Acute Coronary Syndromes (ACS)

Also known as: ACS - Acute Coronary Syndrome / ACS (Acute Coronary Syndrome) / Coronary Acute Syndrome / Acute Coronary Syndrome (ACS) / Acute Coronary Syndromes / Acute Coronary Syndrome

DrugDrug NameDrug Description
DB00945Acetylsalicylic acidA salicylate used to treat pain, fever, inflammation, migraines, and reducing the risk of major adverse cardiovascular events.
DB00006BivalirudinA direct thrombin inhibitor used to treat heparin-induced thrombocytopenia and to prevent thrombosis during percutaneous coronary intervention.
DB00758ClopidogrelAn antiplatelet agent used to prevent blood clots in peripheral vascular disease, coronary artery disease, and cerebrovascular disease.
DB01225EnoxaparinA low molecular weight heparin used for the prophylaxis of deep vein thrombosis and ischemic complications of unstable angina and non-Q-wave myocardial infarction, when concurrently administered with aspirin.
DB00063EptifibatideA peptide-based antagonist for glycoprotein IIb/IIIa used in the medical management of myocardial infarction and as an adjunct to percutaneous coronary intervention.
DB08816TicagrelorA P2Y12 platelet inhibitor used in patients with a history of myocardial infarction or with acute coronary syndrome (ACS) to prevent future myocardial infarction, stroke and cardiovascular death.
DrugDrug NameTargetType
DB00945Acetylsalicylic acidProstaglandin G/H synthase 1target
DB00945Acetylsalicylic acidProstaglandin G/H synthase 2target
DB00945Acetylsalicylic acidAldo-keto reductase family 1 member C1target
DB00945Acetylsalicylic acidSolute carrier family 22 member 6transporter
DB00945Acetylsalicylic acidP-glycoprotein 1transporter
DB00945Acetylsalicylic acidCytochrome P450 2C19enzyme
DB00945Acetylsalicylic acidCytochrome P450 2C9enzyme
DB00945Acetylsalicylic acid5'-AMP-activated protein kinasetarget
DB00945Acetylsalicylic acidEndothelin-1 receptortarget
DB00945Acetylsalicylic acidCellular tumor antigen p53target
DB00945Acetylsalicylic acid78 kDa glucose-regulated proteintarget
DB00945Acetylsalicylic acidRibosomal protein S6 kinase alpha-3target
DB00945Acetylsalicylic acidNF-kappa-B inhibitor alphatarget
DB00945Acetylsalicylic acidTumor necrosis factor-inducible gene 6 proteintarget
DB00945Acetylsalicylic acidCaspase-1target
DB00945Acetylsalicylic acidCaspase-3target
DB00945Acetylsalicylic acidInhibitor of nuclear factor kappa-B kinase subunit betatarget
DB00945Acetylsalicylic acidExtracellular signal-regulated kinase (ERK)target
DB00945Acetylsalicylic acidG1/S-specific cyclin-D1target
DB00945Acetylsalicylic acidMyc proto-oncogene proteintarget
DB00945Acetylsalicylic acidProliferating cell nuclear antigentarget
DB00945Acetylsalicylic acidCyclin Atarget
DB00945Acetylsalicylic acidUDP-glucuronosyltransferase 1-6enzyme
DB00945Acetylsalicylic acidArylamine N-acetyltransferase 2enzyme
DB00945Acetylsalicylic acidSolute carrier family 22 member 8transporter
DB00006BivalirudinProthrombintarget
DB00006BivalirudinMyeloperoxidaseenzyme
DB00758ClopidogrelP2Y purinoceptor 12target
DB00758ClopidogrelCytochrome P450 3A4enzyme
DB00758ClopidogrelCytochrome P450 2B6enzyme
DB00758ClopidogrelCytochrome P450 3A5enzyme
DB00758ClopidogrelCytochrome P450 2C19enzyme
