Obsessive Compulsive Disorder (OCD)

Also known as: Obsessive-Compulsive Disorder (OCD) / Obsessive Compulsive Disorder / Obsessive-Compulsive Disorder / Obsessive Compulsive Disorders / Obsessive-compulsive disorders / OCD / [X]Obsessive-compulsive disorder, unspecified / Obsessive-compulsive reaction / Reaction obsessive-compulsive / Obsessive-compulsive neurosis / Anancastic neurosis

DrugDrug NameDrug Description
DB00215CitalopramA selective serotonin reuptake inhibitor (SSRI) used in the treatment of depression.
DB01242ClomipramineA tricyclic antidepressant used in the treatment of obsessive-compulsive disorder and disorders with an obsessive-compulsive component, such as depression, schizophrenia, and Tourette’s disorder.
DB01175EscitalopramA selective serotonin re-uptake inhibitor used in the treatment of major depressive disorder (MDD), generalized anxiety disorder (GAD), and other select psychiatric disorders such as obsessive-compulsive disorder (OCD).
DB00472FluoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, bulimia, OCD, premenstrual dysphoric disorder, panic disorder, and bipolar I.
DB00176FluvoxamineA selective serotonin-reuptake inhibitor used to treat obsessive-compulsive disorder.
DB00502HaloperidolAn antipsychotic agent used to treat schizophrenia and other psychoses, as well as symptoms of agitation, irritability, and delirium.
DB00370MirtazapineA tetracyclic antidepressant used in the treatment of major depression and is used off-label as a drug for insomnia and to increase appetite.
DB00715ParoxetineA selective serotonin reuptake inhibitor used to treat major depressive disorder, panic disorder, OCD, social phobia, generalized anxiety disorder, the vasomotor symptoms of menopause, and premenstrual dysphoric disorder.
DB01104SertralineA selective serotonin reuptake inhibitor (SSRI) indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions.
DB01323St. John's WortAn herbal ingredient used in non-prescription therapeutic products for the short-term treatment of minor skin irritations, insomnia, depression, and anxiety.
DrugDrug NameTargetType
DB00215CitalopramSodium-dependent serotonin transportertarget
DB00215CitalopramCytochrome P450 2C19enzyme
DB00215CitalopramCytochrome P450 2D6enzyme
DB00215CitalopramCytochrome P450 3A4enzyme
DB00215CitalopramP-glycoprotein 1transporter
DB00215CitalopramCytochrome P450 1A2enzyme
DB00215CitalopramHistamine H1 receptortarget
DB01242ClomipramineSodium-dependent serotonin transportertarget
DB01242ClomipramineSodium-dependent noradrenaline transportertarget
DB01242ClomipramineGlutathione S-transferase Ptarget
DB01242Clomipramine5-hydroxytryptamine receptor 2Atarget
DB01242ClomipramineCytochrome P450 1A2enzyme
DB01242ClomipramineCytochrome P450 2D6enzyme
DB01242ClomipramineCytochrome P450 2C19enzyme
DB01242ClomipramineP-glycoprotein 1transporter
DB01242ClomipramineCytochrome P450 3A4enzyme
DB01242Clomipramine5-hydroxytryptamine receptor 2Btarget
DB01242Clomipramine5-hydroxytryptamine receptor 2Ctarget
DB01242ClomipramineSerum albumincarrier
DB01175EscitalopramSodium-dependent serotonin transportertarget
DB01175EscitalopramCytochrome P450 3A4enzyme
DB01175EscitalopramCytochrome P450 2D6enzyme
DB01175EscitalopramSodium-dependent dopamine transportertarget
DB01175EscitalopramSodium-dependent noradrenaline transportertarget
DB01175EscitalopramMuscarinic acetylcholine receptor M1target
