Age-Related Macular Degeneration (ARMD)

Also known as: Age-related macular degeneration / Macular Degeneration / Senile macular degeneration / Macular degeneration senile / Macular degeneration (senile) of retina, unspecified

DrugDrug NameDrug Description
DB00460VerteporfinVerteporfin, marketed as Visudyne, is a benzoporphyrin derivative. It is used as a photosensitizer in photodynamic therapy to eliminate abnormal blood vessels in wet form macular degeneration. Verteporfin accumulates in these abnormal blood vessels and, when stimulated by nonthermal red light with a wavelength of 693 nm in the presence of oxygen, produces highly reactive short-lived singlet oxygen and other reactive oxygen radicals, resulting in local damage to the endothelium and blockage of the vessels.
DrugDrug NameTargetType
DrugDrug NamePhaseStatusCount
DB00878Chlorhexidine0Recruiting1
DB06812Povidone-iodine0Recruiting1
DB01270Ranibizumab0Completed1
DB11981Elamipretide1Active Not Recruiting1
DB12608Emixustat1Completed1
DB12812Palomid 5291Completed2
DB06325Pegpleranib1Completed1
DB01270Ranibizumab1Completed1
DB06647Volociximab1Completed1
DB08885Aflibercept1 / 2Completed1
DB00112Bevacizumab1 / 2Completed1
DB06322Carotuximab1 / 2Completed1
DB11981Elamipretide1 / 2Completed1
DB12577Fosbretabulin1 / 2Completed1
DB00166Lipoic acid1 / 2Completed1
DB11138Lutein1 / 2Unknown Status1
DB00688Mycophenolate mofetil1 / 2Recruiting1
DB01270Ranibizumab1 / 2Completed3
DB01270Ranibizumab1 / 2Recruiting1
DB05896Sirna-0271 / 2Completed1
DB00877Sirolimus1 / 2Completed2
DB00877Sirolimus1 / 2Terminated1
DB00864Tacrolimus1 / 2Recruiting1
DB00620Triamcinolone1 / 2Completed1
DB11176Zeaxanthin1 / 2Unknown Status1
DB05069ATG0032Completed1
DB00051Adalimumab2Completed1
DB08885Aflibercept2Completed1
DB08885Aflibercept2Recruiting1
DB08885Aflibercept2Terminated1
DB00112Bevacizumab2Terminated2
DB00190Carbidopa2Recruiting1
DB06322Carotuximab2Recruiting1
DB00111Daclizumab2Completed1
DB00869Dorzolamide2Completed1
DB01257Eculizumab2Completed1
DB11981Elamipretide2Recruiting1
DB01590Everolimus2Terminated1
DB00591Fluocinolone acetonide2Terminated1
DB00065Infliximab2Completed1
DB01235Levodopa2Recruiting1
DB00657Mecamylamine2Completed1
DB00331Metformin2Recruiting1
DB00688Mycophenolate mofetil2Withdrawn1
DB05650OT-5512Unknown Status1
DB01270Ranibizumab2Completed4
DB01270Ranibizumab2Enrolling by Invitation1
DB01270Ranibizumab2Recruiting1
DB01270Ranibizumab2Terminated4
DB01270Ranibizumab2Withdrawn1
DB00203Sildenafil2Terminated1
DB05896Sirna-0272Terminated1
DB00877Sirolimus2Completed2
DB00877Sirolimus2Terminated1
DB09153Sodium chloride2Completed1
DB06461Squalamine2Withdrawn1
DB00864Tacrolimus2Withdrawn1
DB11926Tesidolumab2Completed1
DB00373Timolol2Completed1
DB00620Triamcinolone2Completed1
DB00460Verteporfin2Completed1
DB04895Pegaptanib2 / 3Completed2
DB01270Ranibizumab2 / 3Completed1
DB01270Ranibizumab2 / 3Terminated1
DB00620Triamcinolone2 / 3Unknown Status1
DB08885Aflibercept3Not Yet Recruiting1
DB08885Aflibercept3Recruiting1
DB08885Aflibercept3Terminated1
DB00112Bevacizumab3Completed1
DB00112Bevacizumab3Recruiting2
DB00112Bevacizumab3Terminated1
DB00112Bevacizumab3Withdrawn1
DB14864Brolucizumab3Not Yet Recruiting2
DB14864Brolucizumab3Recruiting1
DB00159Icosapent3Completed1
DB11138Lutein3Completed1
DB04895Pegaptanib3Unknown Status1
DB06325Pegpleranib3Terminated3
DB01270Ranibizumab3Active Not Recruiting2
DB01270Ranibizumab3Completed5
DB01270Ranibizumab3Recruiting2
DB01270Ranibizumab3Terminated2
DB06461Squalamine3Active Not Recruiting1
DB00460Verteporfin3Completed1
DB11176Zeaxanthin3Completed1
DB08885Aflibercept4Completed3
DB00112Bevacizumab4Completed2
DB12460Conbercept4Completed1
DB12460Conbercept4Not Yet Recruiting1
DB01234Dexamethasone4Completed1
DB04895Pegaptanib4Recruiting1
DB04895Pegaptanib4Terminated1
DB01270Ranibizumab4Completed7
DB01270Ranibizumab4Not Yet Recruiting2
DB01270Ranibizumab4Terminated2
DB00460Verteporfin4Completed2
DB08885AfliberceptNot AvailableCompleted2
DB01086BenzocaineNot AvailableCompleted1
DB00112BevacizumabNot AvailableCompleted2
DB00668EpinephrineNot AvailableCompleted1
DB00465KetorolacNot AvailableCompleted1
DB00281LidocaineNot AvailableCompleted1
DB00218MoxifloxacinNot AvailableCompleted1
DB11133Omega-3 fatty acidsNot AvailableActive Not Recruiting1
DB04895PegaptanibNot AvailableCompleted1
DB00807ProparacaineNot AvailableCompleted1
DB01270RanibizumabNot AvailableCompleted6
DB01270RanibizumabNot AvailableRecruiting1
DB01270RanibizumabNot AvailableUnknown Status3