Nephritis, Lupus

Also known as: Lupus Nephritis / Nephritis SLE / Nephritis systemic lupus erythematosus / SLE nephritis

DrugDrug NameDrug Description
DB00993AzathioprineAn immunosuppressant used to prevent renal transplant rejection, treat rheumatoid arthritis, Crohn's disease, and ulcerative colitis.
DB00531CyclophosphamideA nitrogen mustard used to treat lymphomas, myelomas, leukemia, mycosis fungoides, neuroblastoma, ovarian adenocarcinoma, retinoblastoma, and breast carcinoma.
DB00091CyclosporineA steroid-sparing immunosuppressant used in organ and bone marrow transplants as well as inflammatory conditions such as ulcerative colitis, rheumatoid arthritis, and atopic dermatitis.
DrugDrug NameTargetType
DB00993AzathioprineHypoxanthine-guanine phosphoribosyltransferasetarget
DB00993AzathioprineThiopurine S-methyltransferaseenzyme
DB00993AzathioprineXanthine dehydrogenase/oxidaseenzyme
DB00993AzathioprineGlutathione S-transferase A1enzyme
DB00993AzathioprineGlutathione S-transferase A2enzyme
DB00993AzathioprineGlutathione S-transferase Mu 1enzyme
DB00993AzathioprineRas-related C3 botulinum toxin substrate 1target
DB00993AzathioprineCytochrome P450 1A2enzyme
DB00531CyclophosphamideDNAtarget
DB00531CyclophosphamideCytochrome P450 2B6enzyme
DB00531CyclophosphamideCytochrome P450 2C9enzyme
DB00531CyclophosphamideCytochrome P450 3A4enzyme
DB00531CyclophosphamideCytochrome P450 2C19enzyme
DB00531CyclophosphamideCytochrome P450 2A6enzyme
DB00531CyclophosphamideCytochrome P450 2C18enzyme
DB00531CyclophosphamideCytochrome P450 2C8enzyme
DB00531CyclophosphamideCytochrome P450 3A5enzyme
DB00531CyclophosphamideNuclear receptor subfamily 1 group I member 2target
DB00091CyclosporineCalcium signal-modulating cyclophilin ligandtarget
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase Atarget
DB00091CyclosporineCalcineurin subunit B type 2target
DB00091CyclosporineCytochrome P450 3A5enzyme
DB00091CyclosporineCytochrome P450 3A4enzyme
DB00091CyclosporineCytochrome P450 3A7enzyme
DB00091CyclosporineP-glycoprotein 1transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 2transporter
DB00091CyclosporineBile salt export pumptransporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1A2transporter
DB00091CyclosporineIleal sodium/bile acid cotransportertransporter
DB00091CyclosporineSodium/bile acid cotransportertransporter
DB00091CyclosporineSolute carrier family 22 member 6transporter
DB00091CyclosporineMultidrug resistance-associated protein 7transporter
DB00091CyclosporineCanalicular multispecific organic anion transporter 1transporter
DB00091CyclosporineATP-binding cassette sub-family G member 2transporter
DB00091CyclosporineSolute carrier organic anion transporter family member 1B1transporter
DB00091CyclosporineCytochrome P450 2C19enzyme
DB00091CyclosporineCytochrome P450 2C9enzyme
DB00091CyclosporineCytochrome P450 2D6enzyme
DB00091CyclosporinePeptidyl-prolyl cis-trans isomerase F, mitochondrialtarget
DB00091CyclosporineSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB01281Abatacept1Completed1
DB06399Atacicept1Terminated1
DB00531Cyclophosphamide1Completed1
DB01073Fludarabine1Completed1
DB09570Ixazomib1Terminated1
DB00864Tacrolimus1Completed1
DB01281Abatacept1 / 2Completed1
DB00531Cyclophosphamide1 / 2Completed1
DB12991Deoxyspergualin1 / 2Completed1
DB12692Gusperimus1 / 2Completed1
DB12943Milatuzumab1 / 2Recruiting1
DB01281Abatacept2Completed1
DB00316Acetaminophen2Completed1
DB11976Anifrolumab2Active Not Recruiting1
DB00993Azathioprine2Completed2
DB00993Azathioprine2Recruiting1
DB08879Belimumab2Completed1
DB00531Cyclophosphamide2Completed3
DB00531Cyclophosphamide2Recruiting1
DB00531Cyclophosphamide2Unknown Status1
DB00091Cyclosporine2Completed1