DB01175EscitalopramHistamine H1 receptortarget
DB01175EscitalopramCytochrome P450 2C19enzyme
DB01175EscitalopramMonoamine oxidaseenzyme
DB01175EscitalopramP-glycoprotein 1transporter
DB01175Escitalopram5-hydroxytryptamine receptor 1Atarget
DB01175Escitalopram5-hydroxytryptamine receptor 2Atarget
DB01175Escitalopram5-hydroxytryptamine receptor 2Ctarget
DB01175EscitalopramAlpha-1 adrenergic receptorstarget
DB01175EscitalopramAlpha-2 adrenergic receptorstarget
DB01175EscitalopramDopamine D2 receptortarget
DB00472FluoxetineSodium-dependent serotonin transportertarget
DB00472FluoxetineCytochrome P450 2C9enzyme
DB00472FluoxetineCytochrome P450 2D6enzyme
DB00472FluoxetineCYP2B proteinenzyme
DB00472FluoxetineCytochrome P450 1A2enzyme
DB00472FluoxetineCytochrome P450 3A4enzyme
DB00472FluoxetineCytochrome P450 2C19enzyme
DB00472FluoxetineP-glycoprotein 1transporter
DB00472FluoxetineCytochrome P450 2B6enzyme
DB00472FluoxetineCytochrome P450 3A5enzyme
DB00472FluoxetineSerum albumincarrier
DB00472FluoxetineAlpha-1-acid glycoprotein 1carrier
DB00472FluoxetinePotassium voltage-gated channel subfamily H member 2target
DB00472Fluoxetine5-hydroxytryptamine receptor 2Ctarget
DB00472FluoxetineCyclin-dependent kinases regulatory subunit 1target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-2target
DB00472FluoxetineNeuronal acetylcholine receptor subunit alpha-3target
DB00472FluoxetineNeuronal acetylcholine receptor subunit beta-4target
DB00176FluvoxamineSodium-dependent serotonin transportertarget
DB00176FluvoxamineCytochrome P450 1A2enzyme
DB00176FluvoxamineCytochrome P450 2D6enzyme
DB00176FluvoxamineCytochrome P450 2C9enzyme
DB00176FluvoxamineCytochrome P450 2C19enzyme
DB00176FluvoxamineCytochrome P450 1A1enzyme
DB00176FluvoxamineCytochrome P450 3A4enzyme
DB00176FluvoxamineCytochrome P450 3A Subfamilyenzyme
DB00176FluvoxamineP-glycoprotein 1transporter
DB00176FluvoxamineCytochrome P450 2B6enzyme
DB00176FluvoxaminePotassium voltage-gated channel subfamily H member 2target
DB00176FluvoxamineBile salt export pumptransporter
DB00502HaloperidolDopamine D2 receptortarget
DB00502HaloperidolGlutamate receptor ionotropic, NMDA 2Btarget
DB00502HaloperidolDopamine D1 receptortarget
DB00502HaloperidolCytochrome P450 1A2enzyme
DB00502HaloperidolCytochrome P450 2D6enzyme
DB00502Haloperidol5-hydroxytryptamine receptor 2Atarget
DB00502HaloperidolDopamine D3 receptortarget
DB00502HaloperidolCytochrome P450 3A4enzyme
DB00502HaloperidolCytochrome P450 3A5enzyme
DB00502HaloperidolCytochrome P450 3A7enzyme
DB00502HaloperidolP-glycoprotein 1transporter
DB00502HaloperidolCarbonyl reductase [NADPH] 1enzyme
DB00502HaloperidolUDP-glucuronosyltransferase 1-9enzyme
DB00502HaloperidolCytochrome P450 2C19enzyme
DB00502HaloperidolCytochrome P450 2C9enzyme
DB00502HaloperidolMelanin-concentrating hormone receptor 1target
DB00502HaloperidolSynaptic vesicular amine transportertarget
DB00502Haloperidol5-hydroxytryptamine receptor 2Ctarget
DB00502HaloperidolSigma non-opioid intracellular receptor 1target
DB00502HaloperidolHistamine H1 receptortarget
DB00502HaloperidolMuscarinic acetylcholine receptor M3target
DB00502HaloperidolAlpha-1A adrenergic receptortarget
DB00502HaloperidolAlpha-2A adrenergic receptortarget
DB00502HaloperidolAlpha-2B adrenergic receptortarget
DB00502HaloperidolAlpha-2C adrenergic receptortarget
DB00502Haloperidol5-hydroxytryptamine receptor 1Atarget