DB00758ClopidogrelCytochrome P450 2C9enzyme
DB00758ClopidogrelCytochrome P450 1A2enzyme
DB00758ClopidogrelCytochrome P450 2C8enzyme
DB00758ClopidogrelLiver carboxylesterase 1enzyme
DB00758ClopidogrelP-glycoprotein 1transporter
DB00758ClopidogrelSolute carrier family 22 member 1transporter
DB00758ClopidogrelSolute carrier family 22 member 2transporter
DB01225EnoxaparinAntithrombin-IIItarget
DB01225EnoxaparinCoagulation factor Xtarget
DB01225EnoxaparinMyeloperoxidaseenzyme
DB00063EptifibatideIntegrin beta-3target
DB08816TicagrelorCytochrome P450 3A4enzyme
DB08816TicagrelorP2Y purinoceptor 12target
DB08816TicagrelorP-glycoprotein 1transporter
DB08816TicagrelorCytochrome P450 2D6enzyme
DB08816TicagrelorCytochrome P450 2C9enzyme
DrugDrug NamePhaseStatusCount
DB05227APD7911Terminated2
DB00945Acetylsalicylic acid1Completed3
DB00945Acetylsalicylic acid1Terminated2
DB06605Apixaban1Completed1
DB01076Atorvastatin1Completed2
DB15047BMS-9193731Completed1
DB00758Clopidogrel1Completed2
DB00758Clopidogrel1Terminated3
DB01225Enoxaparin1Completed1
DB12270Losmapimod1Completed2
DB00218Moxifloxacin1Completed1
DB00213Pantoprazole1Completed1
DB06209Prasugrel1Terminated1
DB01098Rosuvastatin1Completed2
DB01104Sertraline1Terminated1
DB00641Simvastatin1Terminated1
DB08816Ticagrelor1Completed3
DB10803Typhoid Vi polysaccharide vaccine1Completed1
DB05692Vorapaxar1Completed1
DB12000Apabetalone1 / 2Completed1
DB01156Bupropion1 / 2Completed1
DB00215Citalopram1 / 2Completed1
DB00215Citalopram1 / 2Withdrawn1
DB01590Everolimus1 / 2Recruiting1
DB01104Sertraline1 / 2Completed1
DB09499Thiosulfuric acid1 / 2Completed1
DB0581099mTc-glucarate2Completed1
DB05631ALT-20742Completed1
DB00945Acetylsalicylic acid2Completed2
DB09302Alirocumab2Recruiting1
DB06605Apixaban2Completed1
DB06605Apixaban2Terminated1
DB12046Atopaxar2Completed2
DB01076Atorvastatin2Completed1
DB12758Atreleuton2Completed1
DB06441Cangrelor2Completed1
DB00758Clopidogrel2Completed7
DB00758Clopidogrel2Recruiting1
DB00907Cocaine2Unknown Status1
DB12289Darexaban2Completed1
DB00633Dexmedetomidine2Unknown Status1
DB00063Eptifibatide2Completed2
DB00063Eptifibatide2Recruiting1
DB09303Evolocumab2Recruiting2
DB04945Hemoglobin2Completed1
DB01109Heparin2Completed1
DB05683Iodofiltic acid I-1232Completed1
DB11984Letaxaban2Completed1
DB00722Lisinopril2Recruiting1
DB12270Losmapimod2Completed1
DB00264Metoprolol2Recruiting1
DB11839PZ-1282Completed1
DB00761Potassium chloride2Recruiting1
DB11090Potassium nitrate2Recruiting1
DB06209Prasugrel2Completed3
DB00243Ranolazine2Terminated1
DB06228Rivaroxaban2Completed2
DB08816Ticagrelor2Completed4
DB08816Ticagrelor2Recruiting1
DB00775Tirofiban2Completed1
DB12310Trehalose2Recruiting1
DB05737Varespladib methyl2Completed1
DB12164Varespladib methyl2Completed1
DB00758Clopidogrel2 / 3Completed2
DB01394Colchicine2 / 3Completed1
DB01065Melatonin2 / 3Completed1
DB06209Prasugrel2 / 3Completed1
DB08816Ticagrelor2 / 3Completed2
DB00945Acetylsalicylic acid3Completed3
DB00945Acetylsalicylic acid3Not Yet Recruiting1
DB00945Acetylsalicylic acid3Terminated2
DB09302Alirocumab3Completed1
DB06203Alogliptin3Completed1
DB06605Apixaban3Terminated1
DB01076Atorvastatin3Completed3
DB01076Atorvastatin3Not Yet Recruiting1
DB01076Atorvastatin3Terminated1
DB00006Bivalirudin3Completed2
