Kaposi s Sarcoma (KS)

Also known as: Kaposi's sarcomas / Kaposi's sarcoma / Kaposi Sarcoma (KS) / Sarcoma, Kaposi / Kaposi´s Sarcoma / Kaposi Sarcoma / Kaposi' s Sarcoma / Multiple idiopathic hemorrhagic sarcoma / Multiple idiopathic haemorrhagic sarcoma / Kaposi's sarcoma, unspecified / Kaposi's sarcoma NOS / Multiple haemorrhagic sarcoma / Multiple hemorrhagic sarcoma

DrugDrug NameDrug Description
DB00105Interferon alfa-2bInterferon alpha 2b (human leukocyte clone hif-sn 206 protein moiety reduced). A type I interferon consisting of 165 amino acid residues with arginine in position 23. This protein is produced by recombinant DNA technology and resembles interferon secreted by leukocytes. It is used extensively as an antiviral or antineoplastic agent.
DB01229PaclitaxelPaclitaxel is a chemotherapeutic agent marketed under the brand name Taxol among others. Used as a treatment for various cancers, paclitaxel is a mitotic inhibitor that was first isolated in 1971 from the bark of the Pacific yew tree which contains endophytic fungi that synthesize paclitaxel. It is available as an intravenous solution for injection and the newer formulation contains albumin-bound paclitaxel marketed under the brand name Abraxane.
DB00570VinblastineAntitumor alkaloid isolated from Vinca rosea. (Merck, 11th ed.)
DB00541VincristineVincristine is an antitumor vinca alkaloid isolated from Vinca Rosea. It is marketed under several brand names, many of which have different formulations such as Marqibo (liposomal injection) and Vincasar. Vincristine is indicated for the treatment of acute leukaemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis. vincristine sulfate is often chosen as part of polychemotherapy because of lack of significant bone–marrow suppression (at recommended doses) and of unique clinical toxicity (neuropathy).
DrugDrug NameTargetType
DB00105Interferon alfa-2bInterferon alpha/beta receptor 2target
DB00105Interferon alfa-2bInterferon alpha/beta receptor 1target
DB00105Interferon alfa-2bCytochrome P450 1A2enzyme
DB01229PaclitaxelApoptosis regulator Bcl-2target
DB01229PaclitaxelTubulin beta-1 chaintarget
DB01229PaclitaxelCytochrome P450 2C8enzyme
DB01229PaclitaxelCytochrome P450 3A4enzyme
DB01229PaclitaxelCytochrome P450 3A5enzyme
DB01229PaclitaxelCytochrome P450 3A7enzyme
DB01229PaclitaxelBile salt export pumptransporter
DB01229PaclitaxelMultidrug resistance protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 1transporter
DB01229PaclitaxelMultidrug resistance-associated protein 7transporter
DB01229PaclitaxelCytochrome P450 19A1enzyme
DB01229PaclitaxelCytochrome P450 1B1enzyme
DB01229PaclitaxelSolute carrier organic anion transporter family member 1B3transporter
DB01229PaclitaxelNuclear receptor subfamily 1 group I member 2target
DB01229PaclitaxelMicrotubule-associated protein 4target
DB01229PaclitaxelMicrotubule-associated protein 2target
DB01229PaclitaxelMicrotubule-associated protein tautarget
DB01229PaclitaxelATP-binding cassette sub-family G member 2transporter
DB01229PaclitaxelCanalicular multispecific organic anion transporter 1transporter
DB00570VinblastineTubulin beta chaintarget
DB00570VinblastineTranscription factor AP-1target
DB00570VinblastineCytochrome P450 3A4enzyme
DB00570VinblastineMultidrug resistance protein 1transporter