DB00502Haloperidol5-hydroxytryptamine receptor 6target
DB00502Haloperidol5-hydroxytryptamine receptor 7target
DB00502HaloperidolCytochrome P450 1A1enzyme
DB00370Mirtazapine5-hydroxytryptamine receptor 2Atarget
DB00370Mirtazapine5HT3 serotonin receptortarget
DB00370MirtazapineAlpha-2A adrenergic receptortarget
DB00370Mirtazapine5-hydroxytryptamine receptor 2Ctarget
DB00370MirtazapineKappa-type opioid receptortarget
DB00370MirtazapineHistamine H1 receptortarget
DB00370MirtazapineCytochrome P450 1A2enzyme
DB00370MirtazapineCytochrome P450 3A4enzyme
DB00370MirtazapineCytochrome P450 2D6enzyme
DB00370MirtazapineAlpha-1 adrenergic receptorstarget
DB00370MirtazapineSodium-dependent serotonin transportertransporter
DB00715ParoxetineSodium-dependent serotonin transportertarget
DB00715ParoxetineSodium-dependent noradrenaline transportertarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Atarget
DB00715ParoxetineCytochrome P450 2D6enzyme
DB00715ParoxetineCytochrome P450 2C9enzyme
DB00715ParoxetineP-glycoprotein 1transporter
DB00715ParoxetineCytochrome P450 2B6enzyme
DB00715ParoxetineCytochrome P450 1A2enzyme
DB00715ParoxetineCytochrome P450 3A4enzyme
DB00715ParoxetineAlpha-1 adrenergic receptorstarget
DB00715ParoxetineAlpha-2 adrenergic receptorstarget
DB00715ParoxetineBeta adrenergic receptortarget
DB00715ParoxetineDopamine D2 receptortarget
DB00715ParoxetineHistamine H1 receptortarget
DB00715ParoxetineSerotonin Receptorstarget
DB00715ParoxetineMuscarinic acetylcholine receptortarget
DB00715Paroxetine5-hydroxytryptamine receptor 2Btarget
DB00715ParoxetineD(1) dopamine receptortarget
DB00715ParoxetineCytochrome P450 2C19enzyme
DB01104SertralineSodium-dependent serotonin transportertarget
DB01104SertralineCytochrome P450 2B6enzyme
DB01104SertralineCytochrome P450 2C19enzyme
DB01104SertralineCytochrome P450 2C9enzyme
DB01104SertralineCytochrome P450 2D6enzyme
DB01104SertralineSodium-dependent dopamine transportertarget
DB01104SertralineCYP2B proteinenzyme
DB01104SertralineCytochrome P450 3A4enzyme
DB01104SertralineAmine oxidase [flavin-containing] Benzyme
DB01104SertralineAmine oxidase [flavin-containing] Aenzyme
DB01104SertralineP-glycoprotein 1transporter
DB01104SertralineSerum albumincarrier
DB01104SertralineSigma receptortarget
DB01323St. John's WortP-glycoprotein 1transporter
DB01323St. John's WortCytochrome P450 3A4enzyme
DB01323St. John's WortCytochrome P450 2D6enzyme
DB01323St. John's WortCytochrome P450 2C19enzyme
DrugDrug NamePhaseStatusCount
DB06288Amisulpride1Completed1
DB00472Fluoxetine1Recruiting1
DB00186Lorazepam1Recruiting1
DB00627Niacin1Recruiting1
DB00715Paroxetine1Completed1
DB00413Pramipexole1Completed1
DB11664Psilocybine1Recruiting2
DB00073Rituximab1Recruiting1
DB01221Ketamine1 / 2Completed1
DB01221Ketamine1 / 2Terminated1
DB14009Medical Cannabis1 / 2Completed1
DB00683Midazolam1 / 2Terminated1
DB00486Nabilone1 / 2Completed1
DB01104Sertraline1 / 2Completed1
DB06151Acetylcysteine2Completed2
DB06151Acetylcysteine2Terminated1
DB06594Agomelatine2Completed1
DB00207Azithromycin2Completed1
DB12426Bitopertin2Completed1
DB01242Clomipramine2Unknown Status1
DB00260Cycloserine2Completed1
DB00260Cycloserine2Unknown Status1
DB00260Cycloserine2Withdrawn1
DB00470Dronabinol2Completed1
DB01175Escitalopram2Completed1
DB01205Flumazenil2Terminated1
DB00472Fluoxetine2Terminated1
DB00145Glycine2Completed1
DB01221Ketamine2Active Not Recruiting1