DB01156Bupropion3Completed1
DB06441Cangrelor3Completed1
DB06441Cangrelor3Terminated2
DB00758Clopidogrel3Completed13
DB00758Clopidogrel3Not Yet Recruiting1
DB00758Clopidogrel3Recruiting3
DB00758Clopidogrel3Terminated3
DB12181Dalcetrapib3Active Not Recruiting1
DB06311Darapladib3Completed1
DB00063Eptifibatide3Completed2
DB09303Evolocumab3Completed1
DB00569Fondaparinux3Completed1
DB11728Fondaparinux3Completed1
DB01109Heparin3Completed5
DB00151L-Cysteine3Recruiting1
DB09265Lixisenatide3Completed1
DB12270Losmapimod3Completed1
DB00524Metolazone3Not Yet Recruiting1
DB00264Metoprolol3Not Yet Recruiting1
DB00338Omeprazole3Terminated1
DB06635Otamixaban3Completed1
DB09140Oxygen3Completed2
DB06209Prasugrel3Completed11
DB06209Prasugrel3Recruiting2
DB06228Rivaroxaban3Completed1
DB06228Rivaroxaban3Recruiting1
DB01098Rosuvastatin3Completed2
DB00641Simvastatin3Completed1
DB08816Ticagrelor3Active Not Recruiting1
DB04902Ticagrelor3Completed2
DB08816Ticagrelor3Completed5
DB08816Ticagrelor3Not Yet Recruiting1
DB08816Ticagrelor3Recruiting3
DB08816Ticagrelor3Terminated1
DB00775Tirofiban3Completed1
DB00775Tirofiban3Withdrawn1
DB00177Valsartan3Not Yet Recruiting1
DB01273Varenicline3Completed1
DB05737Varespladib methyl3Terminated1
DB00163Vitamin E3Recruiting1
DB00054Abciximab4Completed1
DB00284Acarbose4Active Not Recruiting1
DB00316Acetaminophen4Completed1
DB00945Acetylsalicylic acid4Completed11
DB00945Acetylsalicylic acid4Recruiting6
DB00945Acetylsalicylic acid4Terminated1
DB00945Acetylsalicylic acid4Unknown Status1
DB09302Alirocumab4Completed1
DB00437Allopurinol4Not Yet Recruiting1
DB11598Antithrombin III human4Unknown Status1
DB06605Apixaban4Completed1
DB01076Atorvastatin4Completed8
DB01076Atorvastatin4Unknown Status1
DB01393Bezafibrate4Completed1
DB00006Bivalirudin4Completed1
DB00006Bivalirudin4Not Yet Recruiting1
DB00006Bivalirudin4Recruiting1
DB01373Calcium4Unknown Status1
DB06441Cangrelor4Completed1
DB06441Cangrelor4Not Yet Recruiting2
DB06441Cangrelor4Recruiting1
DB01136Carvedilol4Recruiting1
DB01166Cilostazol4Completed3
DB00215Citalopram4Terminated1
DB00758Clopidogrel4Completed17
DB00758Clopidogrel4Enrolling by Invitation1
DB00758Clopidogrel4Not Yet Recruiting3
DB00758Clopidogrel4Recruiting6
DB00758Clopidogrel4Terminated3
DB00758Clopidogrel4Unknown Status5
DB00758Clopidogrel4Withdrawn1
DB01394Colchicine4Unknown Status1
DB14726Dabigatran4Completed1
DB14726Dabigatran4Terminated1
DB06695Dabigatran etexilate4Terminated1
DB00343Diltiazem4Completed1
DB00841Dobutamine4Recruiting1
DB01225Enoxaparin4Completed4
DB01225Enoxaparin4Recruiting1
DB00187Esmolol4Unknown Status1
DB00736Esomeprazole4Completed2
DB00402Eszopiclone4Completed1
DB09303Evolocumab4Not Yet Recruiting1
DB01276Exenatide4Completed1
DB00973Ezetimibe4Completed3
DB00927Famotidine4Completed2
DB01039Fenofibrate4Active Not Recruiting1
DB01039Fenofibrate4Completed1
DB00569Fondaparinux4Completed1
DB01109Heparin4Completed2
DB01611Hydroxychloroquine4Recruiting1
DB00030Insulin human4Suspended1
DB09083Ivabradine4Unknown Status1
DB06725Lornoxicam4Completed1
DB00331Metformin4Recruiting1
DB00264Metoprolol4Completed1
DB00264Metoprolol4Recruiting1
DB00235Milrinone4Recruiting1
DB00471Montelukast4Terminated1
DB00295Morphine4Completed2
DB00622Nicardipine4Unknown Status1
