Acute Uncomplicated Pyelonephritis

Also known as: Acute, uncomplicated Pyelonephritis

Drug	Drug Name	Drug Description
DB00537	Ciprofloxacin	A second generation fluoroquinolone used to treat various susceptible bacterial infections.
DB00766	Clavulanic acid	A beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.

Drug	Drug Name	Target	Type
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 2-alpha	target
DB00537	Ciprofloxacin	Cytochrome P450 1A2	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A4	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A5	enzyme
DB00537	Ciprofloxacin	Cytochrome P450 3A7	enzyme
DB00537	Ciprofloxacin	P-glycoprotein 1	transporter
DB00537	Ciprofloxacin	Potassium voltage-gated channel subfamily H member 2	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit A	target
DB00537	Ciprofloxacin	DNA topoisomerase 4 subunit B	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	Multidrug resistance protein MdtK	target
DB00537	Ciprofloxacin	Gyrase A	target
DB00537	Ciprofloxacin	DNA gyrase subunit A	target
DB00537	Ciprofloxacin	Multidrug and toxin extrusion protein 1	transporter
DB00537	Ciprofloxacin	Multidrug and toxin extrusion protein 2	transporter
DB00537	Ciprofloxacin	Serum albumin	carrier
DB00766	Clavulanic acid	Bacterial beta-lactamase enzymes	target
DB00766	Clavulanic acid	Sodium/glucose cotransporter 1	transporter

Drug	Drug Name	Phase	Status	Count
DB01212	Ceftriaxone	4	Completed	1
DB01137	Levofloxacin	4	Terminated	1