DB01221Ketamine2Completed3
DB01221Ketamine2Recruiting1
DB01221Ketamine2Terminated1
DB00555Lamotrigine2Completed1
DB01043Memantine2Completed1
DB00683Midazolam2Active Not Recruiting1
DB00683Midazolam2Recruiting1
DB01017Minocycline2Completed1
DB01017Minocycline2Terminated1
DB00704Naltrexone2Terminated1
DB09152Nitrogen2Not Yet Recruiting1
DB06690Nitrous oxide2Not Yet Recruiting1
DB00904Ondansetron2Terminated1
DB00107Oxytocin2Completed1
DB01267Paliperidone2Completed1
DB01224Quetiapine2Completed1
DB11801Rapastinel2Completed1
DB00740Riluzole2Completed2
DB12519Sarcosine2Completed1
DB06369Secretin human2Completed1
DB01323St. John's Wort2Completed1
DB13453Xenon2Withdrawn1
DB01202Levetiracetam2 / 3Terminated1
DB01104Sertraline2 / 3Terminated1
DB00323Tolcapone2 / 3Recruiting1
DB00215Citalopram3Completed1
DB01242Clomipramine3Completed2
DB00260Cycloserine3Completed2
DB01175Escitalopram3Completed2
DB00472Fluoxetine3Completed1
DB00176Fluvoxamine3Completed3
DB01043Memantine3Completed1
DB00715Paroxetine3Completed1
DB01224Quetiapine3Completed1
DB08839Serotonin3Completed1
DB01104Sertraline3Completed2
DB00273Topiramate3Completed1
DB00285Venlafaxine3Completed1
DB01060Amoxicillin4Completed1
DB00215Citalopram4Completed1
DB00215Citalopram4Recruiting1
DB01242Clomipramine4Completed2
DB00260Cycloserine4Active Not Recruiting1
DB00260Cycloserine4Completed1
DB00476Duloxetine4Completed1
DB01175Escitalopram4Completed2
DB01175Escitalopram4Unknown Status2
DB00472Fluoxetine4Completed3
DB00472Fluoxetine4Recruiting1
DB00176Fluvoxamine4Completed1
DB00176Fluvoxamine4Recruiting1
DB00176Fluvoxamine4Terminated1
DB00176Fluvoxamine4Unknown Status1
DB00422Methylphenidate4Completed1
DB00788Naproxen4Not Yet Recruiting1
DB00368Norepinephrine4Completed1
DB00334Olanzapine4Completed1
DB00904Ondansetron4Completed2
DB00904Ondansetron4Recruiting1
DB00715Paroxetine4Completed1
DB00715Paroxetine4Recruiting1
DB00230Pregabalin4Completed1
DB00571Propranolol4Suspended1
DB01224Quetiapine4Completed3
DB08839Serotonin4Completed1
DB08839Serotonin4Recruiting1
DB01104Sertraline4Completed1
DB01104Sertraline4Recruiting2
DB01104Sertraline4Terminated1
DB00273Topiramate4Recruiting1
DB00273Topiramate4Unknown Status1
DB00182AmphetamineNot AvailableCompleted1
DB01238AripiprazoleNot AvailableCompleted1
DB01238AripiprazoleNot AvailableWithdrawn1
DB00201CaffeineNot AvailableCompleted1
DB00215CitalopramNot AvailableRecruiting1
DB01242ClomipramineNot AvailableCompleted1
DB00260CycloserineNot AvailableCompleted3
DB00476DuloxetineNot AvailableActive Not Recruiting1
DB00476DuloxetineNot AvailableCompleted1
DB00476DuloxetineNot AvailableWithdrawn1
DB01175EscitalopramNot AvailableCompleted1
DB01175EscitalopramNot AvailableRecruiting1
DB00472FluoxetineNot AvailableActive Not Recruiting1
DB00472FluoxetineNot AvailableCompleted1
DB00472FluoxetineNot AvailableNot Yet Recruiting1
DB00472FluoxetineNot AvailableRecruiting2
DB00176FluvoxamineNot AvailableRecruiting3
DB00145GlycineNot AvailableCompleted1
DB01043MemantineNot AvailableCompleted1
DB00704NaltrexoneNot AvailableCompleted1
DB00715ParoxetineNot AvailableActive Not Recruiting1
DB00715ParoxetineNot AvailableRecruiting2
DB00734RisperidoneNot AvailableCompleted1
DB08839SerotoninNot AvailableCompleted1
DB01104SertralineNot AvailableActive Not Recruiting1
DB01104SertralineNot AvailableRecruiting3
DB00285VenlafaxineNot AvailableActive Not Recruiting1
DB00246ZiprasidoneNot AvailableCompleted1