DB06690Nitrous oxide4Completed1
DB00338Omeprazole4Unknown Status1
DB09140Oxygen4Completed1
DB00213Pantoprazole4Unknown Status1
DB00946Phenprocoumon4Completed1
DB00946Phenprocoumon4Terminated1
DB01022Phylloquinone4Completed1
DB14500Potassium4Completed1
DB06209Prasugrel4Active Not Recruiting3
DB06209Prasugrel4Completed10
DB06209Prasugrel4Not Yet Recruiting1
DB06209Prasugrel4Recruiting3
DB06209Prasugrel4Terminated3
DB06209Prasugrel4Unknown Status3
DB00175Pravastatin4Completed2
DB00178Ramipril4Unknown Status1
DB06228Rivaroxaban4Completed1
DB06228Rivaroxaban4Not Yet Recruiting1
DB06228Rivaroxaban4Recruiting2
DB01098Rosuvastatin4Completed5
DB01098Rosuvastatin4Recruiting1
DB01098Rosuvastatin4Unknown Status2
DB00641Simvastatin4Active Not Recruiting1
DB00641Simvastatin4Completed1
DB01261Sitagliptin4Recruiting1
DB00086Streptokinase4Completed1
DB00966Telmisartan4Unknown Status1
DB00031Tenecteplase4Recruiting1
DB08816Ticagrelor4Active Not Recruiting2
DB08816Ticagrelor4Completed14
DB08816Ticagrelor4Enrolling by Invitation1
DB08816Ticagrelor4Not Yet Recruiting5
DB08816Ticagrelor4Recruiting10
DB08816Ticagrelor4Terminated1
DB08816Ticagrelor4Unknown Status6
DB08816Ticagrelor4Withdrawn2
DB00775Tirofiban4Completed1
DB00775Tirofiban4Recruiting1
DB01273Varenicline4Unknown Status1
DB11094Vitamin D4Unknown Status1
DB00425Zolpidem4Unknown Status1
DB00945Acetylsalicylic acidNot AvailableActive Not Recruiting1
DB00945Acetylsalicylic acidNot AvailableTerminated1
DB00945Acetylsalicylic acidNot AvailableWithdrawn1
DB00009AlteplaseNot AvailableWithdrawn1
DB01076AtorvastatinNot AvailableUnknown Status2
DB00612BisoprololNot AvailableActive Not Recruiting1
DB01156BupropionNot AvailableCompleted1
DB00796Candesartan cilexetilNot AvailableTerminated1
DB00758ClopidogrelNot AvailableActive Not Recruiting2
DB00758ClopidogrelNot AvailableCompleted6
DB00758ClopidogrelNot AvailableRecruiting1
DB00758ClopidogrelNot AvailableWithdrawn1
DB06779DalteparinNot AvailableCompleted1
DB01225EnoxaparinNot AvailableWithdrawn1
DB00973EzetimibeNot AvailableUnknown Status1
DB11728FondaparinuxNot AvailableCompleted1
DB01109HeparinNot AvailableActive Not Recruiting1
DB00883Isosorbide dinitrateNot AvailableRecruiting1
DB00598LabetalolNot AvailableRecruiting1
DB00264MetoprololNot AvailableRecruiting1
DB00622NicardipineNot AvailableRecruiting1
DB00184NicotineNot AvailableCompleted1
DB00184NicotineNot AvailableRecruiting1
DB06209PrasugrelNot AvailableActive Not Recruiting1
DB06209PrasugrelNot AvailableCompleted1
DB00178RamiprilNot AvailableActive Not Recruiting1
DB06228RivaroxabanNot AvailableActive Not Recruiting1
DB06228RivaroxabanNot AvailableRecruiting3
DB01098RosuvastatinNot AvailableCompleted1
DB01098RosuvastatinNot AvailableRecruiting1
DB01098RosuvastatinNot AvailableUnknown Status1
DB01104SertralineNot AvailableCompleted1
DB00641SimvastatinNot AvailableUnknown Status1
DB01323St. John's WortNot AvailableWithdrawn1
DB00086StreptokinaseNot AvailableWithdrawn1
DB00966TelmisartanNot AvailableTerminated1
DB08816TicagrelorNot AvailableActive Not Recruiting2
DB08816TicagrelorNot AvailableCompleted9
DB08816TicagrelorNot AvailableRecruiting2
DB00775TirofibanNot AvailableTerminated1
DB01273VareniclineNot AvailableRecruiting1
DB00682WarfarinNot AvailableRecruiting1