DB00570VinblastineMultidrug resistance-associated protein 1transporter
DB00570VinblastineCanalicular multispecific organic anion transporter 1transporter
DB00570VinblastineMultidrug resistance-associated protein 6transporter
DB00570VinblastineBile salt export pumptransporter
DB00570VinblastineTubulin alpha-1A chaintarget
DB00570VinblastineTubulin delta chaintarget
DB00570VinblastineTubulin epsilon chaintarget
DB00570VinblastineTubulin gamma-1 chaintarget
DB00570VinblastineCytochrome P450 2D6enzyme
DB00570VinblastineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineTubulin beta chaintarget
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineMultidrug resistance protein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB00220Nelfinavir0Terminated1
DB09035Nivolumab0Recruiting1
DB12182Binetrakin1Completed1
DB00290Bleomycin1Completed3
DB00531Cyclophosphamide1Not Yet Recruiting1
DB00900Didanosine1Completed1
DB00997Doxorubicin1Completed3
DB00997Doxorubicin1Not Yet Recruiting1
DB00773Etoposide1Completed1
DB00773Etoposide1Not Yet Recruiting1
DB14740Hyaluronidase1Not Yet Recruiting1
DB00034Interferon Alfa-2a, Recombinant1Completed2
DB00105Interferon alfa-2b1Completed1
DB00011Interferon alfa-n11Completed2
DB00068Interferon beta-1b1Completed1
DB06186Ipilimumab1Recruiting1
DB00563Methotrexate1Not Yet Recruiting1
DB09035Nivolumab1Recruiting1
DB09037Pembrolizumab1Recruiting1
DB08910Pomalidomide1Recruiting1
DB00635Prednisone1Not Yet Recruiting1
DB00073Rituximab1Not Yet Recruiting1
DB00020Sargramostim1Completed2
DB05686Sivifene1Completed1
DB00398Sorafenib1Terminated1
DB12828TNP-4701Completed1
DB09266Technetium Tc-99m tilmanocept1Recruiting1
DB00541Vincristine1Completed3
DB00541Vincristine1Not Yet Recruiting1
DB00943Zalcitabine1Completed1
DB00495Zidovudine1Completed6
DB12764ABC-2946401 / 2Withdrawn1
DB08910Pomalidomide1 / 2Active Not Recruiting1
DB05471SGN-301 / 2Completed1
DB06013Aldoxorubicin2Completed1
DB00523Alitretinoin2Completed1
DB00112Bevacizumab2Completed3
DB00307Bexarotene2Completed1
DB00290Bleomycin2Completed1
DB00900Didanosine2Completed1
DB00390Digoxin2Recruiting1
DB00997Doxorubicin2Completed3
DB00773Etoposide2Completed1
DB01590Everolimus2Terminated1
DB00099Filgrastim2Completed1
DB00034Interferon Alfa-2a, Recombinant2Completed1
DB00105Interferon alfa-2b2Completed1
DB01204Mitoxantrone2Completed1
DB00220Nelfinavir2Completed1
DB01229Paclitaxel2Completed1
DB09037Pembrolizumab2Recruiting1
DB00503Ritonavir2Completed1
DB06659Rostaporfin2Completed1
DB14797SEphB4-HSA2Not Yet Recruiting1
DB06436Semaxanib2Completed1
DB09266Technetium Tc-99m tilmanocept2Completed1
DB01610Valganciclovir2Active Not Recruiting1
DB12082Vesnarinone2Completed1
DB00541Vincristine2Completed1
DB00495Zidovudine2Completed1
DB00290Bleomycin3Completed2
DB00290Bleomycin3Unknown Status1
DB00694Daunorubicin3Completed1
DB00997Doxorubicin3Completed4
DB00997Doxorubicin3Unknown Status1
DB00625Efavirenz3Active Not Recruiting1
DB00879Emtricitabine3Active Not Recruiting1
DB00773Etoposide3Active Not Recruiting1
DB05779Oglufanide3Completed1
DB00300Tenofovir disoproxil3Active Not Recruiting1
DB00541Vincristine3Completed2
DB00541Vincristine3Unknown Status1
DB00523AlitretinoinNot AvailableCompleted1
DB04835MaravirocNot AvailableCompleted1
DB06436SemaxanibNot AvailableCompleted1