DB01075Diphenhydramine2Completed1
DB00005Etanercept2Terminated1
DB12233Iguratimod2Recruiting1
DB06685Laquinimod2Completed1
DB00959Methylprednisolone2Active Not Recruiting1
DB00959Methylprednisolone2Completed2
DB00688Mycophenolate mofetil2Active Not Recruiting1
DB00688Mycophenolate mofetil2Completed2
DB00688Mycophenolate mofetil2Not Yet Recruiting1
DB00688Mycophenolate mofetil2Terminated2
DB01024Mycophenolic acid2Active Not Recruiting1
DB01024Mycophenolic acid2Completed1
DB08935Obinutuzumab2Active Not Recruiting1
DB00860Prednisolone2Completed2
DB00635Prednisone2Active Not Recruiting1
DB00635Prednisone2Completed4
DB00073Rituximab2Completed1
DB06475Ruplizumab2Completed1
DB00864Tacrolimus2Unknown Status1
DB04942Tamibarotene2Unknown Status1
DB04906Voclosporin2Active Not Recruiting1
DB11693Voclosporin2Active Not Recruiting1
DB04906Voclosporin2Completed1
DB11693Voclosporin2Completed1
DB06399Atacicept2 / 3Terminated1
DB00531Cyclophosphamide2 / 3Unknown Status1
DB00065Infliximab2 / 3Terminated1
DB01097Leflunomide2 / 3Completed1
DB00688Mycophenolate mofetil2 / 3Terminated1
DB00635Prednisone2 / 3Completed1
DB14277Tripterygium wilfordii whole2 / 3Unknown Status1
DB01281Abatacept3Completed1
DB06662Abetimus3Completed1
DB06662Abetimus3Terminated1
DB00316Acetaminophen3Completed1
DB00993Azathioprine3Completed3
DB00993Azathioprine3Terminated1
DB08879Belimumab3Active Not Recruiting1
DB00531Cyclophosphamide3Completed5
DB00531Cyclophosphamide3Terminated3
DB00091Cyclosporine3Withdrawn1
DB01075Diphenhydramine3Completed1
DB01097Leflunomide3Terminated1
DB00959Methylprednisolone3Completed1
DB12617Mizoribine3Completed1
DB00688Mycophenolate mofetil3Completed7
DB00688Mycophenolate mofetil3Terminated2
DB01024Mycophenolic acid3Terminated1
DB01024Mycophenolic acid3Withdrawn1
DB11988Ocrelizumab3Completed1
DB00860Prednisolone3Completed1
DB00860Prednisolone3Terminated1
DB00860Prednisolone3Withdrawn1
DB00635Prednisone3Completed3
DB00635Prednisone3Terminated2
DB00073Rituximab3Completed1
DB00073Rituximab3Terminated1
DB00073Rituximab3Withdrawn1
DB00864Tacrolimus3Completed5
DB00864Tacrolimus3Terminated1
DB00864Tacrolimus3Withdrawn1
DB11693Voclosporin3Active Not Recruiting1
DB11693Voclosporin3Recruiting1
DB09274Artesunate4Recruiting1
DB00993Azathioprine4Completed1
DB00188Bortezomib4Withdrawn1
DB01285Corticotropin4Recruiting1
DB09547Corticotropin4Recruiting1
DB00531Cyclophosphamide4Completed1
DB00331Metformin4Not Yet Recruiting1
DB00959Methylprednisolone4Completed1
DB00688Mycophenolate mofetil4Completed2
DB00688Mycophenolate mofetil4Recruiting3
DB00806Pentoxifylline4Not Yet Recruiting1
DB00860Prednisolone4Completed2
DB00864Tacrolimus4Completed4
DB00864Tacrolimus4Recruiting1
DB00864Tacrolimus4Terminated1
DB11842Angiotensin IINot AvailableRecruiting1
DB00993AzathioprineNot AvailableCompleted1
DB00993AzathioprineNot AvailableRecruiting1
DB00531CyclophosphamideNot AvailableCompleted1
DB00531CyclophosphamideNot AvailableRecruiting1
DB00091CyclosporineNot AvailableRecruiting1
DB00584EnalaprilNot AvailableRecruiting1
DB01611HydroxychloroquineNot AvailableRecruiting1
DB12233IguratimodNot AvailableNot Yet Recruiting1
DB00678LosartanNot AvailableRecruiting1
DB12952MethylprednisoneNot AvailableRecruiting1
DB00688Mycophenolate mofetilNot AvailableCompleted4
DB00688Mycophenolate mofetilNot AvailableRecruiting2
DB01024Mycophenolic acidNot AvailableRecruiting1
DB00860PrednisoloneNot AvailableRecruiting1
DB00635PrednisoneNot AvailableRecruiting1
DB00073RituximabNot AvailableRecruiting1
DB00073RituximabNot AvailableWithdrawn1
DB00864TacrolimusNot AvailableActive Not Recruiting1
DB00864TacrolimusNot AvailableCompleted5
DB00864TacrolimusNot AvailableRecruiting1
DB14277Tripterygium wilfordii wholeNot AvailableCompleted2