DB00688Mycophenolate mofetilNot AvailableCompleted1
DB00039PaliferminNot AvailableCompleted1
DB06809PlerixaforNot AvailableTerminated2
DB04572ThiotepaNot AvailableCompleted1
DB01610ValganciclovirNot AvailableCompleted1